Research

Affordable Blood Pressure Monitoring in Low resource setting (under Indo-US challenge Grant, 2014-2017): We are focusing on development of Cuffless Non-invasive measurement using radial artery. The team (project PI: Dr Anamika Prasad) consists of students and faculty from AIIMS-New Delhi and IIT-Delhi.

The focus of development as defined by the challenge call is: "Hypertension diagnosis and management is a critical healthcare need in both the U.S. and India, and is an area that is ripe for technological innovation. New technologies could be utilized in the design of innovative, low-cost blood pressure measurement devices that remove the need for blood-pressure cuffs and trained medical personnel, which is currently the only option to diagnose and manage hypertension for the vast majority of individuals worldwide. The development of new and affordable devices that can be accurately and easily used by patients in their homes, or in localized health care settings, could substantially improve the diagnosis and management of hypertension in both countries."

Biomechanics of Extracorporreal Irradiation Therapy in Malignant Bone Tumor: Extracorporeal irradiation therapy (ECRT) and reimplantation is now an established technique for limb salvage surgery of malignant bone. ECRT is a biological reconstruction method with several advantages including no risk of immunological reaction or diseases transmission, cost-effective,absence of heavy implants, no need for subsequent surgeries in growing-age patients, and others.While several studies have focused on clinical outcome of the procedure, structural and changes in human bone under heavy dose of radiation (50 Gy) are not well established. Here we examine clinical outcome and pre and post ECRTbiomechanical property (structure, composition, and mechanical) of bone for patients with malignant bone tumors and Ewing’s sarcoma). (details)

This work received Technical Edge Appreciation under Gandhian Young Technology Innovation 2015

Finite Element Stress Analysis of Development Dysplasia of Hip (DDH): Hip dislocation when left untreated can lead to progressive degenerative disease later in life. In India and other developing countries, due to reduced awareness and absence f well-baby checkup, the problem and interventions typically happen later in (> 2 years of age). At this age, treatment methods and outcome are strongly dependent on patient's age and is primarily based on qualitative assessment of operative vs untreated risk analysis. In this study, we perform stress analysis of patient cases suffering from DDH to quantify and compare joint reaction force of the normal contact vs the dislocated contact to help in better decision making and care.

Device for Compliance and Early-relapse Detection for clubfoot: With close collaboration with AIIMS clubfoot clinic, we are developing a novel sole for monitoring of compliance and detection of early signs of relapse. Figure shows child undergoing clubfoot procedure (top) and the bracing used and early prototype of the sensor circuit (bottom). The sole embedded pressure sensors location at the forefoot (metatarsal bone) and the heel section are based on the clinical observation of early signs of relapse observed at the heel section. The pressure reading on the two location is stored using an SD card module, and will be available to the physician through mobile application. The electronics will be packaged inside an add-on sole or can be fitted as an attachment to the brace.