CARTOGEN

CARTOGEN Tablet

Promotes collagen synthesis in joint cartilage

CARTOGEN Tablet is a scientific combination of effective ayurvedic drugs that promote collagen synthesis in joint cartilage.

PHARMACOLOGY OF INGREDIENTS

CARTOGEN Tablet ingredients have been reported to - (1) Promote collagen synthesis in joint cartilage; and (2) Antioxidant, and (3) Anti-aging as follows –

Ashvagandha (Withania somnifera) ext. (300 mg) – Ashvagandha is a widely used rasayana (antioxidant, anti-aging, and regenerative) in ayurveda. Bhav-prakash describes it as kshaya-apaha (regenerative), rasayani (rejuvenating and antioxidant), balya (immunomodulating), and shotha-apaha (anti-inflammatory). All these actions indicate that it helps regeneration of degenerating tissues (including joint cartilage). These actions have been reported by Mishra LC et al, too. Bh. Pr. Ni. Gud. 189-90; Mishra LC et al. Alt. Med. Rev. Vol 5 (4), pp. 334-346, 2000.

Shilajatu sh. (215 mg) – Shilajatu has been used as an excellent rasayana in ayurveda. Bhav-prakash describes it as rasayana (rejuvenating and antioxidant), kshaya-hara (regenerative), and shotha-hara (anti-inflammatory) indicating its significant role in the degenerating tissues (including joint cartilage). Mittal et al have reported rejuvenating, free radical scavenging, antioxidant, immuno-modulating, anti-inflammatory, analgesic in shilajatu. Bh. Pr. Ni. Dhat. 78-82; Mittal et al. IJPCR, Vol 1 (2), pp 47-49, 2009.

Mandukparni (Centella asiatica) ext. (175 mg) – Bhav-prakash describes Mandukparni as ayushya (anti-aging), rasayani (rejuvenating and antioxidant), shotha-hara (anti-inflammatory), and asrajit (corrects micro-circulation). Lee J et al have reported that asiaticoside in (Centella asiatica) induces human collagen I synthesis through TGFbeta receptor I kinase (TbetaRI kinase)-independent Smad signaling. Bh. Pr. Ni. Gud. 279-81; Lee J, et al. Planta Med 72:324–328, 2006.

Dugdhika (Euphorbia thymifolia) ext. (100 mg) – Bhav-prakash describes it ruksha (anti-obesity) and ushna (metabolic stimulant) both of which help in weight reduction quite often found in patients with osteo-arthritis. Bh. Pr. Ni. Gud. 275-76.

Yashad (Zinc) bhasma (10 mg) - Yashad has been described in ayurveda as an dhātu-vardhaka (antioxidant that promotes regeneration of tissues) and rasapinda-vikriti-nashaka (immune-modulator) - R.T.S.S.P.S. p. 129.

SUMMARY OF ACTIONS

• Promotes collagen synthesis in joint cartilage
• Rejuvenating
• Anti-oxidant and free radical scavenging
• Anti-inflammatory and analgesic

INDICATIONS

On the basis of the actions of its individual ingredients CARTOGEN Tablet is indicated as an adjunct in the prevention and management of:

Degenerative Joint Diseases (DJD) - Osteo-arthritis (OA) of the knee, hip, shoulder, ankle, and other joints

Spondylosis – Cervical spondylosis and lumbar spondylosis

Disc Disorders – Prolapse of the inter-vertebral disc, dessication of the IV disc, and sciatica

DOSAGE SCHEDULE:

Initial dose: 1 tablet 3 times a day

Maintenance dose: 1 tab 1-2 times a day.

To be swallowed with water, just after/within meals.

Buy CARTOGEN online at

www.sandeepniayurveda.in