Publications

X Wu, H Guo, H Gao, Y Li, X Hu, MA Kowalke, YX Li, Y Wei, J Zhao, ...Peptide targeting improves the delivery and therapeutic index of glucocorticoids to treat rheumatoid arthritis. Journal of Controlled Release 368, 329-343

H Guo, J Guan, X Wu, Y Wei, J Zhao, Y Zhou, F Li, HB Pang. Peptide-guided delivery improves the therapeutic efficacy and safety of glucocorticoid drugs for treating acute lung injury. Molecular Therapy 31 (3), 875-889

Wu X, Guo H, Zhao J, Wei Y, Li YX, Pang HB. Identification of an ALK-2 Inhibitor as an Agonist for Intercellular Exchange and Tumor Delivery of Nanomaterial. Advanced Therapeutics. https://doi.org/10.1002/adtp.202200173

Li YX, Wang N, Hasan H, Pang HB. Co-administration of Transportan Peptide Enhances the Cellular Entry of Liposomes in the Bystander Manner Both In Vitro and In Vivo. Molecular Pharmaceutics, 2022, 19, 11, 4123–4134

Wei Y, Chen H, Li YX, He K, Yang K, Pang HB. Synergistic entry of individual nanoparticles into mammalian cells driven by free energy decline and regulated by their sizes. ACS Nano, 16, 4, 5885-5897

X Wu, T Tang, Y Wei, KA Cummins, DK Wood, HB Pang. Extracellular vesicles mediate the intercellular exchange of nanoparticles. Advanced Science 9 (7), 2102441

Kejie He, Yushuang Wei, Zhihong Zhang, Haibo Chen, Bing Yuan, Hong-Bo Pang, Kai Yang. Membrane-curvature-mediated co-endocytosis of bystander and functional nanoparticles. Nanoscale.   

Li X, YX Li, Y Wei, R Zhong, L Li, HB Pang. Transportan Peptide Stimulates the Nanomaterial Internalization into Mammalian Cells in the Bystander Manner through Macropinocytosis. Pharmaceutics 13 (4), 552

Guan J, Guo H et al.  iRGD-liposomes enhance tumor delivery and therapeutic efficacy of antisense oligonucleotide drugs against primary prostate cancer and bone metastasis. Advanced Functional Materials. Apr 2021. 

Li X, Pang HB. Macropinocytosis as a cell entry route for peptide-functionalized and bystander nanoparticles.  Journal of Controlled Release. 2021 Jan 10; 329: 1222-1230.

Tang T, Wei Y, Yang Q, Yang Y, Sailor MJ and Pang HB. Rapid chelator-free radiolabeling of quantum dots for in vivo imaging.  Nanoscale. 2019. DOI: 10.1039/c9nr08508d.

Wei Y, Tang T, Pang HB. Cellular internalization of bystander nanomaterial induced by TAT-nanoparticles and regulated by extracellular cysteine. Nature Communications. 2019 Aug 13;10(1):3646.

Tang T, Wei Y, Kang J, She ZG, Kim D, Sailor MJ, Ruoslahti E, Pang HB. Tumor-specific macrophage targeting through recognition of retinoid X receptor beta.J Control Release. 2019 May 10;301:42-53. doi: 10.1016/j.jconrel.2019.03.009. 

Kim B*, Pang HB*, Kang J, Park JH, Ruoslahti E, Sailor MJ. Immunogene therapy with fusogenic nanoparticles modulates macrophage response to Staphylococcus aureus.  Nat Commun. 2018 May 17;9(1):1969. doi: 10.1038/s41467-018-04390-7. *Co-first authors.

She ZG, Hamzah J, Kotamraju VR, Pang HB, Jansen S, Ruoslahti E. Plaque-penetrating peptide inhibits development of hypoxic atherosclerotic plaque. J Control Release. 2016 Sep 28;238:212-220. doi: 10.1016/j.jconrel.2016.07.020. Epub 2016 Jul 15.

Pang HB*, Braun GB, Ruoslahti E*. Neuropilin-1 and heparan sulfate proteoglycans cooperate in cellular uptake of nanoparticles functionalized by cationic cell-penetrating peptides. Sci Adv. 2015 Nov 6;1(10):e1500821. doi: 10.1126/sciadv.1500821. eCollection 2015 Nov. *Co-corresponding author.

She ZG, Chang Y, Pang HB, Han W, Chen HZ, Smith JW, Stallcup WB. NG2 Proteoglycan Ablation Reduces Foam Cell Formation and Atherogenesis via Decreased Low-Density Lipoprotein Retention by Synthetic Smooth Muscle Cells. Arterioscler Thromb Vasc Biol. 2016 Jan;36(1):49-59. doi: 10.1161/ATVBAHA.115.306074. Epub 2015 Nov 5.

Pang HB, Braun GB, Friman T, Aza-Blanc P, Ruidiaz ME, Sugahara KN, Teesalu T, Ruoslahti E. An endocytosis pathway initiated through neuropilin-1 and regulated by nutrient availability. Nat Commun. 2014 Oct 3;5:4904. doi: 10.1038/ncomms5904.

Braun GB, Friman T, Pang HB, Pallaoro A, Hurtado de Mendoza T, Willmore AM, Kotamraju VR, Mann AP, She ZG, Sugahara KN, Reich NO, Teesalu T, Ruoslahti E. Etchable plasmonic nanoparticle probes to image and quantify cellular internalization. Nat Mater. 2014 Sep;13(9):904-11. doi: 10.1038/nmat3982. Epub 2014 Jun 8. 

Pang HB, Braun GB, She ZG, Kotamraju VR, Sugahara KN, Teesalu T, Ruoslahti E. A free cysteine prolongs the half-life of a homing peptide and improves its tumor-penetrating activity. J Control Release. 2014 Feb 10;175:48-53. doi: 10.1016/j.jconrel.2013.12.006. Epub 2013 Dec 15.