DARMA
Microbial Diversity, Adaptation and Resilience
Universidad Nacional de Colombia
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Description
DARMA is a research incubator group formed by undergraduate and graduate students from Universidad Nacional de Colombia, which seeks through journal clubs, scientific presentations and development of research projects, to strengthen the areas of study of the evolution and diversity of microorganisms in the country.
Our methodologies within the incubator seek the collective construction of knowledge, mainly to generate the conceptual, technical and scientific bases to address research questions in the areas of evolution and microbial ecology. Through these questions, experimental design, and analysis of results we seek to approach nature and learn from a fragment of this reality.
Skills to be acquired during the incubator
Strengthen the fundamental concepts of diversity analysis such as:
Strengthening the basic concepts of molecular evolution:
- Concepts of preparation, sequencing and analysis of molecular markers.
- Characterization of diversity through phylogenetic reconstruction.
- Alpha and beta diversity indices.
- Visualization and interpretation of scientific data.
- Multivariate and ordination analysis to relate samples.
- Correlation analysis between environmental variables and taxonomic groups (e.g. Mantel test).
- Inference of microorganism interactions by means of correlation networks.
Strengthening the basic concepts of molecular evolution:
- Concepts of evolution, genetic drift, natural selection.
- Similarities and differences in the evolution of bacteria and macroorganisms.
- Forces dominating bacterial genomic evolution.
- Positive selection pressure (diversifying).
- Negative (stabilizing) selection pressure.
- Effect of selection on genome organization and the functioning of the genetic machinery.
Disclosure for the formation of research incubators
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