The DVJ lab lacks a method of applying in vivo axial stretch and radial pressure to a blood vessel in situ while allowing for imaging of collagen fiber orientation, which could characterize the structural changes caused by PAH.
The main goal is to provide a device which can hold a PA at a 40% axial stretch (for the PAs we are using, this is ~1.6 mm - 2.4 mm) and a constant set radial pressure to allow imaging of collagen fibers under an MPM, mimicking in situ conditions.
Our team used a gantt chart to keep track of our progress over the 7 months of working on this project. We subdivided into two teams to streamline the design process. Subproject 1, axial stretch: Helen Song, Jacqueline Fontanares. Subproject 2, radial pressure: Ethan Winter, Melvyn Hsu.