What Covid does to the Brain

New Evidence Suggests Long COVID Could Be a Brain InjuryLong-COVID sufferers of brain fog and memory loss exhibit elevated biomarkers consistent with brain injury.

Even mild Covid is linked to brain damage months after illness, scans showThe new British research is the first to reveal striking differences in areas of the brain based on scans taken before and after a coronavirus infection.

Parallel electrophysiological abnormalities due to COVID‐19 infection and to Alzheimer's disease and related dementia Many coronavirus disease 2019 (COVID-19) positive individuals exhibit abnormal electroencephalographic (EEG) activity reflecting “brain fog” and mild cognitive impairments even months after the acut...

Brain infection by SARS-CoV-2: Lifelong consequencesThe WATCH team, founded to elucidate the role played by specialized brain cells called tanycytes in various physiological processes, has been investigating how and where the SARS-CoV-2 virus infects the brain, and some long-term consequences of this neuro-invasion

DU Study Finds History of TBI Likely Worsens Long COVID Symptoms

https://www.du.edu/news/du-study-finds-history-tbi-likely-worsens-long-covid-symptoms

Long-COVID — Concussion AllianceThis page on long-Covid is important because long-Covid has many similarities to concussions and persistent post-concussion symptoms (PPSC). Both long-Covid and concussions involve similar symptoms such as brain fog, trouble concentrating, fatigue, and more. They also result in inflammatory processe

Cognitive dysfunction after covid-19### What you need to know As of March 2023, when the Office for National Statistics stopped collecting data on this condition, 1.879 million individuals had self-assessed as having long covid—symptoms lasting more than 12 weeks following acute covid-19 infection. Of these, the proportion of individuals with symptoms lasting two years or more is around 42%, suggesting a decline in new cases of long covid but a persistence of those with ongoing symptoms.1 Some systematic reviews and meta-analyses have reported that up to a third of such individuals have persistent symptoms of cognitive impairment,23 but estimates vary widely and are complicated by methodological heterogeneity—eg, study size, assessment approach, follow-up duration, and different sampling frames (from self-reported surveys4 to large retrospective matched cohort studies of health records5), as discussed in a recent meta-analysis.6 The pathological underpinnings and potential therapeutic possibilities for cognitive impairment in long covid are also uncertain. The bulk of evidence to date is mechanistic (using basic science, animal models, or human tissue), observational (using longitudinal cohort studies), or hypothetical (reasoning from basic principles); this literature has been well summarised by the RECOVER Consortium.7 Because of the methodological heterogeneity, even when individual studies have been rigorously conducted, it is difficult to know to what extent their findings can be extrapolated and generalised across those with long covid. A few randomised controlled trials of potential treatments (pharmacological and non-pharmacological) …

How covid-19 affects the brainThe coronavirus can cause neurological symptoms. Research is starting to reveal how they occur and if they are treatable, reports Michael Marshall

How Effects on the Brain Can Produce Long COVIDCOVID-19 may be primarily a respiratory illness, but its reach extends far beyond the lungs, with an impact that includes the brain. The neurologic and

COVID-19 infections increase risk of long-term brain problems | Washington University School of Medicine in St. LouisStrokes, seizures, memory and movement disorders among problems that develop in first year after infection

How COVID-19 Affects the Brain, Even Long After an InfectionIt's been linked to brain fog, dementia, stroke, and more.

Does COVID-19 damage the brain? - Harvard HealthMost people who get COVID-19 don't suffer damage to the brain. But some do, and even people who initially get just mild COVID symptoms are vulnerable. COVID's potential to damage the brain is anoth...

COVID-19 and the Nervous System

Mild COVID Linked to Brain Damage: What That Means for YouA study linked mild COVID to brain damage. Read how this fits with known long COVID causes and what it means for effective treatment options.

Long-Term Effects of SARS-CoV-2 in the Brain: Clinical Consequences and Molecular MechanismsNumerous investigations have demonstrated significant and long-lasting neurological manifestations of COVID-19. It has been suggested that as many as four out of five patients who sustained COVID-19 will show one or several neurological symptoms that ...

The Brain and Long Covid2 new studies shed light on persistent neuro-inflammation from even mild infections

Modest cognitive decline occurred with the original virus and with each viral variant, including B.1.1.529 (omicron). As compared with uninfected participants (control), cognitive deficit — commensurate with a 3-point loss in IQ — was evident even in participants who had had mild Covid-19 with resolved symptoms. Participants with unresolved persistent symptoms had the equivalent of a 6-point loss in IQ, and those who had been admitted to the intensive care unit had the equivalent of a 9-point loss in IQ." Study follows

Long Covid and Impaired Cognition — More Evidence and More Work to Do | NEJMEditorial from The New England Journal of Medicine — Long Covid and Impaired Cognition — More Evidence and More Work to Do

Long-term neurologic outcomes of COVID-19 - Nature MedicineIndividuals with COVID-19 are at an increased risk for an array of neurologic disorders at 12 months, even in those who were not hospitalized during the acute phase of the infection.

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COVID-19 Leaves Its Mark on the Brain. Significant Drops in IQ Scores Are Noted.Research shows that even mild COVID-19 can lead to the equivalent of seven years of brain aging

Mounting research shows that COVID-19 leaves its mark on the brain, including with significant drops in IQ scoresTwo new high-profile studies add to the increasingly worrisome picture of how even mild cases of COVID-19 can have detrimental effects on brain health.

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