CPAP vs Mandibular Advancement Devices and Blood Pressure in Patients With Obstructive Sleep Apnea - A Systematic Review and Meta-analysis

Post date: Dec 13, 2015 8:39:13 AM

Obstructive sleep apnea is associated with higher levels of blood pressure (BP), which can lead to increased cardiovascular risk. The objective of the review was to compare the association of continuous positive airway pressure (CPAP), mandibular advancement devices (MADs), and inactive control groups (placebo or no treatment) with changes in systolic BP (SBP) and diastolic BP (DBP) in patients with obstructive sleep apnea.

Conclusions and Relevance Among patients with obstructive sleep apnea, both CPAP and MADs were associated with reductions in BP. Network meta-analysis did not identify a statistically significant difference between the BP outcomes associated with these therapies.

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