Embedded Files
Phase I Publications and Preprints
Kayrouz, Colby S., Jenna L. Manske, Martí Garçon, Isaac A. Joyner, Yuehan Wang, Yifei Ge, Alexandra E. Paton, Alison R. H. Narayan, and John F. Hartwig. 2025. “Site- and Stereoselective Enzymatic Halogenation of Terpenoids by Substrate Anchoring and Protein Engineering.” ChemRxiv. Submitted to Nat. Chem.
Access to Enantioenriched Atropisomers through Biocatalytic Deracemization
Roos, Casey, S. Luke Schulert, Lara Zetzsche, Spencer McMinn, Angela Cheong, Eunjae Shim, Eugene Kwan, and Alison Narayan. 2025. “Access to Enantioenriched Atropisomers through Biocatalytic Deracemization.” ChemRxiv.
Photobiocatalytic Enantioselective C(sp3)–H Acylation Enabled by Thiamine-Dependent Enzymes via Intermolecular Hydrogen Atom Transfer
Lu, Yen-Chu, Ronald Adukure, Satyajit Roy, Derek Chien, Matthew McGill, Karl Scheidt, and Rudi Fasan. 2024. “Photobiocatalytic Enantioselective C(sp3)–H Acylation Enabled by Thiamine-Dependent Enzymes via Intermolecular Hydrogen Atom Transfer.” ChemRxiv. In revision at JACS.
Highly Enantioselective Construction of Oxazolidinone Rings via Enzymatic C(sp3)–H Amination
Majhi, Jadab, Satyajit Roy, Anwita Chattopadhyay, and Rudi Fasan. 2024. “Highly Enantioselective Construction of Oxazolidinone Rings via Enzymatic C(sp3)–H Amination.” ACS Catalysis 15 (2): 809–16.
Generation of Connections between Protein Sequence Space and Chemical Space to Enable a Predictive Model for Biocatalysis
Paton, Alexandra, Daniil Boiko, Jonathan Perkins, Nicholas Cemalovic, Thiago Reschützegger, Gabe Gomes, and Alison Narayan. 2024. “Generation of Connections between Protein Sequence Space and Chemical Space to Enable a Predictive Model for Biocatalysis.” ChemRxiv. In revision at Nature.
Autonomous Chemical Research with Large Language Models
Boiko, Daniil A., Robert MacKnight, Ben Kline, and Gabe Gomes. 2023. “Autonomous Chemical Research with Large Language Models.” Nature 624 (7992): 570–78.
Enabling Broader Adoption of Biocatalysis in Organic Chemistry
Romero, Evan O., Anthony T. Saucedo, José R. Hernández-Meléndez, Di Yang, Suman Chakrabarty, and Alison R. H. Narayan. 2023. “Enabling Broader Adoption of Biocatalysis in Organic Chemistry.” JACS Au 3 (8): 2073–85.
Research Updates
Fasan and Scheidt groups collaborate to derive a new photobiocatalytic strategy
Fasan and Scheidt groups collaborate to derive a new photobiocatalytic strategy
Congratulations to Drs. Rudi Fasan and Karl Scheidt, and their associated labs, for their latest preprint focused on enantioselective C(sp3)–H acylation of an organic substrate. The details can be found here.
The Fasan group publishes new method for synthesis of intermediates
The Fasan group publishes new method for synthesis of intermediates
In their recent publication in ACS Catalysis, the Fasan group demonstrates a biocatalytic method for synthesizing enantioenriched oxazolidinones. You can find the publication here.
Narayan group unveils new pre-print on synthesizing enantiopure materials
Narayan group unveils new pre-print on synthesizing enantiopure materials
Dr. Alison Narayan's lab has just released their most recent work on synthesizing enantioenriched atropisomers. Casey Roos, a C-CES trainee, is first author. Read about this exciting research here.
December 31, 2024
December 27, 2024
February 11, 2025
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