論文原著

Kosaka H, Fujioka T, Jung MSymptoms inindividuals with adult-onset ADHD are masked during childhood.

Eur Arch Psychiatry Clin Neurosci, 2018.04

Morita T, Saito DN, Ban M, Shimada K, Okamoto Y, Kosaka H, Okazawa H, Asada M, Naito E.

Self-face recognition begins to share active brain region in right inferior parietal lobule with proprioceptive illusion during adolescence.

Cereb. Cortex, in press.

Kasagi M, Huang Z, Narita K, Shitara H, Motegi T, Suzuki Y, Fujihara K, Tanabe S, Kosaka H, Ujita K, Fukuda M, and Northoff G.

Association between scale-free brain dynamics and behavioral performance – Functional MRI study in resting state and emotional face recognition task.

Behav. Neurol., in press.

市川宏伸、齊藤万比古、齊藤卓弥、仮屋暢聡、小平雅基、太田晴久、岸田郁子、三上克央、太田豊作、姜 昌勲、小坂浩隆、堀内史枝、藤原正和、岩波 明

成人用ADHD評価尺度 ADHD-RS IV with adult prompts日本語版の信頼性および妥当性の検討

精神医学, in press.

＝＝＝2017 ＝＝＝

小坂浩隆

自閉スペクトラム症の臨床研究の動向

北陸神経精神医学雑誌, 37: 14-27, 2017.12

Naito E, Morita T, Saito DN, Ban M, Shimada K, Okamoto Y, Kosaka H, Okazawa H, Asada M.

Development of right-hemispheric dominance of inferior parietal lobule in proprioceptive illusion task.

Cereb. Cortex, 27(11): 5385-5397, 2017.11

藤岡徹

自閉スペクトラム症の認知機能―ASD特性を説明する理論にそって―

LD研究, 26(4): 474-483, 2017.11

藤岡徹

教員研修プログラムと児童生徒支援プログラムの開発について

子どものこころと脳の発達, 8: 36-46, 2017.10

Jung M, Tu Y, Lang CA, Ortiz A, Park J, Jorgenson K, Kong XJ, Kong J.

Decreased structural connectivity and resting-state brain activity in the lateral occipital cortex is associated with social communication deficits in boys with autism spectrum disorder

Neuroimage, S1053-8119(17): 30779-6, 2017.9

Fukai M, Hirosawa T, Kikuchi M, Ouchi Y, Takahashi T, Yoshimura Y, Miyagishi Y, Kosaka H, Yokokura M, Yoshikawa E, Bunai T, Minabe Y.

Oxytocin effects on emotional response to others' faces via serotonin system in autism: a pilot study.

Psychiatry Res., 267: 45-50, 2017.9

小坂浩隆

「2016年度のASDへのオキシトシン研究から」

発達障害白書 2018年版、54-55, 2017.09.

Shimada K, Fujisawa TX, Takiguchi S, Naruse H, Kosaka H, Okazawa H, Tomoda A.

Ethnic differences in COMT genetic effects on striatal grey matter alterations associated with childhood ADHD: a voxel-based morphometry study in a Japanese sample.

World J. Biol. Psychiatry,18(4),322-3282017.6

Mizuno Y, Jung, M, Fujisawa TX, Takiguchi S, Shimada K, Saito DN, Kosaka H, Tomoda A.

Catechol-O-methyltransferase polymorphism alters the cortico-cerebellar executive function network in children with attention-deficit/hyperactivity disorder.

Scientific Reports, 7:4850, 2017.07.

小坂浩隆

「オキシトシン治療のこれから」

小児科診療、80(7): 843-849、2017.07.

Okamoto Y, Kosaka H, Kitada R, Seki A, Tanabe HC, Hayashi MJ, Kochiyama T, Saito DN, Yanaka HT, Munesue T, Ishitobi M, Omori M, Wada Y, Okazawa H, Koeda T, Sadato N.

Age-dependent atypicalities in body- and face-sensitive activation of the EBA and FFA in individuals with ASD.

Neurosci Res. 119:38-52, 2017.06.

Hirosawa T, Kikuchi M,, Ouchi Y, Takahashi T, Yoshimura Y, Kosaka H, Furutani N, Hiraishi H, Fukai M, Yokokura M, Yoshikawa E, Bunai T, Minabe Y.

A pilot study of serotonergic modulation after long-term administration of oxytocin in autism spectrum disorder.

Autism Research, 10(5):821-828, 2017.05.

小坂浩隆、藤岡徹

「発達障害の子どもから大人への連続性について」

最新精神医学、特集「成人期発達障害の最新課題」、22(3): 197-208、2017.05.

Nishizato M, Fujisawa TX, Kosaka H, Tomoda A.

Developmental changes in social attention and oxytocin secretion in infants and children.

Scientific Reports, 7(1):2540, 2017.05.

Morita T, Saito DN, Ban M, Shimada K, Okamoto Y, Kosaka H, Okazawa H, Asada M, Naito E.

Self-face recognition shares brain regions active during proprioceptive illusion in the right inferior fronto-parietal superior longitudinal fasciculus III network.

Neuroscience, 348: 288–301, 2017.04.

Naruse H, Fujisawa TX, Yatsuga C, Kubota M, Matsuo H, Takiguchi S, Shimada S, Imai Y, Hiratani M, Kosaka H, Tomoda A.

Increased Anterior Pelvic Angle Characterizes the Gait of Children with Attention deficit/hyperactivity disorder (ADHD).

PLOS ONE, 12(1):e0170096, 2017.01.

＝＝＝2016 ＝＝＝

高岡健、岡田俊、小坂浩隆、野間俊一、森岡由起子、吉川 徹

委員会報告「児童青年精神医学用語集2016年版の刊行について」

児童青年精神医学とその近接領域 57(4): 628-664, 2016.

Komeda H, Osanai H, Yanaoka K, Okamoto Y, Fujioka T, Arai S, Inohara K, Koyasu M, Kusumi T, Takiguchi S, Kawatani M, Kumazaki H, Hiratani M, Tomoda A, Kosaka H.

OA! ⇒ Decision making processes based on social conventional rules in early adolescents with and without autism spectrum disorders.

Scientific Reports. 6: 37875, 2016. プレスリリース

小坂浩隆

「統合失調症と自閉スペクトラム症」

精神科、29 ：381-389、2016.

Kosaka H, Okamoto Y, Munesue T, Yamasue H, Inohara K, Fujioka T, Anme T, Orisaka M, Ishitobi M, Jung M, Fujisawa TX, Tanaka S, Arai S, Asano M, Saito DN, Sadato N, Tomoda A, Omori M, Sato M, Okazawa H, Higashida H, Wada Y.

OA! ⇒ Oxytocin efficacy is modulated by dosage and oxytocin receptor genotype in young adults with high-functioning autism: A 24-week randomized clinical trial.

Translational Psychiatry. 6: e872, 2016. プレスリリース

Fujioka T, Inohara K, Okamoto Y, Masuya Y, Ishitobi M, Saito DN, Jung M, Arai S, Matsumura. Y, Fujisawa TX, Narita K, Suzuki K, Tsuchiya KJ, Mori N, Katayama T, Sato M, Munesue T, Okazawa H, Tomoda A, Wada Y, Kosaka H

OA! ⇒ Gazefinder as a clinical supplementary tool for discriminating between autism spectrum disorder and typical development in male adolescents and adults.

Mol Autism. 7: 19, 2016. プレスリリース

Morita T, Kosaka H, Saito DN, Fujii T, Ishitobi M, Munesue T, Inohara K, Okazawa H, Kakigi R, Sadato N.

Neural correlates of emotion processing during observed self-face recognition in individuals with autism spectrum disorders

Res Autism Spectr Disord. 26: 16-32. 2016.

Okamoto Y, Ishitobi M, Wada Y, Kosaka H.

OA! ⇒ The Potential of Nasal Oxytocin Administration for Remediation of Autism Spectrum Disorders.

CNS & Neurological Disorders-Drug Targets. 15: 564-577. 2016.

Arai S, Okamoto Y, Fujioka T, Inohara K, Ishitobi M, Matusmura Y, Jung M, Kawamura K, Takiguchi S, Tomoda A, Wada Y, Hiratani M, Matsuura N, Kosaka H

Altered frontal pole development affects self-generated spatial working memory in ADHD.

Brain & Development, 38(5): 471-80. 2016.

石飛信、小坂浩隆、神尾陽子

薬物療法と注意点「ASD」

発達障害A to Z, 186-190. 2016.

丁ミンヨン、小坂浩隆

「自閉症スペクトラムのデフォルトモードネットワークと臨床応用」

Clinical Neuroscience, 34巻6号、2016.

石飛信、丁ミンヨン、小坂浩隆

「自閉スペクトラム症の原因はわかったの？ 〜脳画像研究の観点から〜」

チャイルドヘルス, 19(5): 18-22. 2016.

小坂浩隆、岡本悠子

「発達障害の新しい治療法 ～オキシトシンを中心に～」

チャイルドヘルス, .19(5): 27-32. 2016.

小坂浩隆

「注意欠如多動症」 特集 「精神科薬物治療におけるゴール、そして終結は」

臨床精神薬理, 19(3): 295-306, 2016.

大森晶夫、小坂浩隆

「老年期うつ病と認知症の見分け方」 特集「老年期うつ病と認知症 見分け方とケア」

臨床老年看護, 23(1): 2-11, 2016.

Kumazaki H, Muramatsu T, Fujisawa TX, Miyao M, Matsuura E, Okada K, Kosaka H, Tomoda A, Mimura M.

Assessment of olfactory detection thresholds in children with autism spectrum disorders using a pulse ejection system.

Molecular Autism, 2016, 7: 6.

Munesue T, Nakamura H, Kikuchi M, Miura Y, Takeuchi N, Anme T, Nanba E, Adachi K, Tsubouchi K, Sai Y, Miyamoto K, Horike S, Yokoyama S, Nakatani H, Kosaka H, Minabe Y, Higashida H.

Oxytocin for male subjects with autism spectrum disorder and comorbid intellectual disabilities: A randomized pilot study

Frontiers in Psychiatry, 7: 2, 2016.

Fujioka T, Takiguchi S, Yatsuga C, Hiratani M, Hong KEM, Shin MS, Cho S, Kosakak H, Tomoda A.

Advanced Test of Attention in Children with Attention-Deficit/Hyperactivity Disorder in Japan for Evaluation of Methylphenidate and Atomoxetine Effects

Clinical Psychopharmacology and Neuroscience. 14(1): 79-87, 2016.

＝＝＝2015 ＝＝＝

Jung M, Maria M, Saito DN, Tomoda A, Okazawa H, Wada Y, Kosaka H.

OA! ⇒ Sex differences in the default mode network with autism spectrum traits.

PLoS ONE. 10(11):e0143126, 2015.

Shimada K, Fujisawa TX, Takiguchi S, Naruse H, Kosaka H, Okazawa H, Tomoda A.

Ethnic differences in COMT genetic effects on striatal grey matter alterations associated with childhood ADHD: a voxel-based morphometry study in a Japanese sample.

The World Journal of Biological Psychiatry. 18:1-7, 2015.

Takiguchi S, Fujisawa TX, Mizushima S, Saito DN, Okamoto Y, Shimada K, Koizumi M, Kumazaki H,Jung M, Kosaka H, Hiratani M, Ohshima Y, Teicher MH, Tomoda A.

Ventral striatum dysfunction in children and adolescents with reactive attachment disorder: functional MRI study.

British Journal of Psychiatry Open. 1(2):121-128, 2015.

Mizuno K, Takiguchi S, Yamazaki M, Asano M, Kato S, Kuriyama K, Watanabe Y, Sadato N, Tomoda A.

Impaired neural reward processing in children and adolescents with reactive attachment disorder: a pilot study.

Asian Journal of Psychiatry. 17: 89-93, 2015.

Fujisawa TX, Jung M, Kojima M, Saito DN, Kosaka H, Tomoda A.

Neural basis of psychological growth following adverse experiences: A resting-state functional MRI study.

PLoS One. 10(8): e0136427, 2015.

小坂浩隆、岡本悠子、丁ミンヨン

「自閉スペクトラム症の脳画像研究」

精神科, 27(4): 265-270, 2015.

Tomoda A, Takiguchi S, Fujisawa TX, Yatsuga C, Kumazaki H, Fujioka T, Suzuki H, Matsuzaki H, Kosaka H, Tanaka S.

Effectiveness of oral tipepidine administration for children with attention deficit hyperactivity disorder: A 4-week, open-label, phase 1 clinical study

Psychiatry and Clinical Neurosciences. 2015, 69(10): 658-659.

Shimada K, Takiguchi S, Mizushima S, Fujisawa TX, Saito DN, Kosaka H, Okazawa H, Tomoda A.

Reduced visual cortex gray matter volume in children with reactive attachment disorder

NeuroImage Clinical. 9: 13–19, 2015.

丁ミンヨン、小坂浩隆

「自閉症スペクトラムのrs-fMRI」

Clinical Neuroscience, 33(11): 1310-1311, 2015.

岡本悠子、新井清義、齋藤大輔、小坂浩隆

「児童・青年期の脳機能画像研究 ２．fMRI」

児童青年精神医学とその近接領域,56(5): 754-762, 2015.

藤岡徹、村田里佳、石坂郁代、河野俊寛、大石敬子、滝口慎一郎、平谷美智夫

発達性ディスレクシア児の学習面での問題に対する教員の認識についての検討 ～注意欠陥/多動性障害と広汎性発達障害の併存が与える影響について～

LD研究、24(3): 347-355, 2015. ★LD学会研究奨励賞★

Masuya Y, Okamoto Y, Inohara K, Matsumura Y, Fujioka T, Wada Y, Kosaka H.

OA! ⇒ Sex-different abnormalities in the right second to fourth digit ratio in Japanese individuals with autism spectrum disorders.

Mol Autism, 6:34, 2015.

Kumazaki H, Muramatsu T, Kosaka H, Fujisawa TX, Iwata K, Tomoda A, Tsuchiya K, Mimura M.

Sex differences in cognitive and symptom profiles in children with high functioning autism spectrum disorders.

Res Autism Spectr Disord, 13–14:1–7,2015.

Komeda H, Kosaka H, Saito DN, Mano Y, Jung M, Fujii T, Yanaka HT, Munesue T, Ishitobi M, Sato M, Okazawa H.

OA! ⇒ Autistic empathy toward autistic others.

Soc Cogn Affect Neurosci, 10(2):145-52, 2015. プレスリリース

＝＝＝2014 ＝＝＝

Matsuura N, Ishitobi M, Arai S, Kawamura K, Asano M, Inohara K, Fujioka T, Narimoto T, Wada Y, Hiratani M, Kosaka H.

OA! ⇒ Effects of Methylphenidate in Children with Attention Deficit Hyperactivity Disorder: A Near-Infrared Spectroscopy Study with CANTAB.

Child Adolesc Psychiatry Ment Health, 8:273, 2014.

Matsuura N, Ishitobi M, Arai S, Kawamura K, Asano M, Inohara K, Narimoto T, Wada Y, Hiratani M, Kosaka H.

Distinguishing between autism spectrum disorder and attention deficit hyperactivity disorder by using behavioral checklists, cognitive assessments, and neuropsychological test battery.

Asian J Psychiatr, 12:50–57, 2014.

Okamoto Y, Kitada R, Tanabe CH, Hayashi MJ, Kochiyama T, Munesue T, Ishitobi M, Saito DN, Yanaka HT, Omori M, Wada Y, Okazawa H, Sasaki AT, Morita T, Itakura S, Kosaka H, Sadato N.

Attenuation of the contingency detection effect in the extrastriate body area in autism spectrum disorder.

Neurosci Res, 87:66-76, 2014. プレスリリース

Ishitobi M, Kawatani M, Asano M, Kosaka H, Goto T, Hiratani M, Wada Y.

Quetiapine responsive catatonia in an autistic patient with comorbid bipolar disorder and idiopathic basal ganglia calcification.

BRAIN DEV JPN, 36(9):823-5T, 2014.

Fujisawa TX, Tanaka S, Saito DN, Kosaka H, Tomoda A.

Visual attention for social information and salivary oxytocin levels in preschool children with autism spectrum disorders: An eye-tracking study.

Front Neurosci, 8:295, 2014. プレスリリース

Jung M, Kosaka H, Saito DN, Ishitobi M, Morita T, Inohara K, Asano M, Arai S, Munesue T, Tomoda A, Wada Y, Sadato N, Okazawa H, Iidaka T.

OA! ⇒ Default mode network in young male adults with autism spectrum disorder: relationship with autism spectrum traits.

Mol Autism, 5:35, 2014 ★福井大学医学部2014年度前期における 優秀論文賞★ プレスリリース

Asano M, Ishitobi M, Hiratani M, Kosaka H, Wada Y.

Ramelteon monotherapy for insomnia and impulsive behavior in high-functioning autistic disorder.

J CLIN PSYCHOPHARM, 34(3):402-3T, 2014.

Fujii T, Saito DN, Yanaka HT, Kosaka H, Okazawa H.

Depressive mood modulates the anterior lateral CA1 and DG/CA3 during a pattern separation task in cognitively intact individuals: A functional MRI study.

Hippocampus, 24(2):214-24, 2014. ★福井大学医学部2013年度下半期における 優秀論文賞★

石飛信、荻野和雄、小坂浩隆、神尾陽子

特集：注意と精神疾患 I-7 「ASDと注意機能」

精神科, 24(2):178-81T, 2014.

＝＝＝2013 ＝＝＝

Ishitobi M, Kosaka H, Takahashi T, Yatuga C, Asano M, Tanaka Y, Ueno K, Okazaki R, Omori M, Hiratani M, Tomoda A, Wada Y.

Effectiveness and tolerability of switching to aripiprazole from risperidone in subjects with autism spectrum disorders: a prospective open-label study.

Clin Neuropharmacol, 36(5):151-6, 2013.

滝口慎一郎、齋藤大輔、小坂浩隆、友田明美

心の発達の研究最前線：脳科学の観点から－fMRIを中心に

小児内科, 45(8)T, 2013.

Komeda H, Kosaka H, Saito DN, Inohara K, Munesue T, Ishitobi M, Sato M, Okazawa H.

Episodic memory retrieval for story characters in high-functioning autism.

Mol Autism, ;8:295, 2013. ★福井大学医学部2014年度前期における 優秀論文賞★ プレスリリース

小坂浩隆、石飛信、定藤規弘

自閉症スペクトラム障害のfMRI研究

脳21, 16(2):45-51F, 2013.

小坂浩隆、田邊宏樹、守田知代、岡本悠子、齋藤大輔、石飛信、棟居俊夫、和田有司、定藤規弘

「自閉症スペクトラム障害の社会性障害を探る: fMRI 研究」

日本生物学的精神医学会誌, 23(4):255-61F, 2013.

＝＝＝2012 ＝＝＝

Tanabe HC, Kosaka H, Saito DN, Koike T, Hayashi MJ, Izuma K, Komeda H, Ishitobi M, Omori M, Munesue T, Okazawa H, Wada Y, Sadato N.

Hard to “tune in”: neural mechanisms of live face-to-face interaction with high-functioning autistic spectrum disorder.

Front Hum Neurosci, 6:268, 2012. プレスリリース

Narita K, Fujiwara K, Takei Y, Suda M, Aoyama Y, Uehara T, Majima T, Kosaka H, Amanuma M, Fukuda M, Mikuni M.

Associations among parenting experiences during childhood and adolescence, hypothalamus-pituitary-adrenal axis hypoactivity, and hippocampal gray matter volume reduction in young adults.

Hum Brain Mapp, 33(9):2211-23, 2012.

Kosaka H, Munesue T, Ishitobi M, Asano M, Omori M, Sato M, Tomoda A, Wada Y.

OA! ⇒ Long-term oxytocin administration improves social behaviors in a girl with autistic disorder.

BMC Psychiatry, 12(1):110F, 2012.

Ishitobi M, Hiratani M, Kosaka H, Takahashi T, Mizuno T, Asano M, Murata T, Tomoda A, Wada Y.

Switching to aripiprazole in subjects with pervasive developmental disorders showing tolerability issues with risperidone.

PROG NEURO PSYCHOPH, 37(1):128-31, 2012.

Morita T, Kosaka H, Saito DN, Ishitobi M, Munesue T, Itakura S, Omori M, Okazawa H, Wada Y, Sadato N.

Emotional responses associated with self-face processing in individuals with autism spectrum disorders: An fMRI study.

Soc Neurosci, 223-239, 2012.