Establish clearly defined work hours and stick to them (most of the time when working from home, your work hours can be flexible to meet the needs of your family life).
Create a work space that is comfortable (avoid using your bedroom as you want your brain to continue to associate this room with sleep and relaxation).
Create small transitions to signal the start and end of work (this used to be the commute to work).
Minimize distractions so you can stay focused and conduct yourself with professionalism.