M2E or MEM

Jerome Hamelin (first name dot surname at inra dot fr) works in Narbonne on the ecological engineering of microbial communities in bioprocesses (anaerobic digestion, wastewater treatment). He is interested in the role of microbial interactions and community assembly processes in shaping the ecosystem functioning. More information available here. [lien hypertexte] https://www6.montpellier.inra.fr/narbonne/Personnel2/Les-chercheurs/Jerome-HAMELIN

Dr Jean-Paul Lallès (jean-paul.lalles@inra.fr) belongs to the Human Nutrition Division of INRA and is located in Rennes, France. His background is agriculture engineering, biochemistry and immunology. His research has been focused on (protein) nutrition and gut (patho)physiology in farm animals, including the pig as a model for human. His present interests include host-microbiota crosstalk in the context of host intestinal defense systems and its nutritional modulation.

Keywords : gut, nutrition, microbiota, defense systems, innate immunity

Philippe Gérard ( first name dot surname at inra dot fr) works in Jouy-en-Josas, France. He investigates the role of the gut microbiota in metabolic diseases (obesity, NAFLD…) mainly using germ- free rodent models, gut microbiota transplants and nutritional modulation of the intestinal ecosystem.

Keywords: obesity, liver diseases, germ-free animal models, gut microbiota transplants, high fat high sugar diets

Sophie Gaudriault (sophie.gaudriault at umontpellier.fr) works in Montpellier, France. She is bacteriologist and investigates interactions between invertebrates (nematodes and insects) and entomopathogenic bacteria, some of which being resident in the animal guts. She is interested in the pathobiome, i.e. the pathogenic bacteria in their biotic environment, and in the modulation of the infectious process by the pathobiome. She is also interest in adaptation and evolution of virulence functions in the view of the holobiont concept, a prioritary theme identified by the INRA M2E flagship.Keywords: bacteria-invertebrate-pathogenic interactions-pathobiome

Muriel Mercier-Bonin (Muriel.Mercier-Bonin@inra.fr) works in Toulouse, France. She investigates the mucus/microbiota crosstalk in the gut by focusing on mucus homeostasis, its disruption through chemical and psychological stresses, and its restoration using nutritional bioremediation strategies (beneficial bacteria).Keywords: mucus/microbiota crosstalk, gut barrier, food xenobiotics, chronic psychological stress, beneficial bacteria

Dr Pascale MOSONI (first name dot surname at inra dot fr) focuses on the metabolism/degradation of dietary fibers and polyphenols by the human gut microbiota, to better understand the effects of these plant dietary components on health through the action of the microbiota. She isolates microorganisms involved in these metabolic pathways and characterize their function (genes, enzymes, metabolites) and role in health. It should ultimately lead to the discovery of new pre- pro- syn-biotics, or of effective bioactive molecules to be used in preventive or even curative nutritional strategies.Keywords : Human Gut, Microbiota, Metabolism, Degradation, Dietary Fibers, Polyphenols