Essential Knowledge 4.A.3

Interactions between external stimuli and regulated gene expression result in specialization of cells, tissues and organs.

Differentiation in development is due to external and internal cues that trigger gene regulation by proteins that bind to DNA.

Structural and functional divergence of cells in development is due to expression of genes specific to a particular tissue or organ type.

Environmental stimuli can affect gene expression in a mature cell.

Students should be able to:

LO 4.7 refine representations to illustrate how interactions between external stimuli and gene expression result in specialization of cells, tissues and organs.