High Intensity Focused Ultrasound for prostate carcinome
Minimal invasive transrectal treatment for localized prostate cancer.
HIFU delivers focused ultrasound energy via a transrectal U.S. probe - under transrectal ultrasound guidance - causing rapid
thermal necrosis of tissue within the target area without damaging the surrounding tissue. HIFU is the least invasive curative
treatment alternative to radical prostatectomy.
Objectives : to present the preliminary clinical results on our first 200 T1-2 ( 3a) N0M0 prostate cancer patients, treated
with transrectal High Intensity Focused Ultrasound ( HIFU ). PSA outcome and comorbidity are analysed.
Method : 180 patients with biopsy proven localized prostate cancer T1-T3a have been treated with HIFU over a period of 28
months, using the Ablatherm HIFU unit ( Edap –Technomed ). The clinical outcome of the first 200 patients with a mean follow-up
of 12 months ( 3 – 24 ) have been analysed.
Results : 95 % of patients had PSA < 1 ng/ml within 3 months ; 82 % of T1-2 patients had a nadir PSA < 0.5 ng/ml at 1 month
upto > 12 months after single HIFU treatment. No major complications were seen, urethral or bladderneck stricture or sloughing
was seen in 10 % of patients. Temporary stress I-II / urge incontinence was seen in 17 % of patients, recovering within 3
months in 98 % of them. 82 % of patients with cancer limited to 1 lobe who had a focal nerve sparing therapy on their request
remained potent after the HIFU session, 25 % of patients after complete HIFU treatment.
Conclusion : Hifu proves to be a safe, minimal invasive and possibly curative treatment option for patients with localized
prostate cancer. Continued monitoring of follow-up studies is mandatory.
... Sofar our FIRST published experience with HIFU.
In the mean time we have treated > 1200 patients succesfully and have 15 years of follow-up and experience ! See posters on international congresses below and on the Dutch ( "Nederlands" ) page.
International HIFU training center : if you are a urologist / last year resident and intersted to follow a HIFU training , HIFU demonstration ( follow a treatment session ) or follow-up training masterclass, do not hesitate to contact us : chris_dhont@hotmail.com
Invest in THE and YOUR future and optimize your patients care
We are ready to teach you how to perform correct HIFU treatments and how to avoid pitfalls and inconveniences and reduce learningcurves for new centers worldwide.
For new centers we assure local training and teaching + assistance at your first treatments - after a base teaching in our center - together with a team of EDAP specialists and further post training treament and teaching assistance, worldwide.
Our experience : > 1000 treatments and > 10 years of follow up ( since october 2000 ), international patient population, internatinal HIFU centers training, start-up and assistance.
Specialists advise and expertise in case of problems.
For more information: chris_dhont@hotmail.com
How does it work ? : see video
see update posters ( in English ) and presentations in the Dutch ( "Nederlands" ) section under "HIFU"
Indications for a safe truly minimal invasive HIFU treatment with full respect to Quality Of Life :
- curative : Localized / locally advanced T1-3a prostate cancers with no metastases
Options : Full, bejond the capsula for T3a, Nerve-sparing uni- or bilateral, hemiablation, focal treatment : according to the
individual tumor situation, tumor site and extension, aggressiveness and patient's wishes
- salvage curative : in case of local recurrence after any former primary treatment
- palliative : curative treatment of the primary tumor = better controll and QuOL of the metastases
FDA approved since nov 2015