Recent Publications
The Role of Dafachronic Acid Signaling in Development and Longevity in Caenorhabditis elegans: Digging Deeper Using Cutting Edge Analytical Chemistry. Hugo Aguilaniu, Paola Fabrizio and Michale Witting. 2016 Frontiers in Endocrinology of Aging. in press
The mysterious relationship between reproduction and longevity. Aguilaniu H. Worm. 2015 Mar 6;4(2):e1020276. doi: 10.1080/21624054.2015.1020276. eCollection 2015 Apr-Jun.
Fast separation and quantification of steroid hormones Δ4- and Δ7-dafachronic acid in Caenorhabditis elegans. (2015). J. Chromatogr. B Analyt. Technol. Biomed. Life. Sci. 978-979C, 118–121.
Steroid hormone signalling links reproduction to lifespan in dietary-restricted Caenorhabditis elegans. Thondamal, M, Wittiing, M, Schmitt-Kopplin, P., and Aguilaniu H. Nature Communications 2014 Sep 11; 5: 4879
Reproduction, Fat Metabolism, and Life Span: What Is the Connection? Hansen, M., Flatt, T., and Aguilaniu, H. Cell Metabolism 2013 17, 10–19.
Aging Yeast Undergo a Sharp Transition to Senescence Unrelated to the Loss of Mitochondrial Membrane Potential. Fehrmann, S., Paoletti, C., Goulev, Y., Ungureanu, A., Aguilaniu, H., Charvin, H. (2013). Cell Reports 2013 Dec 10.
Fatty acid desaturation links germ cell loss to longevity through NHR-80/HNF4 in C. elegans. Goudeau J, Bellemin S, Toselli-Mollereau E, Shamalnasab M, Chen Y,Aguilaniu H. PLoS Biol. 2011 Mar;9(3) - Marked MUST READ by Faculty of 1000.
Carbonylated proteins are eliminated during reproduction in C. elegans. Goudeau J, Aguilaniu H. Aging Cell. 2010 Dec;9(6):991-1003. Marked MUST READ by Faculty of 1000.
PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans. Panowski SH, Wolff S, Aguilaniu H, Durieux J, Dillin A. Nature. 2007 May 31;447(7144):550-5
Elimination of damaged proteins during differentiation of embryonic stem cells. Hernebring M, Brolén G, Aguilaniu H, Semb H, Nyström T. Proc Natl Acad Sci U S A. 2006 May 16;103(20):7700-5.
Metabolism, ubiquinone synthesis, and longevity. Aguilaniu H, Durieux J, Dillin A. Genes Dev. 2005 Oct 15;19(20):2399-406. Review.