Translational Research Laboratory

Principal Researcher, Dr. Hyung-Seop Han (한형섭)

(e-mail : hyuhan@kist.re.kr, google scholar)

“Translational Research Laboratory” focuses on the process of taking research results from the laboratory into the clinic so that it can directly benefit patients. Translational research incorporates aspects of both basic science and clinical research and requires skills and resources that are not readily available in a basic laboratory or an exclusively clinical setting. Our general research interests include state-of-the-art in-vitro, ex-vivo and in-vivo techniques for in-depth evaluation of the biomaterials.

중개임상연구실은 환자에게 직접적으로 도움이 될 수 있도록 연구소에서 개발된 기술을 병원으로 가져 오는 실용화 과정에 중점을 둡니다. 중개임상연구는 기초 과학 및 임상 연구의 측면을 모두 통합하기 때문에 기초연구 실험실이나 임상 환경에서는 쉽게 사용할 수 없는 기술과 리소스를 필요로 합니다. 우리 연구실의 일반적인 연구 관심사는 생체 재료의 심층 평가와 인증을 위한 최첨단 in-vitro, ex-vivo 및 in-vivo 실험 기법 등이 있습니다.

Academic Career

2003.9 ~ 2007.5 BSc degree, Biomedical Engineering, University of Iowa, U.S

2008.1 ~ 2009.5 MS degree, Biomedical Engineering, University of Iowa, U.S

2009.7 ~ 2011.7 Student Trainee, Center for Biomaterials, KIST

2012.9 ~ 2016.9 Research Scientist, Center for Biomaterials, KIST

2014.9 ~ 2015.9 Histotechnology Certification, Indiana University, School of Medicine, U.S

2016.10 ~ 2019.1 PhD degree, Medical Science, University of Oxford, U.K

2019.3 ~ 2023.2 Senior Research Scientist, Center for Biomaterials, KIST

2023.3 ~ Current Principal Research Scientist, Center for Biomaterials, KIST

Representative Research Works

1. Technology Transfer - Medical Hologram Display ~ $ 1 Million U.S Dollars (2022).

2. Technology Transfer - Condensation Energy Harvesting Electrical Stimulation System for Cell Therapy ~ 0.6 Million U.S Dollars (2023).

3. Synergistic stimulation of surface topography and biphasic electric current promotes muscle regeneration, Bioactive Materials (2022), 11, 118-129.

4. Computational design of Mg alloys with minimal galvanic corrosion, Journal of Magnesim and Alloys (2022) In Press.

5. Durable and Fatigue‐Resistant Soft Peripheral Neuroprosthetics for In Vivo Bidirectional Signaling, Journal of Magnesim and Alloys (2021) 9, 1373-1381.

6. Regulation of cell locomotion by nanosecond-laser-induced hydroxyapatite patterning, Bioactive Materials (2021) 6, 3608-3619.

7. Biodegradable Magnesium Alloys Promote Angio-Osteogenesis to Enhance Bone Repair, Advanced Science (2020).

8. Current status and outlook on the clinical translation of biodegradable metals, Materials Today (2019).

9. Long-term clinical study and multiscale analysis of in vivo biodegradation mechanism of Mg alloy, PNAS (2016).