Publications

Luo, Y.B., and Liu, S.T. (2021) Further Reading | The Mitotic Checkpoint, Editor(s): Joseph Jez, Encyclopedia of Biological Chemistry III (Third Edition), Elsevier, 2021, Pages 484-495, ISBN 9780128220405, https://doi.org/10.1016/B978-0-12-819460-7.00324-8. (https://www.sciencedirect.com/science/article/pii/B9780128194607003248) Book chapter; Review.

*Sreemita, M. and Liu, S.T. (2020) Cell Division Symmetry Control and Cancer Stem Cells. Review article. AIMS Molecular Science. 2020, 7(2): 82-98. doi: 10.3934/molsci.2020006.

Liu, S.T., Chan, G. and Li, W. (2019) Editorial: Non-cell cycle functions of cell cycle regulators. Front. Cell Dev. Biol. 7:122. doi: 10.3389/fcell.2019.00122. PMCID: PMC6610303; PMID: 31316983

Rashid, M., Mazur, T., *Ji, W., Liu, S.T. and Taylor, W.R. (2018) Analysis of the role of GSK3 in the mitotic checkpoint. Scientific Reports. 2018 Sep 24;8(1):14259. doi: 10.1038/s41598-018-32435-w. PMID: 30250048

Luo, Y.B., Ahmad, E., and Liu, S.T. (2018) MAD1: Kinetochore Receptors and Catalytic Mechanisms. Front. Cell Dev. Biol. | doi: 10.3389/fcell.2018.00051

*Ji, W., Luo, Y.B., Ahmad, E., and Liu, S.T. (2018) Direct interactions of Mitotic Arrest Deficient 1 (MAD1) domains with each other and MAD2 conformers are required for mitotic checkpoint signaling. J Biol Chem. 293(2):484-496. doi: 10.1074/jbc.RA117.000555. Epub 2017 Nov 21. PMID:29162720.

Liu, S.T. and *Zhang, H. (2016) The mitotic checkpoint complex (MCC): looking back and forth after 15 years. AIMS Molecular Science, 3(4): 597-634. Review for a special issue on Cell Signaling and Signal Transduction. doi: 10.3934/molsci.2016.4.597 [link]

*Ji, W., *Arnst, C.A., *Tipton, A.R., Bekier, M.E. 2^nd, Taylor, W. R., Yen, T.J. and Liu, S.T. (2016) OTSSP167 abrogates mitotic checkpoint through inhibiting multiple mitotic kinases. PLOS ONE. 11(4): e0153518. https://doi.org/10.1371/journal.pone.0153518PMID: 27082996. [link]

[Unsolicited comments on the above paper:

http://blogs.sciencemag.org/pipeline/archives/2017/03/27/melk-is-not-a-cancer-target-surprise

“There was a report last year that the compound could well be hitting other kinase targets at the concentrations that it reaches in vivo, and that these might be responsible for some of its effects.”

https://www.the-scientist.com/daily-news/rethinking-a-cancer-drug-target-31777

“…pointed to two recent studies with corroborative findings: one suggesting that OTS167 acts upon multiple kinases…”]

Eytan, E., *Wang, K., Miniowitz-Shemtov, S., Sitry-Shevah, D., Kaisari, S., Yen, T.J., Liu, S.T. and Hershko, A. (2014) Disassembly of mitotic checkpoint complexes by the joint action of the AAA ATPase TRIP13 and p31comet. Proceedings of National Academy of Sciences USA. 111 (33): 12019-24. PMID: 25092294. [link]

*Wang, K., Sturt-Gillespie, B., Hittle, J.C., Macdonald, D., Chan, G.K., Yen, T. J. and Liu, S.T. (2014) Thyroid Hormone Receptor Interacting Protein 13 (TRIP13) AAA-ATPase is a Novel Mitotic Checkpoint Silencing Protein. Journal of Biological Chemistry. 288(49):35149-58. PMID: 24151075. [link]

[Unsolicited comments on the above two papers from other scientists:

http://elifesciences.org/content/4/e08283

“The key to gaining a molecular understanding was the characterization of two proteins—

TRIP13/PCH2 and p31^comet —that were known to be involved in disassembling the effector complex formed by closed Mad2 and Cdc20 (Eytan et al., 2014; Wang et al., 2014).”

http://link.springer.com/article/10.1007%2Fs00412-015-0516-y

“Excitingly, recent work has also implicated a role for Pch2^TRIP13 in wiring of the checkpoint that guards the metaphase-to-anaphase transition.”]

Liu, S.T. (2014) Kinetochore: Structure, Function and Evolution (version 2.0), In: Encyclopedia of Life Sciences (ELS). http://www.els.net/ [DOI: 10.1002/9780470015902.a0006237.pub2]. Review.

Ma, J., Zhang, L., *Tipton, A.R, Wu, J., Messmer-Blust, A., Philbrick, M., Qi, Y., Liu, S.T., Liu, H., Li, J. and Guo, S. (2014) Structural and Functional Analysis of the Related Transcriptional Enhancer Factor-1 (RTEF-1) and Nuclear Factor Kappa B (NF-κB) Interaction. American Journal of Physiology-Heart and Circulatory Physiology. 306(2):H233-42. PMID: 24213609 [link ]

*Tipton, A.R., *Ji, W., Sturt-Gillespie, B., Bekier, M. E. 2nd, *Wang, K., Taylor, W. R. and Liu, S.T. (2013) Monopolar Spindle 1 (MPS1) Kinase Promotes Production of Closed MAD2 (C-MAD2) Conformer and Assembly of the Mitotic Checkpoint Complex. Journal of Biological Chemistry. 288(49):35149-58. PMID: 24151075. [link ]

*Tipton, A.R., *Wang, K., **Oladimeji, P., **Sufi, S., Gu, Z. and Liu, S. T. (2012) Identification of novel mitosis regulators through data-mining with human centromere/kinetochore proteins as group queries. BMC Cell Biology. 2012, 13:15. PMID:22712476; PMCID: PMC3419070. [link] (Editor’s Picks)(Highly Accessed) (2012 June Image Highlight) (among MOST VIEWED list)

*Tipton, A.R., **Tipton, M., Yen, T. J. and Liu, S.T. (2011) Closed MAD2 (C-MAD2) is selectively incorporated into the mitotic checkpoint complex (MCC). Cell Cycle. 10(21): 3740-50. PMID: 22037211. [link]

*Tipton, A.R., *Wang, K., **Link, L., Bellizzi, J.J., Huang, H. Yen, T. J. and Liu, S.T. (2011) BUBR1 and closed MAD2 (C-MAD2) interact directly to assemble a functional Mitotic Checkpoint Complex (MCC). Journal of Biological Chemistry. 286(24):21173-9. PMID: 21525009; PMCID: PMC3122179. [link]

[Unsolicited comments on this paper from other scientists:

http://elifesciences.org/content/4/e07367

“Tipton et al. (2013; JBC 286) were the first authors to demonstrate the interaction of BubR1 with C-MAD2 that p31comet interferes with.”

https://facultyopinions.com/prime/14263964

“I would like to point out that the structure shows that Mad2 and Mad3 (the ortholog of human BubR1) interact directly within the mitotic checkpoint complex (MCC), confirming previous data {1}.” ]

Bazeley, P.S., Nestor-Kalinoski, A.L., Ways, J., Liu, S.T., Ramdath, R.S., Matsui, S. and Allison, D.C. (2011) A Model for Random Genetic Damage Directing the Selection of Diploid or Aneuploid Tumors. Cell Proliferation, 44(3):212-23.

Liu, S.T., Allison, D.C., and Nestor-Kalinoski, A. L. (2010) Chromosomes during Cell Division, In: Encyclopedia of Life Sciences (ELS). John Wiley & Sons, Ltd. Chichester. DOI: 10.1002/9780470015902.a0005770.pub2. Review.

Liu, S.T. and Yen, T. J. (2008) The kinetochore as target for cancer drug development. In “The Kinetochore: from Molecular Discoveries to Cancer Therapy" (Eds. De Wulf P., and Earnshaw W.C.). Springer Publ. New York. Book Chapter. Review.