5. Other demonstration

5.1. Representative query results in the pipeline of the Drug-SNPing

Fig. 65. Representative query results in the pipeline of Drug-SNPing. A: Drug information for input. a1) Hyperlinking to the DrugBank. a2) DrugBank information to the Drug-SNPing. B: Query results for b1) drug targets, b2) metabolizing enzymes, b3) drug transporters, and b4) drug carriers. C: Condition setting for the on-line analysis of STRING-based protein interaction mining and HapMap-based tagSNP retrieval. c1) TagSNP and c2) preferred name selections for analyses. D: Query results for interactive genes/corresponding tagSNPs and genotyping information. E: Query results for more or less STRING interactions in an interactive way. e1) SNP query setting for dbSNP in NCBI, e2) HapMap tagSNPs, and e3) Interactive protein interaction for SNPs or tagSNP selection were included. Results of red arrows in Fig. 65A, B, C, and D are shown in Fig. 65B, C, D, and E, respectively.

5.2. Representative outputs for SNP genotyping information in the Drug-SNPing

Fig. 66. Representative outputs for SNP genotyping information in Drug-SNPing. A: Natural primers for rs2740171. B: Mutagenic primers for rs1051740. SNP genotyping information such as a1: SNP fasta sequence; a2/b1: TaqMan probe from SNP500Cancer/NCBI, a3/b2: natural/mutagenic RFLP primers, and a4/b2: restriction enzymes for natural/mutagenic RFLP primers are shown.

Return