Prof. Dr. Filippo Doria

Filippo was born in Voghera in 1982. After receiving his Scientific High School Diploma from the Liceo Scientifico Statale G. Galilei in Voghera, he obtained his Master's Degree in Chemistry from the University of Pavia. In 2006 he started his doctoral studies in the same university with Prof. M. Freccero, focusing his doctoral research on the targeting of nucleic acids’s secondary structures and the development of photoinduced processes. During his Ph.D. journey, he spent one year as an exchange visiting student at the University of London, in the group of Prof. S. Neidle at the Cancer Research UK Biomolecular Structure Group. After his graduation in 2009, he became a Postdoctoral Researcher in the group of Prof. M. Freccero, and started his independent career in 2014. In 2015 he worked in the Instituto de Parasitologia y Biomedicina with Prof. Dr. Juan Carlos Morales-Sanchez in Granada as a Visiting Scientist. In 2018 he became Fixed-time Researcher (RTDb) at the University of Pavia, and since 2022 he is an Associate Professor at the same institution.

His research interests rely on the synthesis of selective multifunctional ligands, targeting DNA/RNA secondary structures in human telomeres, oncogene promoters, viruses, and bacteria for theranostic applications, development of (i) selective turn-on fluorescent probe, (ii) selective ligands targeting different G4 structures, (iii) effective transient and activatable reactants (quinone methides, reactive oxygen species (ROS), carbenes and nitrenes) targeting DNA secondary structures, (iv) a library of XNAs, resulting from the conjugation of G4s ligand to chiral peptide nucleic acids (PNAs) or locked nucleic acids (LNAs).

Throughout his academic career, he supervised many Bachelor and Master students, Ph.D. students and Postdocs.