standards for Microfluidics
Standardization groups
ISO/TC 48/WG 3 - Microfluidic devices. link
CEN/TC 332/WG 7 - Micro Process Engineering. link
CEN/CENELEC FGOOC (Focus Group on Organ on Chip). link
Research Projects
MFMET - Establishing Metrology Standards in Microfluidic Devices. link
MeDD II - Metrology for Drug Delivery. link
Papers in Scientific Journals
V. Silverio, S. Guha, A. Keiser, R. Natu, D.R. Reyes, H. van Heeren, N. Verplanck, L.H. Herbertson (2022) Overcoming Technological Barriers in Microfluidics: Leakage Testing. Frontiers in Bioengineering and Biotechnology, 10: 958582, https://doi.org/10.3389/fbioe.2022.958582
D.R. Reyes, H. van Heeren. Proceedings of the first workshop on standards for microfluidics. Journal of Resesearch of the National Institute of Standards and Technology, 124 (2019) 124001, https://doi.org/10.6028/jres.124.001
H. van Heeren. Standards for connecting microfluidic devices? Lab on a Chip, 12 (2012) 1022–1025, https://doi.org/10.1039/C2LC20937C
Articles in the News
MSD Staff Writer. Setting the standard. Medical Device Developments. November 18, 2022. link
NS Energy Staff Writer. Setting the standard. NS Medical Devices, November 02, 2022. link
H. van Heeren. The lack of standard metrology tools impedes the pace of microfluidics development. Photonics, May 20, 2022. link
H. van Heeren, V. Silverio, C. Pecnik, E. Batista. Metrology Challenges for Microfluidics. Commercial Micro Manufacturing Magazine, April 13, 2022. link
White papers for Industry - The Microfluidics Association
van Heeren H, Silverio V, Batista E, Reyes D (Jan 2024) On the road to standardization in Microfluidics and Organ-on-Chip. link
van Heeren H, Pecnik C, Silverio V, Batista E, Yin H, Akselli B, Ogheard F (May 2023) Common microfluidic components materials: properties and fabrication. link
Copeland M, Ogheard F, Batista E, van Heeren H (May 2023) Flow resistivity testing. link
Pecnik C, van Heeren H, Yin H (Apr 2023) Guidelines for Optical Interfaces of Microfluidic Devices. link
Akselli B, Batista E, Furtado A, van Heeren H, Moura S, Ogheard F, Pecnik C, Silverio V, Yin H, Zhang N, Zhao H (Oct 2022) Measurement of hydrophobicity, hydrophilicity, and wettability. link
Crouzier L, Pecnik C (Dec 2022) Test protocol surface roughness [Protocol]. link
van Heeren H, Davies M, Keiser A, Lagrauw R, Reyes DR, Silverio V, Verplanck N (May 2022) Protocols for leakage testing [White paper]. link
Microfluidic Vocabulary, version 5.0 (May 2019). link
Guidelines for Electrical Interconnections to Microfluidic Devices, version 1.0 (Oct 2017). link
Design for Microfluidic Interfacing, White Paper, Part 1, Version 3.0 (Jun 2017). link
Design for Microfluidic Interfacing, White Paper, Part 2, Version 3.0 (Jun 2017). link
Design Guidelines for Microfluidic Side Connect, version 1.0 (Jun 2017). link
ISO Standards - International Organization for Standardization
ISO/DTS 6417 Microfluidic pumps — Symbols and performance communication. link
ISO/10991:2023 Micro process engineering — Vocabulary. link
ISO 22916:2022 Microfluidic devices — Interoperability requirements for dimensions, connections and initial device classification. link
IWA 23:2016 Interoperability of microfluidic devices — Guidelines for pitch spacing dimensions and initial device classification. link
Workshops on Microfluidics Standards
Standardization of Test Methods in Microfluidics (2024), IPQ, 22 May, Caparica, Portugal, link
On the road to standardization in microfluidics and organ-on-chip (2023), CETIAT, 13 - 14 November, Lyon, France, link
Putting Science into Standards (2021), European Commission Joint Research Centre and the European Standardization Organizations CEN and CENELEC , 28 – 29 April, Virtual, link, link
6th Microfluidics Standards Workshop: De-Risking Microfluidic Product Development, October 9 & 10, 2019, Coronado, CA, USA, link
5th Workshop on Microfluidics Standards (2019), INESC MN, 26 – 27 March, Lisboa Portugal, link, link
4th Workshop on Microfluidics Standards (2018), METAS, 11 – 12 July, Bern, Switzerland, link
3rd Workshop on Microfluidics Standards (2018), CEA LETI, 6 – 7 March, Grenoble, France, link, link
2nd Workshop on Microfluidics Standards (2017), Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017, 22 – 26 October, Georgia, USA, link
1st Workshop on Microfluidics Standards (2017), NIST, 1 – 2 June, Maryland, USA, link
Microfluidic Standardization (2016), International MicroNanoConference 2016, 13 December, Amsterdam, The Netherlands, link, link
