M2E or MEM

The M2E (meta-omics and microbial ecosystems) or MEM (Méta-omiques et écosystèmes microbiens) flagship aims to generate new contacts within the INRA institute. Details are available on https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/407267-f2dba-resource-metaprogramme-mem-2016-2020-short-version-en.pdf

One of the four thematic groups discuss all the techniques and concepts around microbial ecology applied to anaerobic digestion during monthly visioconferences.

When relevant, the information is reported to the head of the M2E flagship (E.Maguin / S. Dequin).

THE SCIENTIFIC TALKS (note that the scientific talks can be recorded and shared if the author agrees)

16 Apr 2018, 15h-16h : Timothy Johnson (Purdue University) , Antibiotic resistance genes in Swine

25 May 2018, NEM Meeting in Narbonne. See programm here.

6 July 2018, 15h15-16h : Sylvain Billiard (Lille University), Interaction proie/prédateur

21 September 2018, 15h15-16h : Anne Siegel, Metabolism Using Genome-Scale Reconstruction, Modeling, and Testing

23rd November 2018, 15h : Thomas Rilling : coalescence (http://www.bcp.fu-berlin.de/en/biologie/arbeitsgruppen/botanik/ag_rillig/index.html)

May 2018: NEM Meeting in Nantes will occur on the 21th and 22 may 2019. The local organisers will be patricia and catherine.

THE PUBLIC ATTENDING THE MEETING ON A REGULAR BASIS

Jerome Hamelin (first name dot surname at inra dot fr) works in Narbonne on the ecological engineering of microbial communities in bioprocesses (anaerobic digestion, wastewater treatment). He is interested in the role of microbial interactions and community assembly processes in shaping the ecosystem functioning. More information available here. [lien hypertexte] https://www6.montpellier.inra.fr/narbonne/Personnel2/Les-chercheurs/Jerome-HAMELIN

Dr Jean-Paul Lallès (jean-paul.lalles@inra.fr) belongs to the Human Nutrition Division of INRA and is located in Rennes, France. His background is agriculture engineering, biochemistry and immunology. His research has been focused on (protein) nutrition and gut (patho)physiology in farm animals, including the pig as a model for human. His present interests include host-microbiota crosstalk in the context of host intestinal defense systems and its nutritional modulation.

Keywords : gut, nutrition, microbiota, defense systems, innate immunity

Keywords: gut microbiota transplants, pigs, rabbits, Illumina, feed efficiency, antibiotic resistance

Olivier Zemb (olivier.zemb ta inra dot fr) works in Toulouse on animal gut microbes (rabit, pigs and broilers). He uses 16S sequencing, high-throughput qPCR with multivariate statistics together with fecal transplantation of complex communities.

Philippe Gérard ( first name dot surname at inra dot fr) works in Jouy-en-Josas, France. He investigates the role of the gut microbiota in metabolic diseases (obesity, NAFLD…) mainly using germ- free rodent models, gut microbiota transplants and nutritional modulation of the intestinal ecosystem.

Keywords: obesity, liver diseases, germ-free animal models, gut microbiota transplants, high fat high sugar diets

Eric Neyraud (eric.neyraud at inra dot fr) works on saliva , taste and bacterial metabolites. He is also involved in the Holonbiont theme taking place within the INRA M2E flagship.

Sophie Gaudriault (sophie.gaudriault at umontpellier.fr) works in Montpellier, France. She is bacteriologist and investigates interactions between invertebrates (nematodes and insects) and entomopathogenic bacteria, some of which being resident in the animal guts. She is interested in the pathobiome, i.e. the pathogenic bacteria in their biotic environment, and in the modulation of the infectious process by the pathobiome. She is also interest in adaptation and evolution of virulence functions in the view of the holobiont concept, a prioritary theme identified by the INRA M2E flagship.Keywords: bacteria-invertebrate-pathogenic interactions-pathobiome

Muriel Mercier-Bonin (Muriel.Mercier-Bonin@inra.fr) works in Toulouse, France. She investigates the mucus/microbiota crosstalk in the gut by focusing on mucus homeostasis, its disruption through chemical and psychological stresses, and its restoration using nutritional bioremediation strategies (beneficial bacteria).Keywords: mucus/microbiota crosstalk, gut barrier, food xenobiotics, chronic psychological stress, beneficial bacteria

Dr Pascale MOSONI (first name dot surname at inra dot fr) focuses on the metabolism/degradation of dietary fibers and polyphenols by the human gut microbiota, to better understand the effects of these plant dietary components on health through the action of the microbiota. She isolates microorganisms involved in these metabolic pathways and characterize their function (genes, enzymes, metabolites) and role in health. It should ultimately lead to the discovery of new pre- pro- syn-biotics, or of effective bioactive molecules to be used in preventive or even curative nutritional strategies.Keywords : Human Gut, Microbiota, Metabolism, Degradation, Dietary Fibers, Polyphenols

Dr Marianne DePaepe (first name dot surname at inra dot fr) studies temperate phages that are ubiquitous parasites of bacteria, and greatly impact bacterial populations. In order to improve our understanding of this impact, Marienne studies mainly two aspects of temperate phages: the mortality they induce on gut bacteria in gnotoxenic mice; and their mutation rate, and hence their ability to overcome bacterial resistance.

Keywords : bacteriophages