Our lab is located at the ground floor of the Department of Chemistry - Organic Chemistry Section in the University of Pavia, immersed in the setting of the city. We have at our disposal one main synthetic lab, two instrument rooms, and several rooms that feature shared Departmental equipment.
Organic Synthesis Lab
The main synthesis laboratory is equipped with four high-efficiency fume hoods and a dedicated air recirculation system connected to the external environment, ensuring safe and controlled working conditions. The lab hosts a variety of instrumentation including two analytical balances, a precision balance, a UV lamp, six rotary evaporators with glycol chillers, a microwave synthesizer, two Biotage Isolera systems (Selekt and Isolera One) for flash purification, an ultrasonic bath, and four refrigerators for the storage of reagents and products. Ventilated cabinets for solvents and chemical reagents are also available to ensure proper containment and safety.
Instrument Room
One of the instrument rooms is dedicated to spectroscopic and preliminary bio- and photophysical investigations. It is equipped with UV-Vis spectrophotometers and fluorimeters suitable for a wide range of absorbance and fluorescence-based assays. The room provides a controlled environment for the characterization of compounds, monitoring of photophysical behavior, and basic studies on molecular interactions in solution.
Agilent Cary 60 UV-Vis Spectrophotometer
Agilent Cary Eclipse Spectrofluorometer
Agilent AriaMx Real-time PCR System
Multiwavelength Rayonet system with black chamber
Multiwavelength irradiation lamps
Purification Room
Another dedicated room hosts our purification systems and peptide synthesis platform. It includes two preparative HPLC systems and one analytical HPLC for compound purification and quality control. A modern freeze dryer is available for solvent removal and product stabilization. The room also features a state-of-the-art automated peptide synthesizer, enabling the efficient production of custom peptides for a variety of applications.
Agilent 1260 Infinity Preparative HPLC
Agilent 1260 Infinity Analytical HPLC w/autosampler
Agilent 1260 Infinity II Preparative HPLC w/autosampler
CEM LibertyBlue 2.0 Peptide Synthesizer
Shared Instruments
In addition to our dedicated laboratory spaces, we have access to several Departmental instrument rooms shared with other research groups. These facilities include high-field NMR spectrometers, as well as LC-MS and GC-MS systems for advanced structural and analytical characterization. The shared instrumentation supports a wide range of applications, from small molecule analysis to complex mixtures and biomolecular studies.
Bruker Avance 400MHz NMR w/autosampler
Agilent InfinityLab 1260 II Single Quadrupole LC/MS w/autosampler
Jasco UHPLC/Thermo LTQ-XL LC/MS Linear Ion Trap system
Thermo Trace1300/ISQ7000 GC/MS Single Quadrupole system w/autosampler