ABL1
V-abl Abelson murine leukemia viral oncogene homolog 1 also known as ABL1 is a protein which in humans is encoded by the ABL1 gene located on chromosome 9.
Mouse Knockout
Phenotype
Tissues Affected
Literature Cited
Human Diseases
Summary of Mutations
Phenotype
t(9;22) translocation results in fusion with the BCR gene
Chronic myelogeneous leukemia (CML), acute
lymphoblastic leukemia (ALL), myelogenous leukemia
(AML) (de Klein et al., 1982; Heisterkamp et al., 1983)
Specificity
Abl
[pY] [E/T/M] [N/E/D] [P/V/L]
(Songyang et al., 1993)
Peptide arrays (Coming Soon!)
Structures
