Selected Publications

M Chen, A Dahl. (2024) A robust model for cell type-specific interindividual variation in single-cell RNA sequencing data. Nat Comm. web, biorxiv, CTMM python package 

M Sadowski, ..., A Dahl*, N Zaitlen*. (2024) Characterizing the genetic architecture of drug response using gene-context interaction methods. medrxiv, TxEWAS code 

A Dahl* ...  N Cai*. (2023) Phenotype integration improves power and preserves specificity in biobank-based genetic studies of MDD. Nat Gen. web, biorxiv.

D Tang, J Freudenberg, A Dahl. (2023) Factorizing polygenic epistasis improves prediction and uncovers biological pathways in complex traits. AJHG. web, biorxiv, python package, simple R implementation

M Saitou*, A Dahl*, Q Wang, X Liu*. (2022). Allele frequency differences of causal variants have a major impact on low cross-ancestry portability of PRS. medrxiv.

R Border ... A Dahl,  N Zaitlen. (2022). Cross-trait assortative mating is widespread and inflates genetic correlation estimates. Science. web, biorxiv, code

B Sheppard, N Rappoport, P-R Loh, S Sanders, N Zaitlen, A Dahl. (2021) Coordinated Epistasis: A model and test for globally signed epistasis in complex traits. PNAS. web, supp  code, R notebook 

A Dahl, K Nguyen, N Cai, M Gandal, J Flint, N Zaitlen (2020) A robust method uncovers significant context-specific heritability in diverse complex traits. AJHG. web, GxEMM R package, simulation code, UCLA press, ASHG interview

D Steinsaltz*, A Dahl*, K Wachter* (2020) On negative heritability and negative estimates of heritability. Genetics. web

R Hernandez ... A ​Dahl​, N Zaitlen (2019) Singleton Variants Dominate the Genetic Architecture of Human Gene Expression. Nat Gen. web, supp, singher R package

A Dahl ... N Zaitlen (2019) Reverse GWAS: Using Genetics to Identify and Model Phenotypic Subtypes. Plos Gen. web, RGWAS R package, ASHG slides, simulation code

A Dahl ... N Zaitlen (2019) Adjusting for Principal Components of Molecular Phentoypes Induces Replicating False Positives. Genetics. web, simulation code

D Steinsaltz*, A Dahl*, K Wachter* (2018) Statistical properties of simple random-effects models for genetic heritability. EJS. web, simulation code

A Dahl ... J Marchini (2016) Multiple phenotype imputation for genetic studies. Nat Gen. web, supp, phenix R package

A Dahl, V Hore, V Iotchkova, J Marchini (2013). Network inference in matrix-variate Gaussian models with non-independent noise. arXiv, code in phenix package

Reviews/Commentaries

AJ Schork*, RE Peterson*, A Dahl*, N Cai*, Kenneth S Kendler. (2022). Indirect paths from genetics to education. Nat Gen. web

A Dahl, N Zaitlen.  (2020) Genetic Influences on Disease Subtypes. Ann Rev of Genomics and Human Genetics. web