Bioengineered muscle tissue matrix and its effects on various markers of myogenesis. Observable upregulation of ɑ-skeletal actin mRNA expression of C2C12 cells grown on muscle matrix. Observed promotion of differentiation in samples grown on muscle tissue matrices.
Foundational information regarding myogenesis and the expression of ɑ- and β-actin during the myoblast stage and the formation of myotubes.
Information regarding the observed effects of ECM-derive protein coatings on the growth of cells during myogenesis
Cell-laden hydrogel constructs produced using direct-write bioprinting technology can be used to guide parallel growth and alignment of C2C12 cells during myogenesis.
Advanced maturation by electrical stimulation: Differences in response between C2C12 and primary muscle progenitor cells
β-actin is downregulated during myogenic differentiation.
Reference paper for ECM-derived fibronectin and gelatin protein coatings on culture plates for culturing C2C12 myoblasts.