Our Research

APERSU Research Agenda

We conduct:

Current Projects

Enhancing the Use of Routinely Collected PROMs in the Health System

Exploring Validity of the EQ-5D-5L in Indigenous People of Canada
This project aims to investigate the validity of the EQ-5D-5L for Indigenous people in Canada. A systematic review has been completed. The next phase uses qualitative description and think aloud exercises to explore both face and content validity, and conceptual feasibility and interpretation of stated choice and health valuation tasks among Indigenous people.

This mixed-methods study examines the validity of quality of life measures in young children with juvenile idiopathic arthritis.

Using and presenting EQ-5D in patient decision aids (hip/knee arthroplasty)
This study will examine the effectiveness of an online, individualized patient decision aid for total knee replacement surgery to improve the quality of patient choices. The decision aid will be implemented across Alberta through the Alberta Bone and Joint Health Institute (ABJHI). This individualized decision aid is innovative in that it enables patients to consider individuals with similar characteristics, using basic demographic information and a patient-reported outcome measure (PROM) (i.e., the EQ-5D), and compare the likelihood of surgical outcomes to their unique situation.

EuroQol Data for Assessment of Population Health Needs and Instrument Evaluation (EQ-DAPHNIE):
The overall aim of the EQ-DAPHNIE project is to create research infrastructure for the EuroQol Group that would support future research projects which have specific research objectives/questions. The breadth of potential research topics would be characterized under two broad domains: 1) Population health status (e.g., develop country-specific population norms, social determinants of health and population health inequities); 2) Comparative performance and validation of instruments (e.g., EQ-HWB vs. EQ-5D-5L).

Evaluation of routinely Measured PATient reported outcomes in HemodialYsis care (“EMPATHY”) Trial:
This project aims to determine the effects of routine measurement and reporting to care providers of patient-reported outcome measures (PROMs) namely the modified Edmonton Symptom Assessment Scale – renal (mESASr) and/or the EQ-5D-5L on patient reported experience, particularly patient-clinician communication, for patients with chronic kidney disease (CKD) undergoing hemodialysis. The EMPATHY Trial will be a large, multi-center cluster randomized trial, involving up to 80 dialysis units in Ontario, Alberta and BC. The EMPATHY Trial is one project under the umbrella of a large, pan-Canadian research network known as CAN-SOLVE CKD.

Past Projects

Properties of the EQ-5D-5L in the Canadian Population: Minimal Important Difference and Comparative Performance with other Measures in Large Scale Health Applications:
This program of research has two general aims: 1) to compare the measurement properties of the EQ-5D instruments (3- and 5-level) with other generic and disease-specific measures of health status and health-related quality of life, with particular attention to the individual dimensions of the EQ-5D; and 2) to generate estimates for a minimal important difference (MID) for the EQ-5D-5L index score.

The use and measurement properties of EQ-5D in vulnerable populations: A systematic review of the literature: The objective of this review is to identify, summarize and appraise the literature on the use and measurement properties of EQ-5D instruments in socially vulnerable populations, i.e. populations who are at risk of adverse health outcomes due to the socioeconomic environment and resources; including but not limited to homelessness, substance abuse among others.

PROMs in Primary Care Networks in Alberta: An end-user perspective: APERSU’s team collaborated with the Primary Care Measurement Capacity Initiative (MCI) group led by Dr. Scott Oddie with Alberta Health Services, on a project that explored the use of PROMs in primary care networks (PCNs) in Alberta, and identified the facilitators and barriers to PROMs implementation in this setting.The scientific advisory committee identified four key areas of research that will define APERSU’s research agenda.