Embedded Files
Keywords : Medical robotics, Robotized needle insertion, Small animal, in vivo evaluation
Publications
Illustrations & Videos
Cameras / Robot registration
Mouse bed registrated by structured light
Accurate needle positioning on carbon tip
Positioning device (IEEE TBME 2013)
Project leads by Jean-Marc Egly from IGBMC, in collaboration with robotic ICubeTeam and IRCAD. A robotic positioning device was developed. CT-Scanner image was registrated with the robot, the camera set and the real target. The system was tested in phantom and in vivo, on mouses. The study shows that robotic assistance could be routinely used in biomedical research laboratories to improve existing procedures, allowing automated accurate treatments and limited animal sacrifices.
In-Vivo Robotized Needle Insertion from CT-scan planification
Keywords : Robotics, Small animal, Needle Insertion, Structured light
Medical results (Plos One 2014)
Mice bearing orthotopic HCC tumors were treated by recurrent automated robotized intratumoral injection (IT, n = 3) or manual intraperitoneal (IP, n = 3) of Doxorubicin; untreated mice (n = 3) were used as control of tumor growth. (A) Representative 3-weeks follow-up by µCT scan imaging and 3D reconstruction of tumor development. Volumes of the tumors resected at the end of the experiment were measured. (B) Tumor volume was computed at each time point from the 3D reconstructions of the tumors in untreated (left), IT (middle) or IP (right) injected mice (mean +/− SEM, star (*) indicates a difference with untreated control at the same time point with p<0.05).
Treatment of Hep55.1C mouse HCC model by Doxorubicin
Page updated
Google Sites
Report abuse