Ch. 13: RNA and Protein Synthesis

Messenger RNA, transfer RNA, and ribosomal RNA work together in prokaryotic and eukaryotic cells to translate DNA’s genetic code into functional proteins. These proteins, in turn, direct the expression of genes.

13.1 RNA

The main differences between RNA and DNA are that (1) the sugar in RNA is ribose instead of deoxyribose; (2) RNA is generally single-stranded, not double-stranded; and (3) RNA contains uracil in place of thymine. In transcription, segments of DNA serve as templates to produce complementary RNA molecules.

13.2 Ribosomes and Protein Synthesis

The genetic code is read three “letters” at a time, so that each “word” is three bases long and corresponds to a single amino acid. Ribosomes use the sequence of codons in mRNA to assemble amino acids into polypeptide chains. The central dogma of molecular biology is that information is transferred from DNA to RNA to protein.

13.3 Mutations

Mutations are heritable changes in genetic information. The effects of mutations on genes vary widely. Some have little or no effect; some produce beneficial variations. Some negatively disrupt gene function. Mutations often produce proteins with new or altered functions that can be useful to organisms in different or changing environments.

Below are several interesting videos that will help you gather a better understanding of what RNA is and how it works.