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“Physicochemical Biomimmetic Materials Lab” 홈페이지에 오신 것을 환영합니다. 본 연구팀은 다양한 의공학적 문제의 해결을 위해 인체 조직의 물리적, 화학적 구조와 기능을 모방하는 고기능성 생체재료를 개발합니다. 의료용 금속을 비롯하여 콜라젠, 피브린 등의 하이드로젤, 고분자 재료 및 이들 간의 하이브리드 재료를 연구하고, 이러한 생체재료들의 물리적 구조 제어와 화학적 기능화를 위한 연구를 수행합니다. 또한, 조직내에서의 물질의 이동현상을 연구함으로써 약물전달, 센서 개발 등 다양한 분야에 응용하고 있습니다.
Welcome to “Physicochemical Biomimmetic Materials Lab” homepage. We develop highly functional biomaterials that mimic the physical and chemical structures and functions of human tissues to solve various biomedical needs. We study biometals, hydrogels(collagen, fibrin, etc.), biodegradable polymers, and hybrid materials between them, and conduct research for the control of physical structures and chemical functionalization of these biomaterials. In addition, we are investigating materials transport issues in tissues for advanced drug delivery and sensor development.
Academic Career
Academic Career
1997 B.S. Seoul National University, Metallurgical Engineering
2002 M.S. Seoul National University, Metallurgical Engineering
2003 Researcher, Korea Institute of Science & Technology (KIST)
2013 Ph.D. University of North Carolina at Chapel Hill, Materials Science
2014 Senior Researcher, Korea Institute of Science & Technology (KIST)
2021 Principal Researcher, Korea Institute of Science & Technology (KIST)
2022 Associate Professor, Korea University of Science & Technology (UST)
Representative Papers
Representative Papers
* : Corresponding Author, #: equal contribution
* : Corresponding Author, #: equal contribution
– Cheol Ho Heo#, Seon Young Bak#, Yonghan Kim, Myoung-Ryul Ok*, and So Yeon Kim* “Development of an integrin αv-based universal marker, capable of both prediction and direction of stem cell fate” Acta Biomaterialia, in press (2023).
– Goeen Jeong, Hyung-Seop Han, Hojeong Jeon, Yu-Chan Kim, Ho Won Jang, and Myoung-Ryul Ok*, “Biodegradable Mg Electrodes for Iontophoretic Transdermal Drug Delivery” Metals and Materials International, in press (2023).
– Hae Won Hwang#, Seongchan Kim#, Hyerim Hwang, Hyung-Seop Han, Hojeong Jeon, Yu-Chan Kim, Hyojin Lee,* Jeong-Yun Sun,* and Myoung-Ryul Ok*, “Spatiotemporal Distribution of Mesoporous Silica Nanoparticles in Tissue-Mimicking Collagen Using Lab-on-a-Chip Technology for Drug Carrier Diffusivity Evaluation” ACS Applied Nano Materials, 5, 9, 12435-12443 (2022).
– Goeen Jeong#, Hae Won Hwang#, Minjung Chae, Seung Hee Hong, Jaeho Park, Yebin Han, Hojeong Jeon, Yu-Chan Kim, Seung-Kyun Kang, Ho Won Jang, Jeong-Yun Sun, and Myoung-Ryul Ok*, “Development of Organic/Inorganic Hybrid Materials for Fully Degradable Reactive Oxygen Species-Releasing Stents for Antirestenosis” Langmuir, 38, 26, 8003-8011 (2022).
– Jung Il Lee#, Ji Hun Park#, Yeong-Rim Kim, Kihak Gwon, Hae Won Hwang, Gayoung Jung, Joo-Yup Lee, Jeong-Yun Sun, Jong Woong Park,* Jae Ho Shin*, Myoung-Ryul Ok*, “Delivery of nitric oxide-releasing silica nanoparticles for in vivo revascularization and functional recovery after acute peripheral nerve crush injury” Neural Regeneration Research, 17, 9, 2043-2049 (2022).
– Jae-Young Bae, Eun-Ji Gwak, Gyeong-Seok Hwang, Hae Won Hwang, Dong-Ju Lee, Jong Sung Lee, Young-Chang Joo, Jeong-Yun Sun, Sang Ho Jun,* Myoung-Ryul Ok,* Ju-Young Kim,* and Seung-Kyun Kang*, “Biodegradable Metallic Glass for Stretchable Transient Electronics” Advanced Science, 2004029 (2021).
– Jimin Park, Hyunseon Seo, Hae Won Hwang, Jonghoon Choi, Kyeongsoo Kim, Goeen Jeong, Eun Shil Kim, Hyung-Seop Han, Yeon-Wook Jung, Youngmin Seo, Hojeong Jeon, Hyun-Kwang Seok, Yu-Chan Kim, Myoung-Ryul Ok*, “Interface Engineering of Fully Metallic Stents Enabling Controllable H2O2 Generation for Antirestenosis” Langmuir, 35, 10, 3634-3642 (2019).
– Jin-Kyung Jeon, Hyunseon Seo, Jimin Park, Soo Ji Son, Yeong Rim Kim, Eun Shil Kim, Jong Woong Park, Woong-Gyo Jung, Hojeong Jeon, Yu-Chan Kim, Hyun-Kwang Seok, Jae Ho Shin, Myoung-Ryul Ok*, “Conceptual Study for Tissue-Regenerative Biodegradable Magnesium Implant Integrated with Nitric Oxide-Releasing Nanofibers” Metals and Materials International, 25, 4, 1098-1107 (2019).
– Seon Yeong Park, Yeon Wook Jung, Si Hyun Hwang, Gun Hyuk Jang, Hyunseon Seo, Yu-Chan Kim, Myoung-Ryul Ok*, “Instrument-Free and Autonomous Generation of H2O2 from Mg–ZnO/Au Hybrids for Disinfection and Organic Pollutant Degradations” Metals and Materials International, 24, 3, 657-663 (2018).
– Jimin Park, Ping Du, Jin‐Kyung Jeon, Gun Hyuk Jang, Mintai Peter Hwang, Hyung‐Seop Han, Kwideok Park, Kwan Hyi Lee, Jee‐Wook Lee, Hojeong Jeon, Yu‐Chan Kim, Jong Woong Park, Hyun‐Kwang Seok, Myoung‐Ryul Ok*, “Mg-corrosion triggered spontaneous generation of H2O2 on oxidized Ti for promoting angiogenesis” Angewandte Chemie International Edition, 54, 14753-14757 (2015).
Researchers & Students
Researchers & Students
Chae, Minjung, MS-PhD student
E-mail ) chemichae@kist.re.kr
Research Area : Surface analysis of biodegradable metals, Cell patch
Choi, Hayoung, MS-PhD student
E-mail ) T22794@kist.re.kr
Research Area : Polymer based hybrid materials, Microneedles, Sputtering
Kim, Hyeon Gyung, Undergraduate student
E-mail ) rhdwngusrud1@naver.com
Research Area : Collagen, Stem Cells
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