care-uk
CARE-UK
CPMS ID: IRAS ID: 325928
A novel reliever strategy for children with asthma: Children’s Anti-inflammatory Reliever study, United Kingdom (CARE-UK). To determine the clinical effectiveness, safety and cost-effectiveness of budesonide-formoterol reliever therapy either alone or as part of maintenance and reliever therapy (MART) compared with SABA reliever therapy either used as monotherapy or with the child’s usual maintenance treatment in children with asthma aged ≥4 to <12 years.
Updated 10/07/2024
Inclusion Criteria
1. Clinician diagnosis of asthma
2. Prescribed asthma medication in past 6 months (SABA, ICS or ICS+LABA)
3. Parent or carer able to understand the study requirements and willing to provide informed consent
Exclusion Criteria
1. Other chronic airways disease including but not limited to bronchiectasis, cystic fibrosis, sickle cell disease
2. Already using ICS-formoterol as a reliever
3. Children on step 5, very high dose treatment (e.g. high dose ICS/LABA, prescription of biological therapy such as omalizumab)
4. Any known or suspected contraindications to the medications prescribed in the study or their respective excipients
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