The Cuatro is a four-string instrument from Venezuela. It is often used for playing a folk style of music called "Joropo".
It is used in Venezuela and East Colombia.
The B string is tuned one octave lower than expected. This is called the "re-entrant tuning".
Some performers prefer the higher A4 tuning for the 4th string. This is called the "linear tuning" (but is prune to breakage).
There are also some alternative tunings, which we won't cover here.
To produce different notes, press a string on one of the frets with the left hand, and pluck it with the right hand.
The following chart shows the notes produced by each string, when pressed on each fret: