Initiation of Menopausal Hormone Therapy

OBG-Speculum:    2024                       ISSN no.

Vol -2, Issue -1  

Dr. Amrita Jaipuriyar

Menopausal hormone therapy(MHT) options need to be selected cautiously for every woman, which is based on many factors like age, symptomatology, early or late menopause transition, uterus in situ or hysterectomy, habits, medical disorders etc. Maximum benefit of MHT is between 40-55 years of age.

At time of deciding about MHT the most important basic aspect is to know where not to give MHT i.e., contra-indications

Contraindications of MHT

·                ➢ history, suspicion or recent management of Breast carcinoma –

o                 invasive breast carcinoma, premalignant changes of breast (atypical ductal hyperplasia, lobular neoplasia) and a ductal carcinoma in situ.

·                ➢ Undiagnosed vaginal bleeding

o                 as a sign of endometrial or endocervical carcinoma

·                ➢ H/o Estrogen-dependent carcinomas

o                 endometrial carcinoma, breast carcinoma, endometrial stromal sarcoma

·                ➢ Active hepatic disease

·                ➢Venous Thromboembolic disease

o                 pulmonary embolism, thrombosis deep veins

·                ➢ Active arterial thromboembolism

o                 angina pectoris, Coronary Artery disease, Myocardial infarction, stroke

·                ➢ Known intolerance to the preparation.

By history, examination and basic investigation basis if women does not belong to any of above mentioned contraindication she can be prescribed MHT which should be as follows.