Program

Day 1st.

Dec. 25th

8:30-9:00 Waiting room open

8:50-8:55 Official Announcement

Moto Nishida (host)

8:55-9:00 Opening remarks

Prof. Kurose (organizer)

[Oral Session 1 (Rising-Sun Symposium)]

Chairs: Jin Han (Inje University)

Kazuhiro Nishiyama (Kyushu University)

9:00- 9:25

Taichiro Tomida

(Toho University, Japan)

Regulatory mechanism of cell fusion in skeletal myogenesis

9:30-9:55

Hiroyuki Kawagishi

(Shinshu University, Japan)

Postnatal loss of gp130 caused impaired cardiac contractility accompanied by inhibition of physiological proliferation of cardiomyocytes

10:00- 10:25

Teruki Sato

(Akita University, Japan)

B38-CAP is a bacteria-derived carboxypeptidase which resembles SARS-CoV-2 receptor ACE2 enzyme activity and suppresses hypertension and cardiac dysfunction in mice

10:30- 10:55

Ippei Shimizu

(Niigata University, Japan)

Senocule-induced sync-aging promotes pathologies in cardiovascular disorders

10:55- 11:10 Break

[Memorial Lecture I]

Chair: Motohiro Nishida

11:10- 11:55

Ryuji Inoue

(Fukuoka University, Japan)

From receptor-operated Ca2+ channels to TRP channels

–my personal challenge to understanding elusive but fascinating molecules-


11:55- 12:30 Lunch Break

[ Luncheon Seminar]

12:00- 12:20

Hyoung Kyu Kim

(Inje University, South Korea)

Tetrahydrobiopterin enhanced cardiac mitochondrial biogenesis via NOS-independent CaMKK2/PGC-1α pathway

[Oral Session 2 (Rising-Sun Symposium)]

Chairs: Mitsuhiko Yamada (Shinshu University)

Akiyuki Nishimura (NIPS/ExCELLS, NINS)

12:30- 12:55

Supachoke Mangmool

(Mahidol University, Thailand)

Adenosine Receptor: Therapeutic Target for Treatment of Cardiac Fibrosis

13:00- 13:25

Amira Hajirah Abd Jamil

(University of Malaya, Malaysia)

Energy Metabolism in the Hypoxic and Diabetic hearts

13:30- 13:55

Yun Seok Kim

(Seoul Natl Univ. / Dongguk Univ., South Korea)

LXRα Inhibition of Autophagy in Hepatocytes: Impact on Fatty Liver Disease

14:00- 14:25

Yukiko Himeno

(Ritsumeikan University, Japan)

Reproducing variable action potential configurations of hiPS-CMs by applying parameter optimization to a mathematical cardiomyocyte model

14:25- 14:40 Break

[Oral Session 3]

Chairs: Keiji Kuba (Akita University)

Tomohiro Tanaka (CNSI/NIPS/ExCELLS, NINS)

14:40- 15:05

Woong Sun

(Korea University, South Korea)

Prevention of mitochondrial impairment by inhibition of protein phosphatase 1-Drp1 cascade in amyotrophic lateral sclerosis

15:10- 15:35

Mariko Omatsu-Kanbe

(Shiga Univ. of Med. Sci., Japan)

Property and possible role of cardiac progenitors atypically-shaped cardiomyocytes

15:40- 16:05

Jin Han

(Inje University, South Korea)

BH4 activates CaMKK2 and rescues the cardiomyopathic phenotype in rodent models of diabetes

16:05- 16:15 Break

[Short talks 1]

Chairs: Hitoshi Kurose (Kyushu University)

Takuro Numaga-Tomita (Shinshu University)

16:15-:16:25 Koji Sakata (Miyazaki University)

Modulation of cardiac function by intervention in the regulatory mechanisms of actin dynamics in the sarcomere


16:25- 16:35 Sayaka Oda (NIPS/ExCELLS/SOKENDAI, NINS)

TRPC6 positively regulates cardiac contractility by modulating β adrenergic receptor signaling


16:35- 16:45 Yoshinori Mikami (Toho University)

Cardioprotective effect of insulin on left ventricular diastolic dysfunction of diabetic cardiomyopathy through direct and indirect pathways


16:45- 16:55 Yukari Takeda (Fukui University)

Spatial and functional associations of mitochondria and local calcium release in murine sinoatrial nodal cells


16:55- 17:05 Soumyadip Pal (Osaka University)

Screening for factors causing the morphological remodelling of mitochondrial nucleoids


17:05- 17:15 Yuki Hanada (Osaka University / Kyushu University)

Regulatory mechanism of mitochondrial immune response against RNA virus infection


17:15- 17:25 Yung-Ting Hsiao (Niigata University)

Cardiac Mitofusin-1 is Declined in Non-responding Patients with Heart failure


17:25- 17:35 Tomoyuki Kojima (Yokohama City University)

Implantable tissue engineered blood vessels fabricated by periodic hydrostatic pressure

17:35- 17:45 Break

[Short talks 2]

Chairs: Satomi Adachi-Akahane (Toho University)

Yuri Kato (Kyushu University)

17:45- 17:55 Yuri Kato (Kyushu University)

Involvement of TRPC3-Nox2 axis in ACE2-mediated SARS-CoV-2 infection in hearts


17:55- 18:05 Xinya Mi (Shiga Univ. of Med. Sci.)

Functional role of delayed rectifier K+ current in the spontaneous automaticity of the guinea-pig pulmonary vein cardiomyocytes


18:05- 18:15 Ryo Fukunaga (Shiga Univ. of Med. Sci.)

Presence of ANP promotor-driven AcGFP-expressing cardiac progenitor cells in mice heart


18:15- 18:25 Yuki Tsukano (Niigata University)

Obesity associated Pro-Fibrotic Protein Augments Fibrosis in Heart


18:25- 18:35 Yohko Yoshida (Niigata University)

Brown adipose tissue dysfunction promotes metabolic disorder in a failing heart.


18:35- 18:45 Shota Tanifuji (Tokyo Medical University)

Three-dimensional multilayers of smooth muscle cells acquire arterial physiology


18:45- 18:55 Junko Kurokawa (University of Shizuoka)

Sex differences in functional morphology of the murine fetal heart

18:55- 19:30

Free Discussion

Day 2nd.

Dec. 26th

8:30-9:00 Waiting room open

8:55- 9:00 Official Announcement

Moto Nishida (host)

[Oral Session 4]

Chairs: Yasunari Kanda (NIHS, Japan)

Moto Nishida (Kyushu Univ./NIPS/ExCELLS)

9:00- 9:25

Tsukasa Shimauchi

(Laval University, Canada)

Role of PARP1-PKM2 axis in the pathogenesis of Right Ventricular Failure associated with Pulmonary Arterial Hypertension

9:30- 9:55

Naotada Ishihara

(Osaka Univ. / Kurume Univ., Japan)

Dynamic regulation of mitochondrial membrane in cellular signaling and differentiation

10:00- 10:25

Shigeru Yanagi

(Gakushuin University, Japan)

Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation

10:30- 10:55

Wataru Kimura

(RIKEN, Japan)

Metabolic adaptation in the regulation of cardiomyocyte cell cycle ~how mammals deal with a mismatch between development and birth timing?

10:55- 11:10 Break

[Memorial Lecture II ]

Chair: Motohiro Nishida

11:10- 11:55

Hitoshi Kurose

(Kyushu University, Japan)

G protein selectivity of antagonists

11:55- 12:00 Closing remarks

Prof. Hitoshi Kurose

12:00- 12:05 Announcement

Prof. Mitsuhiko Yamada (Next Organizer)