Centre for Microbial and Fermentation Technology (CMFT)
Department of Microbiology, Osmania University, Hyderabad, Telangana
-500007
Department of Microbiology, Osmania University, Hyderabad, Telangana
-500007
Mohammad Saddam Hussain, Priyadarshini Boda, Anjana Devi Tangutur, Bhima Bhukya. (2026). Sustainable valorization of grape juice waste into a biocompatible synbiotic functional medium using Betaine-Glycerol NADES. Process Biochemistry, 170, 54–66.
Anthappagudem A., Mohammad Saddam Hussain, Priyadarshini Boda, et al. (2026). Characterizing probiotic properties of the Saccharomyces cerevisiae ABO1 strain isolated from toddy palm nectar. Brazilian Journal of Microbiology, 57, 249.
Priyadarshini Boda, Mohammad Saddam Hussain, Bhima Bhukya. (2026). Bactericidal and Cell Membrane Disruption Potential of Protein Extract from Buttermilk-Derived Probiotic Pediococcus pentosaceus OBK05 against Salmonella typhimurium ATCC 14028. Frontiers in Microbiology
Batchu, U.R., Anumalla, M., Mandhayan, P.M., Nageswara, S., Bhukya, B., Rao, K.R.S.S., Shetty, P.R. (2025). Isolation, purification and characterization of novel uricase from Delftia tsuruhatensis IICT-RSP4. Antonie van Leeuwenhoek, 118, 163
Vanitha, S., Bhukya, B., Anuradha, K. (2025). Influence of Prebiotic Fructooligosaccharides on the Growth of Probiotic Lactobacillus spp. to Produce Postbiotic Short Chain Fatty Acids Evaluated using Gas Chromatography. Journal of Pure and Applied Microbiology, 19, 2395–2409.
Venkateswarlu Kojja, Dinesh Kumar, Praveen Kumar Kalavagunta, Bhima Bhukya, Anjana Devi Tangutur, Prasanta Kumar Nayak. (2025). 2-(Diarylalkyl)aminobenzothiazole derivatives induce autophagy and apoptotic death through SIRT inhibition and P53 activation in MCF7 breast cancer cells. Computational Biology and Chemistry, 116, 108395.
Anumalla, M., Batchu, U.R., Singh, N.K., et al. (2025). Draft Genome Analysis of Delftia tsuruhatensis IICT-RSP4, a Strain with Uricase Potential Isolated from Soil. Indian Journal of Microbiology.
Ravula Shrikantha, Sirasani Satyanarayana, Rathod Aravind Kumar, Mohammad Saddam Hussain, Bhima Bhukya, Ravada Kishore, Jajula Kashanna. (2025). Ceric(IV) Ammonium Nitrate Mediated Cross Dehydrogenative Coupling of Ortho-Benzoylbenzofurans with Phosphites and Their Anti-Microbial Evaluation. International Journal of Environmental Sciences
D. Srilatha, S. Chaitanya Kumari, Bhima Bhukya, K. Anuradha. (2024). Screening and isolation of Bacillus isolates for Levansucrase activity and for Levan Production. South Asian Journal of Experimental Biology, 14(6),
Anuradha Barigela, Bhima Bhukya. (2024). Optimized Biomass Production of Probiotic Bacterium Pediococcus acidilactici TMAB26 Using Pineapple Peel: A Response Surface Methodology Approach. Current Research in Nutrition and Food Science, 12(3), 1316–1325.
Ganapathiwar, S., Pappula, R., Banothu, A.K., et al. (2023). Causatum of Probiotic Yeast Saccharomyces cerevisiae SBO1 Supplementation on Growth and Aflatoxin Amelioration in Broilers. Indian Journal of Microbiology.
Lunavath, R., Mohammad, S.H., Bhukya, K.K., Bhukya, B., et al. (2023). Antimycotic effect of 3-phenyllactic acid produced by probiotic bacterial isolates against Covid-19 associated mucormycosis causing fungi. PLOS ONE, 18(3), e0279118.
Bhukya, K. K., & Bhukya, B. (2023). Exploration of Antidiabetic, Cholesterol-Lowering, and Anticancer Upshot of Probiotic Bacterium Pediococcus pentosaceus OBK05 Strain of Buttermilk. Probiotics and Antimicrobial Proteins, 15(6), 1484–1500.
Swaruparani Ganapathiwar, Bhima Bhukya. (2023). In vitro assessment for the probiotic potential of Pichia kudriavzevii. Bioinformation
Lunavath, Madhavi, Swamy, Mahadeva, Bhukya, Bhima. (2023). Isolation of plant probiotics (Bacillus subtilis) and its effect on germination of tomato seeds at drought stress. Biochemical & Cellular Archives, 23(1), 149–156.
Anthappagudem, A., Enaganti, S., & Bhukya, B. Mutational and molecular docking studies of CYP3A4. Journal of Applied Biology & Biotechnology.
Mohammad, S.H., Bhukya, B. (2022). Biotransformation of toxic lignin and aromatic compounds of lignocellulosic feedstock into eco-friendly biopolymers by Pseudomonas putida KT2440. Bioresource Technology, 363, 128001.
Kumar, R.N., Surekha, M.V., Ramalingam, B., Kumar, P.U., Polasa, K., Hemalatha, R., Bhima, B., et al. (2022). Oral Toxicity Study for Salmonella Killing Lytic Bacteriophage NINP13076 in BALB/c Mice and Its Effect on Probiotic Microbiota. Current Microbiology, 79(3), 89.
Ashok, D., Thara, G., Dharavath, R., et al. (2022). Microwave Assisted Synthesis of Flavonoid Based 1,2,3-Triazole and Isoxazole Derivatives, Their Antibacterial, Antioxidant, and Anticancer Activities. Russian Journal of General Chemistry, 92, 718–724.
Sunkar, B., Bhukya, B. (2022). An Approach to Correlate Chemical Pretreatment to Digestibility Through Biomass Characterization by SEM, FTIR and XRD. Frontiers in Energy Research, 10, 802522.
Bhukya, K.K., Bhukya, B. (2021). Unraveling the probiotic efficiency of bacterium Pediococcus pentosaceus OBK05 isolated from buttermilk: An in vitro study for cholesterol assimilation potential and antibiotic resistance status. PLOS ONE, 16(11), e0259702.
Nagamani Pammi, Kiran Kumar Bhukya, Ravi Kumar Lunavath, Bhima Bhukya. (2021). Bioprospecting of Palmyra Palm (Borassus flabellifer) Nectar: Unveiling the Probiotic and Therapeutic Potential of the Traditional Rural Drink. Frontiers in Microbiology, 12, 683996.
Sunkar, B., Bhukya, B. (2021). Bi-phasic hydrolysis of corncobs for the extraction of total sugars and ethanol production using inhibitor resistant and thermotolerant yeast, Pichia kudriavzevii. Biomass and Bioenergy, 153, 106230.
Praveen Kumar Keshav, Chandrashekhar Banoth, Srinivas Naik Kethavath, Bhima Bhukya. (2023). Lignocellulosic ethanol production from cotton stalk: an overview on pretreatment, saccharification and fermentation methods for improved bioconversion process. Biomass Conversion and Biorefinery
Barigela, A., & Bhukya, B. (2021). Probiotic Pediococcus acidilactici strain from tomato pickle displays anti-cancer activity and alleviates gut inflammation in-vitro. 3 Biotech, 11(1), 23.
Saiqali, M.A., Tangutur, A.D., Bhukya, B. (2021). Peptides and low molecular weight polypeptides of Azadirachta indica seeds as new weapons against cancer cells and superbugs. Phytomedicine Plus, 1(4), 100118.
Srinivas Banoth, Anjana Devi Tangutur, Archana Anthappagudem, Janaki Ramaiah, Bhima Bhukya. (2020). Cloning and in vivo metabolizing activity study of CYP3A4 on amiodarone drug residues: A possible probiotic and therapeutic option. Biomedicine & Pharmacotherapy, 127, 110128.
Bindu Sunkar, Balakrishna Kannoju, Bhima Bhukya. (2020). Optimized Production of Xylanase by Penicillium purpurogenum and Ultrasound Impact on Enzyme Kinetics for the Production of Monomeric Sugars from Pretreated Corn Cobs. Frontiers in Microbiology, 11, 772.
Kumar Ramachandrappa Naveen, Bhima Bhukya, Kumar Putchaa Uday, Ghosh Sudip. (2020). Bio-control of Salmonella spp. in carrot salad and raw chicken skin using lytic bacteriophages. LWT - Food Science and Technology, 122, 109039.
Chandrasekhar Banoth, Srinivas Naik Kethavath, Praveen Kumar Keshav, Bhima Bhukya. (2020). Selection of stress tolerant Saccharomyces cerevisiae strains isolated from sloughing off soil for bioethanol production using Prosopis juliflora. Research Journal of Biotechnology, 15(1),
Praveen Kumar Keshav, Chandrasekhar Banoth, Archana Anthappagudem, Venkateswar Rao Linga, Bhima Bhukya. (2018). Sequential acid and enzymatic saccharification of steam exploded cotton stalk and subsequent ethanol production using Scheffersomyces stipitis NCIM. Industrial Crops and Products, 125, 462–467.
Mohammed Al Saiqali, Anjana Devi Tangutur, Chandrasekhar Banoth, Bhima Bhukya. (2018). Antimicrobial and anticancer potential of low molecular weight polypeptides extracted and characterized from leaves of Azadirachta indica. International Journal of Biological Macromolecules, 114, 906–921.
Chandrasekhar Banoth, Bindu Sunkar, Pruthvi Raj Tondamanati, Bhima Bhukya. (2017). Improved physicochemical pretreatment and enzymatic hydrolysis of rice straw for bioethanol production by yeast fermentation. 3 Biotech, 7, 334.
Banoth Srinivas, Ganapathiwar Swarupa Rani, Bhukya Kiran Kumar, Banoth Chandrasekhar, Kommalapati Vamsi Krishna, Tangutur Anjana Devi, Bhukya Bhima. (2016). Evaluating the probiotic and therapeutic potentials of Saccharomyces cerevisiae strain (OBS2) isolated from fermented nectar of toddy palm. AMB Express, 7(2), 1–14.
Kannoju Balakrishna, Ganapathiwar Swaruparani, Nunavath Hanumalal, Sunkar Bindu, Bhukya Bhima. (2017). Plausible exploitation of Jatropha de-oiled seed cake for lipase and phytase production and simultaneous detoxification by Candida parapsilosis isolated from poultry garbage. Bioresource Technology, 225, 215–224.
Dipti W. Pitta, Zhengxia Dou, Sanjay Kumar, Nagaraju Indugu, John Daniel Toth, Bonnie Vecchiarelli, Bhima Bhukya. (2016). Metagenomic evidence of the prevalence and distribution patterns of antimicrobial resistance genes in dairy agroecosystems. Foodborne Pathogens and Disease, 13(6)
Hanumalal Nunavath, Chandrasekhar Banoth, Venkateswar Rao Talluri, Bhima Bhukya. (2020). An analysis of horseradish peroxidase enzyme for effluent treatment. Bioinformation, 12(6), 318–323.
Dipti W. Pitta, Nagaraju Indugu, Sanjay Kumar, Bonnie Vecchiarelli, Rohini Sinha, Linda D. Baker, Bhima Bhukya, James D. Ferguson. (2016). Metagenomic assessment of the functional potential of the rumen microbiome in Holstein dairy cows. Anaerobe, 38, 50–60
Vasu Namani, B. Goud, Y. Bharathi Kumari, Ramesh Kumbham, Kannoju Balakrishna, Bhukya Bhima. (2015). Design, Synthesis and Biological Evaluation of Benzimidazolyl and Benzothiazolyl Picolinamide Derivatives as Antimicrobial Agents. Asian Journal of Chemistry, 27(12), 4575–4578.
B. Bhima, Y. Ramana Reddy, M. Pawani, Sudhakara Reddy, L. Venkateswar Rao, D.W. Pitta. (2015). Influence of Stress-Resistant Yeast Culture (OBV9) Supplementation on the Productive Performance of Water Buffalo. Asian Journal of Animal and Veterinary Advances, 10(6), 260–270.
Chandrasekhar B and Bhima B. 2015. Cellulose as Sole Substrate for Bio Ethanol Production: Development of Structural Molecular Model of Endoglucanase III from Trichoderma Reesei Using Bioinformatic Tools. Int J Pharm Sci Res. 6(3): 1132-36.
B. Bhima, Y. Ramana Reddy, M. Sudhakara Reddy, M. Pawani, L. Venkateswar Rao. (2014). Effect of thermo-tolerant yeast on intake and nutrient digestibility in Murrah buffalo steers (Bubalus bubalis) fed straw based complete diet. Veterinary World, 7(7), 501–504.
Jaheer, Md., Ranjith Reddy, P., Bhima, B., Narsimha, N., Sujitha, P., Srinivas, B., Ch. Sarala Devi. (2014). Synthesis, spectro-analytical, computational and biological studies of novel 6-methyl-3-(1-(4-oxo-2-phenylquinazolin-3(4H)-ylimino)ethyl)-2H-pyran-2,4(3H)-dione and its Co(II), Cu(II) and Hg(II) metal complexes. IOSR Journal of Applied Chemistry, 7(6), 1–12.
M. Sudhakara Reddy, Y. Ramana Reddy, B. Bhima, Y. Thirupathaiah, A. Rajasekhar Reddy, L. Venkateswar Rao. (2013). Effect of different levels of thermotolerant probiotic yeast supplementation on biochemical and immune parameters in broilers. World Journal of Pharmacy and Pharmaceutical Sciences, 2(6), 4911–4916.
Dinesh Addla, Bhima, Balasubramanian Sridhar, Anjana Devi, Srinivas Kantevari. (2015). Design, synthesis and antimicrobial evaluation of novel 1-benzyl 2-butyl-4-chloroimidazole embodied 4-azafluorenones via molecular hybridization approach. Bioorganic & Medicinal Chemistry Letters, 22, 7475–7480.
B. Kiran Kumar, B. Bhima. (2012). Detoxification of anti-nutrients (tannins) present in fruit extracts for probiotic yeast production. International Journal of Applied Biology and Pharmaceutical Technology, 3(3), 275–279.
B. Bhima, T. Anjana Devi, M. Sudhakara Reddy, Y. Ramana Reddy, L. Venkateswar Rao. (2011). Optimized protein extraction from Saccharomyces cerevisiae for 2-D gel electrophoresis. Journal of Theoretical and Experimental Biology, 8(1&2), 77–84.
Bhukya Bhima, Marrivada Sudhakara Reddy, Tanguturu Anjana Devi, Yerradoddi Ramana Reddy, Linga Venkateswar Rao. (2010). Screening and characterization of stress tolerant Saccharomyces cerevisiae isolated from brewery effluents for animal probiotic applications. IIOAB Journal, 1(4), 32–39.
B. Bhima, Y. Ramana Reddy, M. Pavani, M. Sudhakara Reddy, L. Venkateswar Rao. (2010). In vitro evaluation of straw based complete diets supplemented with probiotic yeast. Indian Veterinary Journal, 87, 779–781.
B. Bhima, T. Anjana Devi, M. Sudhakara Reddy, Y. Ramana Reddy, L. Venkateswar Rao. (2010). Insights into the protein profiles of stress tolerant and mesophilic yeast by proteomics approach: a comparative study. International Journal of Applied Biology and Pharmaceutical Technology, 1(2), 349–359.
B. Bhima, Y. Ramana Reddy, M. Pavani, M. Sudhakara Reddy, L. Venkateswar Rao. (2009). Rumen fermentation pattern in Murrah buffalo steers fed on straw based complete diet supplemented with thermotolerant probiotic yeast (Saccharomyces cerevisiae) at graded levels. Indian Journal of Animal Nutrition, 26(3), 239–242.
G.V.N. Reddy, B. Bhima. (2003). Effect of yeast culture based diet on growth and nutrient utilization in deoni bull calves. Indian Journal of Animal Nutrition, 20(1), 101–104.
Bhima Bhukya and Boda Priyadarshini. (2026). Probiotics as Antifungals. In: Navigating the Challenge of Opportunistic Fungal Infections – Probiotics in Action. Springer Nature
Bhima Bhukya and Praveen K. Keshav. (2022) An Evaluation of Steam Explosion Pretreatment to Enhance the Digestibility of Lignocellulosic Biomass. John Wiley & Sons Ltd., Online ISBN:9781119735984, pp. 83-98.
Bhima Bhukya, Banoth Chandrasekhar, Keshav Praveen K, Hussain Mohammad Saddam and Ajmera Shantipriya. (2022). Biotechnological Production of Various Fungal Metabolites and Their Applications in White Biotechnology. ISBN: 978-981-5040-35-7, pp. 255–286. Bentham Science
Bhima Bhukya, Sunkar Bindu, Kannoju Balakrishna. (2021). Optimized Production of Xylanase by Penicillium purpurogenum and Ultrasound Impact on Enzyme Kinetics for the Production of Monomeric Sugars from Pretreated Corn Cobs. In Prime Archives in Microbiology (2nd ed.). Hyderabad, India: Vide Leaf. Pp. 1-32.
Bhima Bhukya, Banoth Srinivas and Anthappagudem Archana. (2019). Saccharomyces cerevisiae as Potential Probiotic: Strategies for Isolation and Selection. In: Applied Microbiology and Bioengineering, edited by Pratyoosh Shukla. ISBN 9780128154076, Pages 71-85, Elsevier Inc.
Anju, S., Aparna, Y., Bhukya, B. and Sarada, J. (2018). Novel Insights on the Bacillus Quorum Sensing Mechanism: Its Role in Competence, Virulence, Sporulation and Biofilm Formation. In: Implication of Quorum Sensing System in Biofilm Formation and Virulence, edited by Pallaval Veera Bramhachari. Springer Nature. Online ISBN 978-981-13-2429-1, pp 313–327
Bhima, B. and Saiqali, M.A. (2017). Antimicrobial Peptides from Plants and Their Applications. In: Microbial Biotechnology: Technological Challenges and Developmental Trends. Apple Academic Press. Pp.23
Bhima, B., Hanumalal, N. and Chandrasekhar, B. (2017). Yeast Saccharomyces cerevisiae: Efficient Biological Agent for Decolorization of Reactive Dyes Used in Textile Industry. In: Microbial Biotechnology: Technological Challenges and Developmental Trends. Apple Academic Press.
Venkateswar Rao, L., Bhima, B., Ramana Reddy, Y., Pavani, M. and Sudhakara Reddy, M. (2010). Effect of Different Levels of Thermotolerant Probiotic Yeast (Saccharomyces cerevisiae) on Intake, Nutrient Digestibility and Rumen Fermentation Pattern in Straw-Based Complete Diets Fed to Murrah Buffalo Steers. In: Current Topics on Bioprocesses in Food Industry. V. Asiatech Publishers, Inc., pp. 58–70.
Bhukya, Bhima (Editor). Introductory Microbiology, B.Sc. I Year, Semester I. Divya Lakshmi Publishers & Distributors.
Bhukya, Bhima (Editor). Laboratory Experiments in Microbiology. Professional Books Publisher.
Bhukya, Bhima (Editor). (2017). Microbial Biotechnology: Technological Challenges and Developmental Trends. CRC Press/Apple Academic Press.
Bhukya, Bhima (Co-Editor). (2021). Sustainable Utilization of Fungi in Agriculture and Industry. Mycology: Current and Future Development, Volume IV. Bentham Science Publishers.
Probiotic compositions expressing mutant cytochrome p450 with enhanced xenobiotic metabolizing activity and methods thereof.
Patent. No.201741031371 A. Date: 15/09/2017