2023

4. Functionalizing Dendrimers for Targeted Delivery of Bioactive Molecules to Macrophages: A Potential Treatment for Mycobacterium tuberculosis Infection—A Review. 

Sanhueza, C.; Vergara, D.; Chávez-Aravena, C.; Gálvez-Jiron, F.; Chavez-Angel, E.; Alvarez-Castro, A.; Pharmaceuticals 2023, DOI: 10.3390/ph16101428

3. Co-Encapsulation of Curcumin and α-Tocopherol in Bicosome Systems: Physicochemical Properties and Biological Activity. 

Vergara, D.; López, O.; Sanhueza, C.; Chávez-Aravena, C. Villagra, J.; Bustamante, M.; Acevedo, F.; Pharmaceutics 2023, DOI: 10.3390/pharmaceutics15071912

2. Osteoinductive Electrospun Scaffold Based on PCL-Col as a Regenerative Therapy for Peri-Implantitis. 

Sanhueza, C.; Hermosilla, J.; Klein, C.; Chaparro, A.; Valdivia-Gandur, I.; Beltrán, V.; Acevedo, F.; Pharmaceutics 2023, DOI: 10.3390/pharmaceutics15071939

1. In silico approaches to develop new phenyl-pyrimidines as glycogen synthase kinase 3 (GSK-3) inhibitors with halogen-bonding capabilities: 3D-QSAR CoMFA/CoMSIA, molecular docking and molecular dynamics studies. 

Mellado, G.; Espinoza, N.; Garate, J. A.; Morales, C.; Castro-Alvarez, A.; Matos, M. J.; Mellado, M.; Mella, J.; J. Biomol. Struct. Dyn. 2023, DOI: 10.1080/07391102.2023.2172457

2022

12. Structure, Controlled Reelase Mechanisms and Health Benefits of Pectins as Encapsulation Material for Bioactive Food Components. 

R. Morales-Medina, S. Drusch,   F. Acevedo,   A. Castro-Alvarez,   A. Benie,   D. Poncelet,   M. Dragosavac,   M. V. Defain,   P. Löwenstein,   V. Yonaha,   R. Iturralde,   R. G. Peter ,  P. de Vos, Food and Functions 2022, DOI: 10.1039/D2FO00350C 

11. Computational Comparison of the Stability of Iminium Ions and Salts from Enals and Pyrrolidine Derivatives (Aminocatalysts). 

A. M. Costa, A. Castro-Alvarez, D. Fillot, J. Vilarrasa, Eur. J. Org. Chem. 2022, DOI: 10.1002/ejoc.202200627 

10. Synthesis, Antitumor Activity, 3D-QSAR and Molecular Docking Studies of New Iodinated 4-(3H)-quinazolinones 3N-substituted. 

M. Pérez-Fehrmann, V. Kesternich, A. Puelles, V. Quezada, F. Salazar, P. Christen, J. Castillo, J. G. Cárcamo, A. Castro-Alvarez, R. Nelson, RCS Advances 2022, 12, 21340, DOI: 10.1039/D2RA03684C 

9. Cytotoxic Effects on Breast Cancer Cell Lines of Chalcones Derived from a Natural Precursor and Their Molecular Docking Analysis. L. Bustos, C. Echiburú-Chau, A. Castro-Alvarez, B. Bradshaw, M. J. Simirgiotis, M. Mellado, C. Parra, M. Cuellar, Molecules 2022, 27, 4387, DOI: 10.3390/molecules27144387

8. Thermal Rectification and Thermal Logic Gates in Graded Alloy Semiconductors. R.C. Ng, A. Castro-Alvarez, C. M. Sotomayor-Torres, E. Chávez-Ángel, Energies 2022, 15, 4685, DOI: 10.3390/en15134685

7. Design, Synthesis, In Silico Studies and Inhibitory Activity towards Bcr-Abl, BTK and FLT3-ITD of New 2,6,9-Trisubstituted Purine Derivatives as Potential Agents for the Treatment of Leukaemia. J. Bertrand, H. Dostálová, V. Kryštof, R. Jorda, T. Delgado, A. Castro-Alvarez, J. Mella, D. Cabezas, M. Faúndez, C. Espinosa-Bustos, C. O. Salas, Pharmaceutics 2022, 14, 1294, DOI: 10.3390/pharmaceutics14061294

6. Povidone-iodine loaded bigels: Characterization and effect as a hand antiseptic agent. D. Vergara, N. Loza-Rodríguez. F. Acevedo, M. Bustamante, O. López, J. Drug Deliv. Sci. Technol. 2022, DOI: 10.1016/j.jddst.2022.103427

5. Lanthanide SMMs based on Belt Macrocycles: Recent Advances and General Trends. Y. Gil, A. Castro-Alvarez, P. Fuentealba, E. Spodine, D. Aravena, Chem. Eur. J. 2022, DOI: 10.1002/chem.202200336

4. Computational Study of the Stability of Pyrrolidine-Derived Iminium Ions. Exchange Equilibria between Iminium Ions and Carbonyl Compounds. A. M. Costa, V. Cascales, A. Castro-Alvarez, J. Vilarrasa, ACS Omega 2022, DOI: 10.1021/acsomega.1c07020

3. Polyhydroxybutyrate (PHB) Scaffolds for Peripheral Nerve Regeneration: A Systematic Review of Animal Models. M. F. Lezcano, G. Álvarez, P. Chuhuaicura, K. Godoy, J. Alarcón, F. Acevedo, I. Gareis, F. J. Dias, Biology 2022, 11, 706, DOI: 10.3390/biology11050706

2. Spectroscopic and Thermal Characterization of Extra Virgin Olive Oil Adulterated with Edible Oils. E. Chavez-Angel, B. Puertas, M. Kreuzer, R. Soliva Fortuny, R. C. Ng, A. Castro-Alvarez, C. M. Sotomayor Torres, Foods 2022, 11, 1304, DOI: 10.3390/foods11091304

1. Substituted Purines as High-Affinity Histamine H3 Receptor Ligands. C. Espinosa-Bustos, L. Leitzbach, T. Añazco, M. J. Silva, A. del Campo, A. Castro-Alvarez, H. Stark, C. O. Salas, Pharmaceuticals 2022, 15, 573. DOI: 10.3390/ph15050573

2021

8. Review on Sol-Gel Synthesis of Perovskite and Oxide Nanomaterials. D. Navas, S. Fuentes, A. Castro-Alvarez, E. Chavez-Angel, Gels 2021, DOI: 10.3390/gels7040275

7. Convergent synthesis, drug target prediction, and docking studies of new 2,6,9‐trisubstituted purine derivatives. A. Villegas, R. Satheeshkumar, A. Ballesteros-Casallas, M. Paulino, A. Castro, C. Espinosa-Bustos, C. O. Salas, Journal of Heterocyclic Chemistry 2021. DOI: 10.1002/jhet.4368

6. Electrospun fibers loaded with natural bioactive compounds as a biomedical system for skin burn treatment. A review. J. Hermosilla, E. Pastene-Navarrete, F. Acevedo, Pharmaceutics 2021, 13, 2054. DOI: 10.3390/pharmaceutics13122054

5. Development and thermochemical characterization of an antioxidant material based on polyhydroxybutyrate electrospun microfibers. A. Vilchez, F. Acevedo, M. Cea, M. Seeger, R. Navia, International Journal of Biological Macromolecules 2021, 183, 772. DOI: 10.1016/j.ijbiomac.2021.05.002

4. Understanding the Molecular Basis of 5-HT4 Receptor Partial Agonists Through 3D-QSAR Studies. A. Castro-Alvarez, E. Chávez-Ángel, R. Nelson, International Journal of Molecular Sciences 2021, 22, 3602. DOI: 10.3390/ijms22073602

3. Genome-wide metabolic reconstruction of the synthesis of polyhydroxyalkanoates from sugars and fatty acids by burkholderia sensu lato species. N. Alvarez-Santullano, P. Villegas, M. S. Mardones, R. E. Durán, R. Donoso, A. González, C. Sanhueza, R. Navia, F. Acevedo, D. Pérez-Pantoja, M. Seeger, Microorganisms 2021, 9, 1290. DOI: 10.3390/microorganisms9061290

2. One-step electrospun scaffold of dual-sized gelatin/poly-3-hydroxybutyrate nano/microfibers for skin regeneration in diabetic wound. C. Sanhueza, J. Hermosilla, A. Bugallo-Casal, A. Da Silva-Candal, C. Taboada, R. Millán, A. Concheiro, C. Alvarez-Lorenzo, F. Acevedo, Materials Science and Engineering C 2021, 119, 111602. DOI: 10.1016/j.msec.2020.111602

1. Amino-Catalyzed Reactions of Aldehydes with Chiral Nitroalkenes. V. Cascales, H. Carneros, A. Castro-Alvarez, A. M. Costa, J. Vilarrasa, Organic Letters 2021, 23, 651. DOI: 10.1021/acs.orglett.0c03609