Vania Silverio

R&D Microfluidics Scientist @ INESC MN  |  Invited Assistant Professor @ Department of Physics, Tecnico, ULisboa

Contact: vsilverio_at_inesc-mn.pt    or   vania.silverio_at_tecnico.ulisboa.pt



Vania Silverio is Senior Researcher at INESC MN, leading the Microfluidics Lab. She is currently involved in scientifically innovative and challenging problems combining nanotechnology with simulation tools for the design, fabrication, integration and test of Microfluidic Platforms, Lab-On-Chip and Organ-on-Chip. Dr Silverio is the Convenor of  ISO/TC 48/WG 3 - Microfluidic Devices for the standardization of Microfluidics. Additionally, she has been nominated as Expert for the definition of Standards and Processes for Microfluidics [CEN/TC 332/WG 7] and for Organ-on-Chip [CEN/CENELEC FGOOC].


She authored several research publications in the areas of fluid dynamics at the microscale and microfluidics device fabrication. She combines her research with service providing and advanced training, teaching and theses supervision at the Master and PhD level at Instituto Superior Técnico, ULisboa (http://tecnico.ulisboa.pt), where she is an Invited Assistant Professor (Microfluidics course; Micro and Nanofabrication Techniques course).


Silverio is regular Peer Reviewer for Scientific Journals and is frequently involved in the organization of International Meetings on Microfluidics and Nanotechnology. She is member of the MFA (The Microfluidics Association), EUROoCS (European Organ-on-Chip Society), IEEE Society USA, EPS (European Physical Society), SPF (Portuguese Physical Society), and IOP (Institute of Physics).

Silverio holds a PhD degree in Mechanical Engineering (Tecnico, ULisboa) and a Licenciatura degree in Technological Chemistry (5 years, FCUL, ULisboa).


Publications:


Pereira MR, Silva G, Semiao V, Martins JNR, Silverio V, Pascoal-Faria P, Duarte I, Alves N, Ginjeira A (2023) 

Syringe irrigation in confluent canals: A sequential computational fluid dynamics assessment

Australian Endodontic Journal 00:1–12. DOI: 10.1111/aej.12805


Fonseca CG, Silverio V, Barata D, Giese W, Gerhardt H, Cardoso S, Franco CA (2023) 

A 96-wells fluidic system for high-throughput screenings under laminar high wall shear stress conditions

Microsystems & Nanoengineering 9, Article number 114. DOI: 10.1038/s41378-023-00589-x 


Gil JF, Moura CS, Silverio V, Gonçalves G, Santos HA (2023) 

Cancer models on chip: paving the way to large scale trial applications 

Advanced Materials 2300692, 26 pp. DOI: 10.1002/adma.202300692 


Caetano DM, Afonso R, Soares AR, Silva J, Busse HI, Silverio V, Rabuske T, Tavares G, Fernandes JR, Cardoso S (2023) 

Artificial Neural Networks for GMR-Based Magnetic Cytometry

IEEE Transactions on Instrumentation & Measurement 72:1-11, Art no. 2506911, DOI: 10.1109/TIM.2023.3244208 

 

Silverio V, Canane PAG, Martins TA, Afonso R, Cardoso S, Batista E (2022) 

Development of a microfluidic electroosmosis pump on a chip for steady and continuous fluid delivery

Biomedical Engineering/Biomedizinische Technik. DOI: 10.1515/bmt-2022-0051

   

Lopes C, Cristóvão J, Silverio V, Lino PR, Fonte P (2022) 

Microfluidic production of mRNA-loaded lipid nanoparticles for vaccine applications 

Expert Opinion on Drug Delivery 19(10):1381-1395. DOI: 10.1080/17425247.2022.2135502


Pereira MR, Silva G, Semiao V, Silverio V, Martins JNR, Pascoal-Faria P, Alves N, Dias JR, Gingeira A (2022)

Experimental validation of a computational fluid dynamics model using micro-particle image velocimetry of the irrigation flow in confluent canals

International Endodontic Journal. DOI: 10.1111/iej.13827 

 

Silverio V, Guha S, Keiser A, Natu R, Reyes DR, van Heeren H, Verplanck N, Herbertson LH (2022)

Overcoming Technological Barriers in Microfluidics: Leakage Testing 

Frontiers in Bioengineering and Biotechnology, 10:958582. DOI: 10.3389/fbioe.2022.958582


van Heeren H, Silverio V, Pecnik C, Batista E. (2022)

Metrology Challenges for Microfluidics 

Commercial Micro Manufacturing Magazine, April 13


Tombelli S, Trono C, Berneschi S, Berrettoni C, Giannetti A, Bernini R, Persichetti G, Testa G, Orellana G, Salis F, Weber S, Luppa PB, Porro G, Quarto G, Schubert M, Berner M, Freitas PP, Cardoso S, Franco F, Silverio V, Lopez-Martinez M, Hilbig U, Freudenberger K, Gauglitz G, Becker H, Gärtner C, O’Connell MT, Baldini F (2021)
An integrated device for fast and sensitive immunosuppressant detection
Analytical & Bioanalytical Chemistry, DOI: 10.1007/s00216-021-03847-x


Batista E, Metaxiotou Z, Graham E, Timmerman A, Andreia Furtado A, Lotters J, Silverio V (2020)
Report: COVID-19 Crisis & Emergency Practices – Infusion Pumps in ICU: The Role of Metrology
Euramet 18HLT08 MeDDII - Metrology for drug delivery II: selected by the European Commission as a core project in addressing the need for hospital and personal protective equipment. http://www.drugmetrology.com

Batista E,  Sousa J A, Cardoso S, Silverio V (2020)
Experimental testing for metrological traceability and accuracy of liquid microflows and microfluidics
Flow Measurement and Instrumentation 71:101691 (6 pp), DOI: 10.1016/j.flowmeasinst.2020.101691

Silverio V, Amaral M, Gaspar J, Cardoso S, Freitas PP (2019)
Manipulation of Magnetic Beads with Thin Film Microelectromagnet Traps
Micromachines 10(9):607 (16 pp), DOI: 10.3390/mi10090607

Silverio V, Canane PAG, Cardoso S (2019)
Surface wettability and stability of chemical modified silicon, glass and polymeric surfaces via room temperature chemical vapor deposition
Colloids and Surfaces A: Physicochemical and Engineering Aspects, 570:210-217, DOI: 10.1016/j.colsurfa.2019.03.032

Soares R, Martins VC, Macedo R, Cardoso FA, Martins SAM, Caetano DM, Fonseca PH, Silverio V, Cardoso S, Freitas PP (2019)
Go with the flow: advances and trends in magnetic flow cytometry, Invited Review
Analytical and Bioanalytical Chemistry 411(9):1839–1862, DOI: 10.1007/s00216-019-01593-9

Silverio V, Silva AV, Przykaza K, Santos LF, Melo LV, Cardoso S (2019)
Dark Matters: Black-PDMS nanocomposite for opaque microfluidic systems
Physical Chemistry Chemical Physics, 21:2719-2726, DOI: 10.1039/C8CP06828C

Silverio V, López-Martínez MJ, Franco F, Amaral M, Gaspar J, Cardoso S, Freitas PP (2017)
On-chip magnetic nanoparticle manipulation and trapping for biomedical applications
IEEE Transactions on Magnetics 53(11):5100806 (6 pp), DOI: 10.1109/TMAG.2017.2715848

Cardoso S, Leitao DC, Dias T, Valadeiro J, Silva M, Chicharo A, Silverio V, Gaspar J, Freitas PP (2017)
Challenges and trends in magnetic sensor integration with microfluidics for biomedical applications. Invited Topical Review highlighted in JPhys+
Journal of Physics D: Applied Physics 50:213001 (12 pp), DOI: 10.1088/1361-6463/aa66ec

Silverio V, Cardoso S, Gaspar J, Freitas PP, Moreira ALN (2015)
Design, fabrication and test of an integrated multi-microchannel heatsink for electronics cooling
Sensors and Actuators A: Physical 235:14-27, DOI: 10.1016/j.sna.2015.09.023



Book Chapters:


Silverio V, Cardoso S (2023) 

Magnetically actuated systems for microfluidic applications

In Chiriac H, Lupu N (Eds.), Magnetic Sensors and Actuators in Medicine 

Elsevier, ISBN: 978-0-12-823294-1


Silverio V, Cardoso S (2021)
Lab-on-a-chip: systems integration at the microscale
in Chappel E (Ed), Drug Delivery Devices and Therapeutic systems 

Elsevier Science, DOI: 10.1016/B978-0-12-819838-4.00020-1

Cardoso S, Silverio V (2021)
Introduction to microfabrication techniques for microfluidics devices
in Chappel E (Ed), Drug Delivery Devices and Therapeutic systems
Elsevier Science, DOI: 10.1016/B978-0-12-819838-4.00026-2


Silverio V, Cardoso de Freitas S (2018)
Microfabrication Techniques for Microfluidic Devices
in Galindo-Rosales FJ (Ed.) Complex Fluid-Flows in Microfluidics
Springer International Publishing, DOI: 10.1007/978-3-319-59593-1_2



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