Publikationen

Scientific Papers and Articles

  1. Waxman S, Wang C, Dang Y, Loewen RT, Loewen NA. Tissue-engineered anterior segment eye cultures display intraocular pressure homeostatic response. Preprint. https://paperpile.com/shared/ybyKqo

  2. Strzalkowska A, Strzalkowski P, Yousef A, Grehn F, Hillenkamp J, Loewen NA. Exact matching of trabectome-mediated ab interno trabeculectomy to conventional trabeculectomy with mitomycin C followed for 2 years. Graefes Arch Clin Exp Ophthalmol [Internet]. 2020 Dec 2; Available from: http://dx.doi.org/10.1007/s00417-020-05031-w PMID: 33263824

  3. Esfandiari H, Hassanpour K, Knowlton P, Shazly T, Yaseri M, Loewen NA. Combining Baerveldt Implant with Trabectome Negates Tube Fenestration: A Coarsened-matched Comparison. J Ophthalmic Vis Res. Knowledge E; 2020 Oct 25;15(4):509–516. PMCID: PMC7591847

  4. Strzalkowska A, Strzalkowski P, Al Yousef Y, Hillenkamp J, Grehn F, Loewen N.A. Retrospective evaluation of two-year results with a filtering trabeculotomy in comparison to conventional trabeculectomy by exact matching. F1000Res. F1000 Research Limited; 2020 Oct 15;9(1245):1245.

  5. Strzalkowski P, Strzalkowska A, Göbel W, Loewen NA, Hillenkamp J. Combined vitrectomy, near-confluent panretinal endolaser, bevacizumab and cyclophotocoagulation for neovascular glaucoma — a retrospective interventional case series. F1000Res. F1000 Research Limited; 2020 Oct 14;9(1236):1236.

  6. Brazile BL, Yang B, Waxman S, Lam, Po; Voorhees, Andrew P; Hua, Yi; Loewen, Ralitsa T; Loewen, Nils A; Rizzo 3rd, Joseph F; Jakobs, Tatjana; Sigal, Ian A Lamina Cribrosa Capillaries Straighten as Intraocular Pressure Increases. Invest Ophthalmol Vis Sci. 2020 Oct 1;61(12):2. PMCID: PMC7545063

  7. Al Yousef Y, Strzalkowska A, Hillenkamp J, Rosentreter A, Loewen NA. Comparison of a second-generation trabecular bypass (iStent inject) to ab interno trabeculectomy (Trabectome) by exact matching. Graefes Arch Clin Exp Ophthalmol. 2020 Dec;258(12):2775–2780. PMCID: PMC7677264

  8. Loewen RT, Waxman S, Wang C, Chen, S; Watkins, SC; Watson, AM; Loewen, NA. 3D-Reconstruction of the human conventional outflow system by ribbon scanning confocal microscopy. PLoS One. 2020;15(5):e0232833.

  9. Chen S, Waxman S, Wang C, Atta S, Loewen R, Loewen NA. Dose-dependent effects of netarsudil, a Rho-kinase inhibitor, on the distal outflow tract. Graefes Arch Clin Exp Ophthalmol. 2020;258(6):1211-1216.

  10. Wang, C; Dang, Y; Shah, P; Esfandiari, H; Hong, Y; Loewen, R; Waxman, S; Atta, S; Xia, X; Loewen, N A. Intraocular pressure reduction in a pigmentary glaucoma model by Goniotome Ab interno trabeculectomy. PLoS One. 2020;15(4):e0231360.

  11. Fajardo, R; Sharpsten, L; Loewen, N; Schuman, JS; Goldberg, JL. Steroids After Laser Trabeculoplasty (SALT) Trial: Impact of Short-term Anti-Inflammatory Treatment on SLT Efficacy. Ophthalmology. 2019.

  12. Hong Y, Song SJ, Liu B, Hassanpour K, Zhang C, Loewen N. Efficacy and safety of micropulse laser trabeculoplasty for primary open angle glaucoma. Int J Ophthalmol. 2019 May 18;12(5):784-788. doi: 10.18240/ijo.2019.05.13. eCollection 2019.

  13. Esfandiari H, Taubenslag K, Shah P, Goyal S, Weiner AJ, Severson ML, Weiner A, Grover DS, Bussel II, Loewen NA. Two-year data comparison of ab interno trabeculectomy and trabecular bypass stenting using Exact Matching. J. Cataract Refract. Surg. 2018 [cited 2018 Nov 5]. Available from: https://doi.org/10.1016/j.jcrs.2018.12.011

  14. Esfandiari H, Loewen N. Factors associated with lamina cribrosa displacement after trabeculectomy. Graefes Arch Clin Exp Ophthalmol. 2018 Nov 26; Available from: http://dx.doi.org/10.1007/s00417-018-4199-y PMID: 30478474

  15. Dang Y, Wang C, Shah P, Waxman S, Loewen RT, Loewen NA. RKI-1447, a Rho kinase inhibitor, causes ocular hypotension, actin stress fiber disruption, and increased phagocytosis. Graefes Arch Clin Exp Ophthalmol. 2018 Nov 19; Available from: http://dx.doi.org/10.1007/s00417-018-4175-6 PMID: 30456419

  16. Waxman S, Wang C, Dang Y, Hong Y, Esfandiari H, Shah P, Lathrop KL, Loewen RT, Loewen NA. Structure-Function Changes of the Porcine Distal Outflow Tract in Response to Nitric Oxide. Invest Ophthalmol Vis Sci. The Association for Research in Vision and Ophthalmology; 2018 Oct 1;59(12):4886–4895. PMCID: PMC6181305

  17. Esfandiari H, Shah P, Torkian P, Conner IP, Schuman JS, Hassanpour K, Loewen NA. Five-year clinical outcomes of combined phacoemulsification and trabectome surgery at a single glaucoma center. Graefes Arch Clin Exp Ophthalmol. 2018 Sep 26; Available from: http://dx.doi.org/10.1007/s00417-018-4146-y PMID: 30259089

  18. Hong Y, Wang C, Loewen R, Waxman S, Shah P, Chen S, Loewen NA. Outflow Facility and Extent of Angle Closure in a Porcine Model. Graefes Arch Clin Exp Ophthalmol. 2019 Apr 3. PMID: 30944988

  19. Esfandiari H, Shazly T, Shah P, Hassanpour K, Torkian P, Yaseri M, Loewen NA. Impact of same-session trabectome surgery on Ahmed glaucoma valve outcomes. Graefes Arch Clin Exp Ophthalmol. 2018 Aug;256(8):1509–1515. PMID: 29602960

  20. Dang Y, Wang C, Shah P, Waxman S, Loewen RT, Hong Y, Esfandiari H, Loewen NA. Outflow enhancement by three different ab interno trabeculectomy procedures in a porcine anterior segment model. Graefes Arch Clin Exp Ophthalmol. 2018 Jul;256(7):1305–1312. PMID: 29721662

  21. Esfandiari H, Loewen NA, Hassanpour K, Fatourechi A, Yazdani S, Wang C, Yaseri M, Pakravan M. Fuchs heterochromic iridocyclitis-associated glaucoma: a retrospective comparison of primary Ahmed glaucoma valve implantation and trabeculectomy with mitomycin C. F1000Res. 2018 Jun 22;7:876. PMCID: PMC6198260.2

  22. Dang Y-L, Wang X, Dai W-W, Huang P, Loewen NA, Zhang C, China Trabectome Study Group, International Trabectome Study Group. Two-year outcomes of ab interno trabeculectomy with the Trabectome for Chinese primary open angle glaucoma: a retrospective multicenter study. Int J Ophthalmol. 2018 Jun 18;11(6):945–950. PMCID: PMC6010386

  23. Stetten G, Klatzky RL, H-Y. LH, Satpute S, Loewen N, Amesur N. In Situ Augmentation of Force and Torque Perception using Patient-Based Forces. Int J Comput Assist Radiol Surg. 2018 Jun;13(Suppl. 1):S237–238.

  24. Esfandiari H, Shazly TA, Waxman SA, Kola S, Kaplowitz KB, Brown EN, Loewen NA. Similar Performance of Trabectome and Ahmed Glaucoma Devices in a Propensity Score-matched Comparison. J Glaucoma. 2018 Jun;27(6):490–495. PMID: 29613976

  25. Waxman S, Loewen RT, Dang Y, Watkins SC, Watson AM, Loewen NA. High-Resolution, Three-Dimensional Reconstruction of the Outflow Tract Demonstrates Segmental Differences in Cleared Eyes. Invest Ophthalmol Vis Sci. The Association for Research in Vision and Ophthalmology; 2018 May 1;59(6):2371–2380. PMCID: PMC5939687

  26. Dang Y, Waxman S, Wang C, Loewen RT, Sun M, Loewen NA. A porcine ex vivo model of pigmentary glaucoma. Sci Rep. 2018 Apr 3;8(1):5468. PMCID: PMC5882895

  27. Wang C, Dang Y, Loewen RT, Waxman S, Shah P, Xia X, Loewen NA. Impact of pigment dispersion on trabecular meshwork cells. Graefes Arch Clin Exp Ophthalmol. 2019 Mar 28.

  28. Esfandiari H, Pakravan M, Amouhashemi N, Yaseri M, Torkian P, Jadidi K, Loewen NA. Factors Associated with Lamina Cribrosa Displacement After Trabeculectomy Measured by Optical Coherence Tomography in Advanced Primary Open Angle Glaucoma. Graefes Arch Clin Exp Ophthalmol. 2018 Feb 24 [cited 2018 Feb 26]; Available from: http://dx.doi.org/10.1007/s00417-018-4092-8 PMID: 30073624

  29. Dang Y, Waxman S, Wang C, Shah P, Loewen RT, Loewen NA. Intraocular pressure elevation precedes a phagocytosis decline in a model of pigmentary glaucoma. F1000Res. 2018 Feb 12;7:174. PMCID: PMC5915754

  30. Esfandiari H, Hassanpour K, Yaseri M, Loewen NA. Extended pharmacological miosis is superfluous after glaucoma angle surgery: A retrospective study. F1000Res. 2018 Feb 12;7:178. PMCID: PMC5897784

  31. Dang Y, Wang C, Shah P, Waxman S, Loewen RT, Esfandiari H, Loewen NA. Goniotome ab interno trabeculectomy reduces IOP in an ex vivo model of pigmentary glaucoma. Researchgate preprint. 2018 Jan 26;

  32. Kostanyan T, Shazly T, Kaplowitz KB, Wang SZ, Kola S, Brown EN, Loewen NA. Longer-term Baerveldt to Trabectome glaucoma surgery comparison using propensity score matching. Graefes Arch Clin Exp Ophthalmol. 2017 Dec;255(12):2423–2428. PMID: 28944413

  33. Esfandiari H, Hassanpour K, Knowlton P, Shazly TA, Loewen NA. Trabectome Surgery Combined with Baerveldt Glaucoma Implantation Negates Tube Fenestration. Preprint 1013140/RG221501565445. 2017 Nov 17 [cited 2017 Nov 16].

  34. Esfandiari H, Pakravan M, Loewen NA, Yaseri M. Predictive value of early postoperative IOP and bleb morphology in Mitomycin-C augmented trabeculectomy. F1000Res. 2017 Oct 27;6:1898. PMCID: PMC5747341.2

  35. Dang, Y; Waxman, S; Wang, C; Jensen, A; Loewen R; Bilonick, R; Loewen, NA. Freeze-thaw decellularization of the trabecular meshwork in an ex vivo eye perfusion model. PeerJ. 2017 Aug 14;5:e3629. doi: 10.7717/peerj.3629.

  36. Wang C, Dang Y, Waxman S, Xia X, Weinreb RN, Loewen NA. Angle stability and outflow in dual blade ab interno trabeculectomy with active versus passive chamber management. PLoS One. 2017 May 9;12(5):e0177238. PMID: 28486513

  37. Dang Y, Waxman S, Wang C, Parikh HA, Bussel II, Loewen RT, Xia X, Lathrop KL, Bilonick RA, Loewen NA. Rapid learning curve assessment in an ex vivo training system for microincisional glaucoma surgery. Sci Rep. 2017 May 9;7(1):1605. PMID: 28487512

  38. Roy P, Loewen RT, Dang Y, Parikh HA, Bussel I, Loewen NA. Stratification of phaco-trabectome surgery results using a glaucoma severity index in a retrospective analysis. BMC Ophthalmol. 2017;17:30.

  39. Fallano, K; Bussel, II; Kagemann, L; Lathrop, KL; Loewen, NA. Training strategies and review of ab interno trabeculectomy with the trabectome. f1000research.com/articles/6-67/v1.

  40. Dang, Y; Loewen NA. Commentary: The CyPass, a Novel Supraciliary Implant for Open-Angle Glaucoma. Yan ke xue bao (Eye Science). September 2016.

  41. Parikh HA, Loewen RT, Roy P, Schuman JS, Lathrop KL, Loewen NA. Differential Canalograms Detect Outflow Changes from Trabecular Micro-Bypass Stents and Ab Interno Trabeculectomy. Sci. Rep. Nature Publishing Group; 2016;6:34705.

  42. Loewen N, Francis BA, Hong B, Dustin L, Kaplowitz K, Kinast R, Bacharach J, Radhakrishnan S, Iwach A, Rudavska L, Ichhpujani P, Katz LJ. Repeatability of selective laser trabeculoplasty for open-angle glaucoma. BMC Ophthalmol. 2016 Jul 28;16:128. doi: 10.1186/s12886-016-0299-9.

  43. Dang Y, Kaplowitz K, Parikh HA, Roy P, Loewen RT, Francis BA, Loewen NA. Steroid-induced glaucoma treated with trabecular ablation in a matched comparison to primary open angle glaucoma. Clin Experiment Ophthalmol. June 2016. doi:10.1111/ceo.12796.

  44. Dang Y, Roy P, Bussel II, Loewen RT, Parikh HA, Loewen NA. Combined analysis of trabectome and phaco-trabectome outcomes by glaucoma severity. F1000Res. 2016;5:762.

  45. Loewen RT, Brown EN, Scott G, Parikh H, Schuman JS, Loewen NA. Quantification of Focal Outflow Enhancement Using Differential Canalograms. Invest Ophthalmol Vis Sci. 2016;57(6):2831-2838.

  46. Neiweem AE, Bussel II, Schuman JS, Brown EN, Loewen NA. Glaucoma Surgery Calculator: Limited Additive Effect of Phacoemulsification on Intraocular Pressure in Ab Interno Trabeculectomy. PLoS One. 2016;11(4):e0153585.

  47. Loewen RT, Roy P, Parikh H, Dang Y, Schuman JS, Loewen N.A. Impact of a Glaucoma Severity Index on Results of Trabectome Surgery: Larger Pressure Reduction in More Severe Glaucoma. PLoS One. 2016;11(3):e0151926.

  48. Loewen RT ,Brown EN, Roy P, Schuman JS, Sigal IA, Loewen N.A. Regionally Discrete Aqueous Humor Outflow Quantification Using Fluorescein Canalograms. PLoS One. 2016;11(3):e0151754.

  49. Kaplowitz, K., Wang, S., Bilonick, R., Oatts, J.T., Grippo, T., Loewen, N.A. Randomized Controlled Comparison of Titanium-Sapphire versus Standard Q-switched Nd:YAG Laser Trabeculoplasty. J Glaucoma. 2016 Jul;25(7):e663-7.

  50. Polat JK, Loewen NA. Combined phacoemulsification and trabectome for treatment of glaucoma. Surv Ophthalmol. May 2016. doi:10.1016/j.survophthal.2016.03.012.

  51. Kaplowitz K, Bussel I.I., Honkanen R., Schuman J.S., Loewen N.A. Review and Meta-Analysis of Ab-Interno Trabeculectomy Outcomes. Br J Ophthalmol. 2016 May;100(5):594-600. doi: 10.1136/bjophthalmol-2015-307131. Review. PMID: 26733487

  52. Dang Y, Loewen R, Parikh HA, Roy P, Loewen N.A. Gene Transfer to the Outflow Tract. Exp Eye Res. 2016 Apr 27. pii: S0014-4835(16)30096-3. doi: 10.1016/j.exer.2016.04.023.

  53. Loewen RT, Roy P, Park DB, Jensen A, Scott G, Cohen-Karni D, Fautsch MP, Schuman JS, Loewen N.A. A Porcine Anterior Segment Perfusion and Transduction Model with Direct Visualization of the Trabecular Meshwork. Invest Ophthalmol Vis Sci. 2016 Mar 1;57(3):1338-44. doi: 10.1167/iovs.15-18125.

  54. Zhang X, Francis BA, Dastiridou A, Chopra V, Tan O, Varma R, Greenfield DS, Schuman JS, Huang D; Advanced Imaging for Glaucoma Study Group. Longitudinal and Cross-Sectional Analyses of Age Effects on Retinal Nerve Fiber Layer and Ganglion Cell Complex Thickness by Fourier-Domain OCT. Transl Vis Sci Technol. 2016 Mar 4;5(2):1. eCollection 2016 Mar. PubMed PMID: 26966637; PubMed Central PMCID: PMC4782827.

  55. Zhang X, Loewen N, Tan O, Greenfield DS, Schuman JS, Varma R, Huang D; Advanced Imaging for Glaucoma Study Group. Predicting Development of Glaucomatous Visual Field Conversion Using Baseline Fourier-Domain Optical Coherence Tomography. Am J Ophthalmol. 2016 Mar;163:29-37. doi: 10.1016/j.ajo.2015.11.029.

  56. Akil H, Chopra V, Huang A, Loewen N, Noguchi J, Francis BA. Clinical Results of Ab Interno Trabeculotomy Using the Trabectome in Patients with Pigmentary Glaucoma compared to Primary Open Angle Glaucoma. Clin Experiment Ophthalmol. 2016 Mar 6. doi: 10.1111/ceo.12737.

  57. Parikh HA, Bussel II, Schuman JS, Brown EN, Loewen NA. Coarsened Exact Matching of Phaco-Trabectome to Trabectome in Phakic Patients: Lack of Additional Pressure Reduction from Phacoemulsification. PLoS One. 2016 Feb 19;11(2):e0149384.

  58. Richter GM, Zhang X, Tan O, Francis BA, Chopra V, Greenfield DS, Varma R, Schuman JS, Huang D; Advanced Imaging for Glaucoma Study Group. Regression Analysis of Optical Coherence Tomography Disc Variables for Glaucoma Diagnosis. J Glaucoma. 2016 Feb 19. [Epub ahead of print] PubMed PMID: 26900833.

  59. Oatts JT, Wang X, Loewen NA. Effect of alpha-2-agonist premedication on intraocular pressure after selective laser trabeculoplasty. Indian J Ophthalmol. 2015 Dec;63(12):891-4.

  60. Kaplowitz K, Blizzard S, Blizzard DJ, Nwogu E, Hamill CE, Weinreb RN, Mohsenin V, Loewen NA. Time Spent in Lateral Sleep Position and Asymmetry in Glaucoma. Invest Ophthalmol Vis Sci. 2015;56(6):3869-3874.

  61. Loewen, N.A., Zhang, X, Tan O., Greenfield D.S., Schuman J.S., Varma R., Huang D. Combining measurements from three anatomical areas for glaucoma diagnosis using Fourier-domain optical coherence tomography. Br J Ophthalmol. 2015. doi:10.1136/bjophthalmol-2014-305907.

  62. Iverson SM, Feuer WJ, Shi W, Greenfield DS; Advanced Imaging for Glaucoma Study Group. Frequency of abnormal retinal nerve fibre layer and ganglion cell layer SDOCT scans in healthy eyes and glaucoma suspects in a prospective longitudinal study. Br J Ophthalmol. 2014 Jul;98(7):920-5. PubMed PMID: 24627246.

  63. Le PV, Zhang X, Francis BA, Varma R, Greenfield DS, Schuman JS, Loewen N, Huang D, Advanced Imaging for Glaucoma Study Group. Advanced Imaging for Glaucoma Study: Design, Baseline Characteristics, and Inter-Site Comparison. Am. J. Ophthalmol. 2014. doi:10.1016/j.ajo.2014.11.010.

  64. Bussel II, Kaplowitz K, Schuman JS, Loewen NA, Trabectome Study Group. Outcomes of ab interno trabeculectomy with the trabectome by degree of angle opening. Br. J. Ophthalmol. 2014. doi:10.1136/bjophthalmol-2014-305577.

  65. Bussel II, Kaplowitz K, Schuman JS, Loewen NA, Trabectome Study Group. Outcomes of ab interno trabeculectomy with the trabectome after failed trabeculectomy. Br. J. Ophthalmol. 2014. doi:10.1136/bjophthalmol-2013-304717.

  66. Minckler D, Mosaed S, Francis B, Loewen N, Weinreb RN. Clinical results of ab interno trabeculotomy using the Trabectome for open-angle glaucoma: the Mayo clinic series in Rochester, Minnesota. Am. J. Ophthalmol. 2014;157(6):1325-1326.

  67. Kaplowitz K, Schuman JS, Loewen NA. Techniques and outcomes of minimally invasive trabecular ablation and bypass surgery. Br. J. Ophthalmol. 2014;98(5):579-585.

  68. Zhang Z, Dhaliwal AS, Tseng H, Kim JD, Schuman JS, Weinreb RN, Loewen NA. Outflow tract ablation using a conditionally cytotoxic feline immunodeficiency viral vector. Invest. Ophthalmol. Vis. Sci. 2014;55(2):935-940.

  69. Kaplowitz K, Abazari A, Honkanen R, Loewen N. iStent surgery as an option for mild to moderate glaucoma. Expert Rev. Ophthalmol. 2014;9(1):11-16.

  70. Kaplowitz K., Schuman J.S., Loewen N.A. Techniques and Outcomes of Minimally-Invasive Trabecular Ablation and Bypass Surgery. Br J Ophthal. 97.10 (2013): 1228-1229.

  71. Loewen N.A., Schuman JS. There has to be a better way: evolution of internal filtration glaucoma surgeries. Br J Ophthalmol. 2013 Oct;97(10):1228-9.

  72. Oatts J.T., Zhang Z., Tseng H.P., Shields M.B., Sinard J.H., Loewen N.A. In Vitro and In Vivo Comparison of Two Suprachoroidal Shunts. Invest Ophthalmol Vis Sci 54.8 (2013): 5416-5423.

  73. Marcus I., Salchow D.J., Sophie L. Leung, Elaine J. Zhou, Tsai J.C., Loewen N.A. Academic Associate Program Impact on Clinical Study Enrollment in an Academic Ophthalmology Practice. J Academic Ophthalmol. 2013;6(1):69-75

  74. Sigler EJ, Mascarenhas KG, Tsai JC, Loewen NA. Clinicopathologic Correlation of Disc and Peripapillary Region Using SD-OCT. Optom Vis Sci. 2013. Jan;90(1):84-93.

  75. Ni N, Tsai JC, Shields MB, Loewen NA. Elevation of intraocular pressure in glaucoma patients after automated visual field testing. J Glaucoma. 2012 Dec;21(9):590-5.

  76. Saenz DT, Barraza R, Loewen N, Teo W, Poeschla EM. Feline immunodeficiency virus-based lentiviral vectors. Cold Spring Harb Protoc. 2012 Jan 1;2012(1):71-6.

  77. Saenz DT, Barraza R, Loewen N, Teo W, Poeschla EM. Titration of feline immunodeficiency virus-based lentiviral vector preparations. Cold Spring Harb Protoc. 2012 Jan 1;2012(1):126-8.

  78. Saenz DT, Barraza R, Loewen N, Teo W, Poeschla EM. Production and harvest of feline immunodeficiency virus-based lentiviral vector from cells grown in T75 tissue-culture flasks. Cold Spring Harb Protoc. 2012 Jan 1;2012(1):124-5.

  79. Saenz DT, Barraza R, Loewen N, Teo W, Poeschla EM. Production, harvest, and concentration of feline immunodeficiency virus-based lentiviral vector from cells grown in CF10 or CF2 devices. Cold Spring Harb Protoc. 2012 Jan 1;2012(1):118-23.

  80. George M., Tsai J.C., Loewen, N.A. Bilateral Irreversible Severe Vision Loss from Cosmetic Iris Implants. Am J Ophthalmol. 2011 May;151(5):872-875.

  81. Guedes G., Tsai J.C., Loewen N. Glaucoma and Aging. Curr Aging Sci. 2011 Jan 14.

  82. Loewen N. Vision Loss after Trabeculectomy in Advanced Glaucoma. Glaucoma Today. Nov 2009.

  83. Loewen N., Liu J.H.K., Weinreb R.N. Increased 24-Hour Variation of Human Intraocular Pressure with Short Axial Length. Invest Ophthalmol Vis Sci. 2009 Sep 9.

  84. Loewen N., Chen J., Dudley V.J., Sarthy V.P., Mathura J.R., Jr. Genomic response of hypoxic Müller cells involves the very low density lipoprotein receptor as part of an angiogenic network. Exp Eye Res. 2009 May;88(5):928-37.

  85. Barraza R.A., Rasmussen C.A., Loewen N., Cameron D.J., Gabelt B.T., Teo W., Kaufman P.L., Poeschla E.M. Prolonged transgene expression with lentiviral vectors in the aqueous humor outflow pathway of nonhuman primates. Hum Gene Ther. 2009 Mar;20(3):191-200.

  86. Ezzat M.K., Howell K.G., Bahler C.K., Beito T.G., Loewen N., Poeschla E.M., Fautsch M.P. Characterization of Monoclonal Antibodies against the Glaucoma-Associated Protein Myocilin. Exp Eye Res. 2008 Oct;87(4):376-84.

  87. Khare P., Loewen N., Teo W., Barraza R., Saenz D.T., Johnson D.H., Poeschla E.M. Durable, Safe, Multi-gene Lentiviral Vector Expression for Over Two Years in Feline Trabecular Meshwork. Mol Ther. 2008 Jan;16(1):97-106.

  88. Fautsch MP, Bahler CK, Vrabel AM, Howell KG, Loewen N., Teo WL, Poeschla EM, Johnson DH. Perfusion of HIS-tagged eukaryotic myocilin increases outflow resistance in human anterior segments in the presence of aqueous humor. Invest Ophthalmol Vis Sci. 2006 Jan;47(1):213-21.

  89. Loewen N., Poeschla E.M. Lentiviral Vectors. Adv Biochem Eng Biotechnol. 2005;99:169-91.

  90. Loewen N., Fautsch M.P., Teo W., Bahler C.K., Johnson D.H., Poeschla E.M. Long-term, targeted genetic modification of the aqueous humor outflow tract coupled with non-invasive imaging of gene expression in vivo. Invest Ophthalmol Vis Sci. 2004 Sep;45(9):3091-98.

  91. Loewen N., Leske D.A., Cameron J.D., Chen Y., Teo W., Fautsch M.P, Poeschla E.M., Holmes J.M. Long-term retinal transgene expression with FIV versus adenoviral vectors. Mol Vis. 2004 Apr 13;10:272-80.

  92. Saenz D.T., Loewen N., Peretz M., Whitwam T., Howell K.G., Holmes J.M., Good M., Poeschla E.M. Unintegrated lentiviral DNA persistence and accessibility to expression in nondividing cells: analysis with class I integrase mutants. J. Virol. 2004 Mar;78(6):2906-20.

  93. Loewen N., Leske D.A., Chen Y., Teo W., Saenz D.T., Peretz M., Holmes J.M., Poeschla E.M. Comparison of wild type and class I integrase mutant-FIV vectors in retina demonstrates sustained expression of integrated transgenes in retinal pigment epithelium. J Gene Med. 2003 Dec;5(12):1009-17.

  94. Loewen N., Bahler C., Teo W., Whitwam T., Peretz M., Xu R., Fautsch M., Johnson D.J., Poeschla E.M. Preservation of aqueous outflow facility after second-generation FIV vector-mediated expression of marker genes in anterior segments of human eyes. Invest Ophthalmol Vis Sci. 2002 Dec;43(12):3686-90.

  95. Loewen N., Fautsch M.P., Peretz M., Bahler C.K., Cameron J.D., Johnson D.H., Poeschla E.M. Genetic modification of human trabecular meshwork with lentiviral vectors. Hum Gene Ther. 2001 Nov 20; 12(17): 2109-19.

  96. Barry J.C., Loewen N. The use of cycloplegic agents. Results of a 1999 survey of German-speaking centers for pediatric ophthalmology and strabology. Klin Monatsbl Augenheilkd 2001 Jan; 218(1): 26-30.

  97. Loewen N., Barry J.C. The use of cycloplegic agents. Results of a 1999 survey of German-speaking centers for pediatric ophthalmology and strabology. Strabismus 2000 Jun; 8(2):91-9.

Other Peer-Reviewed Publications

  1. Fallano, K., Loewen, N.A. New insights into plasma-mediated ab interno trabeculectomy with the trabectome: Analyses of our outcomes data with advanced statistical methods indicate an expanded use range. Ophthalmology Management. December 2016.

  2. Loewen R.T., Loewen, N.A. Trabectome and glaucoma index: larger pressure reduction in more severe glaucoma. Ocular Surgical News, July 2016.

  3. Parikh H. Loewen. N.A. New study shows that phacoemulsification does not contribute to IOP reduction in Trabectome surgery. Ocular Surgical News, April 2016

  4. Loewen, N.A., Dang, Y. Editors Selection IGR 17-3 Basic Science: In vitro Trabecular Meshwork Model. International Glaucoma Review March 2016.

  5. Bussel I., Loewen N.A.. Expanding Indications of Minimally Invasive Glaucoma Surgery with the Trabectome. Ocular Surgical News February 2016.

  6. Parikh H., Bussel I., Loewen. N.A. Ab interno trabeculectomy demonstrates positive outcomes, even in patients with narrow angles. Ophthalmology Times Europe. September 2015.

  7. Hardik A. Parikh, Pritha Roy, Amar Dhaliwal, Kevin B. Kaplowitz, Nils A. Loewen. Trabectome Patient Selection, Preparation, Technique, Management, and Outcomes. US Ophthalmic Review. October 2015.

  8. Kaplowitz K., Bussel I., Schuman J.S., Loewen N.A. Expanding Indications of Ab-Interno Trabeculectomy. Ophthalmology Times Europe. December 2014.

  9. Polat J., Loewen N.A. Trabectome: Ab Interno Trabeculectomy. EyeWiki September 2014.

  10. Brown E., Loewen N.A. Treatment Pathways in Glaucoma and Cataract Care. Ocular Surgery News, March 2014.

  11. Lagouros E., Loewen N.A. The Right Microscope for Demanding Surgery. Ocular Surgery News, February 2014.

  12. Loewen N.A. Large referral center explores efficacy of Trabectome-mediated ab interno trabeculectomy. Ocular Surgery News, January 2014.

  13. K Kaplowitz, A Abazari, R Honkanen and N Loewen. iStent Surgery as an Option for Mild to Moderate Glaucoma. Expert Rev Ophthalmol. 2013 Dec 18.

  14. Kim J, Loewen N.A. International Glaucoma Review 15-1, 2013 “Optimizing gene transfer to conventional outflow cells in living mouse eyes.”

  15. Loewen N.A. Opinion Piece: We Must Do Better, Acquire Excellent MIGS Skills. International Glaucoma Review. March 2013

  16. Loewen N.A. The Suprachoroidal Space in Glaucoma Surgery. Refractive Eyecare. July 2012.

  17. Kaplowitz K., Loewen N.A. Trabectome Surgery: A Minimally-Invasive Glaucoma Procedure. Publication by the Glaucoma Research Foundation. May 17, 2012

  18. Loewen N.A. Combined Glaucoma and Cataract Procedures. In Print.

  19. Kaplowitz K.B., Loewen N.A. Surgical Management of the Loose Lens. US Ophthalmic Review, 2013;6(2):105–8.

  20. Kaplowitz K.B., Loewen N.A. High IOP in Traumatic Hyphema. Glaucoma Today. May 2012.

  21. Thomas, S., Loewen N.A. The Literature Column. Glaucoma Today. Apr 2011.

  22. Loewen N.A. Xalatan going generic. Glaucoma Today. Apr 2011.

  23. Loewen N.A. Ophthalmology Management. June 2011. “Advantages of FORUM Implementation”

  24. Ahrlich K.G., Loewen N.A. Glaucoma Diagnostic Technologies. Cataract & Refractive Surgery Today Europe, May 2011.

  25. Loewen N.A. Ocular Surgery News. September 2010. "Glaucoma Medications: Not a First Choice".

  26. Loewen N.A. International Glaucoma Review 12-3, 2010 "Gene delivery of erythropoietin protects retinal ganglion cells in DBA/2J glaucomatous mice. Sullivan T.A, Geisert E.E, Rex T.S.Molecular Therapy 2010; 18: S171"

  27. Loewen N.A. International Glaucoma Review 12-2, 2010 "Adenoviral Gene Transfer of Active Human Transforming Growth Factor-Beta2 Elevates Intraocular Pressure and Reduces Outflow Facility in Rodent Eyes."

  28. Loewen N.A. International Glaucoma Review 12-1, 2010 "Self-complementary AAV virus (scAAV) safe and long-term gene transfer in the trabecular meshwork of living rats and monkeys. Buie LK, Rasmussen CA, Porterfield EC, Ramgolam VS, Choi VW, Markovic-Plese S, Samulski RJ, Kaufman PL, Borrás T. Invest Ophthalmol Vis Sci. 2010; 51: 236-248."

  29. Loewen N.A. International Glaucoma Review 11-3, 2010 "Long-term outcomes of needle revision of trabeculectomy blebs with mitomycin C and 5-fluorouracil: a comparative safety and efficacy report. Anand N, Khan A. J Glaucoma 2009; 18: 513-520"

  30. Loewen N. Ophthalmic Surgical Procedures. J Glaucoma. 2009 Oct 22.

  31. Loewen N. Tsai J.C. Managing a Failing Bleb. Glaucoma Today. October 2009.

  32. Loewen N. Poor office visit follow-up compliance could affect glaucoma surgical success. Ocular Surgery News. July 2010.

  33. Loewen N., Schanzlin D.J., Vizzeri G., Weinreb R.N. Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK) in a Patient with Trabeculectomy. Glaucoma Today. 2008 Oct:15-18.

  34. Loewen N., Weinreb R.N. Book review: Curbside Consultation in Glaucoma. SLACK Incorporated, 2008 J. Glaucoma. November 2008.

Book Chapters

  1. Loewen RT, Waxman S, Kollech H, Geest JV, Loewen NA. Imaging Aqueous Humor Outflow. Imaging Aqueous Humor Outflow. Preprint July 2019.

  2. Esfandiari, H; Chen, S; Loewen, RT; Waxman, S; Loewen, NA. Ab-interno trabecular meshwork incision, ablation, and disruption. Book Chapter. Preprint July 2019.

  3. World Glaucoma Association Microincisional Glaucoma Surgery Consensus 2019 - Trabectome and Goniotome. January 2019. Preprint.

  4. Kaplowitz K., Bussel I., Loewen N.A. Chapter 10.28 Microincisional Glaucoma Surgeries in Ophthalmology: Expert Consult: Online and Print (eds. Yanoff, M. & Duker, J. S.) 1133–1146 (Elsevier - Health Sciences Division, 2017).

  5. Kaplowitz K., Bussel I., Loewen N.A. Minimally Invasive Glaucoma Surgery: the Science and the Practice. Chapter 7: Trabeculectomy by Internal Approach: Trabectome. Eds Francis B. & Sarkisian S. Thieme, September 2016.

  6. Kaplowitz, K., Loewen, N. A. Trabectome-Mediated Ab Interno Trabeculectomy for Secondary Glaucoma or as a Secondary Procedure (eds. Aref, A. A. & Varma, R.) 51–73 (Springer, 2014).

  7. Kaplowitz K., Bussel I., Loewen N.A. Minimally Invasive and Nonpenetrating Glaucoma Surgery in Ophthalmology: Expert Consult: Online and Print (eds. Yanoff, M. & Duker, J. S.) 1133–1146 (Elsevier - Health Sciences Division, 2013).

  8. Kaplowitz K., Loewen N.A. Minimally Invasive Glaucoma Surgery: Trabeculectomy Ab Interno. Surgical Innovations in Glaucoma. (eds. Samples, John R. & Ahmed, Iqbal Ike K.) Springer New York, 2014. 175-186.

  9. Loewen N.A., Tanna A.P. Role of Intraocular Pressure in the Diagnosis and Treatment of Glaucoma. In: Schacknow PN, Samples JR The Glaucoma Book: A Practical, Evidence-Based Approach to Patient Care. 2013. 2nd Edition. Springer. 35-50.

  10. Loewen N.A., Tanna A.P. Role of Intraocular Pressure in the Diagnosis and Treatment of Glaucoma. In: Schacknow PN, Samples JR The Glaucoma Book: A Practical, Evidence-Based Approach to Patient Care. First. Springer; 2010:1016.

  11. Saenz D.T., Barraza R., Loewen N., Teo W., Poeschla E., 2005, Production and Use of Feline Immunodeficiency Virus (FIV)-Based Lentiviral Vectors, In: Rossi, J., Friedman, T. (Eds.) Gene Transfer: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. 57-73

  12. Loewen N., Barraza R., Whitwam T., Saenz, D.T., Kemler I., Poeschla E.M. FIV Vectors. In M. Federico: Lentiviral gene engineering protocols. Humana Press, USA, 2003: 251-273.