Aortic Endograft & Device Migration

Aortic Endograft & Device Migration: Long-term durability of endovascular aortic aneurysm repair is uncertain due to the presence of endoleaks and endograft migration. The biomechanics of endograft migration involves strong coupling of fluid (blood) and structure (endograft, artery wall) along with mechanical (endograft composition, oversizing) and bio-mechanical (hemodynamics, aneurysm tortuosity, fixation length) factors. We have developed a comprehensive framework for understanding endograft migration including realistic patient anatomy, device geometry, material models, and in-vivo forces combining tools from computational solid mechanics (CSM) and computational fluid dynamics (CFD).

References:

1. Prasad A, Xiao N, Gong XY, Zarins CK, Figueroa CA (2012). A Computational Framework for Investigating the Positional Stability of Abdominal Endografts (accepted, Biomechanics in Modeling and Mechanobiology). [pdf].

2. Prasad A, Gong XY, Figueroa CA, Zarins CK (2011). A Finite Element Approach for Evaluating the Risk of Endograft Migration. ASME 6^th Frontiers in Biomedical Devices Conference and Exhibition, Irvine, CA, USA (Invited presentation).