Unit 9

UNIT 9: GENETIC ENGINEERING

IN THIS UNIT WE WILL LOOK AT SOME OF THE AMAZING THINGS WE CAN DO AS A RESULT OF THE HUMAN GENOME PROJECT. STUDENTS WILL LEARN ABOUT DNA FINGERPRINTING, TRANSGENIC ORGANISMS, RECOMBINANT DNA, AND APPLICATIONS OF GENETIC ENGINEERING. ALSO IN THIS UNIT STUDENTS WILL EVALUATE THE ETHICS ASSOCIATED WITH GENETIC ENGINEERING TECHNIQUES. BE PREPARED TO BE AMAZED, AS THIS IS A FAVORITE UNIT FOR MOST STUDENTS!

North Carolina Standard Course of Study

Bio.3.3 Understand the application of DNA technology.

Bio.3.3.1 Interpret how DNA is used for comparison and identification of organisms.

• Summarize the process of gel electrophoresis as a technique to separate molecules based on size. Students should learn the general steps of gel electrophoresis – using restrictions enzymes to cut DNA into different sized fragments and running those fragments on gels with longer fragments moving slower than faster ones.

• Interpret or “read” a gel.

• Exemplify applications of DNA fingerprinting - identifying individuals; identifying and cataloging endangered species.

Bio.3.3.2 Summarize how transgenic organisms are engineered to benefit society.

•Generalize the applications of transgenic organisms (plants, animals, & bacteria) in agriculture and industry including pharmaceutical applications such as the production of human insulin.

• Summarize the steps in bacterial transformation (insertion of a gene into a bacterial plasmid, getting bacteria to take in the plasmid, selecting the transformed bacteria, and producing the product).

Bio.3.3.3 Evaluate some of the ethical issues surrounding the use of DNA technology (including cloning, genetically modified organisms, stem cell research, and Human Genome Project).

• Identify the reasons for establishing the Human Genome Project.

• Recognize that the project is useful in determining whether individuals may carry genes for genetic conditions and in developing gene therapy.

• Evaluate some of the science of gene therapy. (e.g. Severe Combined Immunodeficiency and Cystic Fibrosis)

• Critique the ethical issues and implications of genomics and biotechnology (stem cell research, gene therapy and genetically modified organisms)

Tuesday, November 12 - DNA Fingerprinting Online Interactive

DNA Online Interactive

Tuesday, November 12 - DNA Fingerprinting

How is DNA Fingerprinting Done Video

How is DNA fingerprinting used to identify a criminal KS3 animation from Activate 3 Kerboodle.mp4

DNA Fingerprinting Paternity Video

DNA FINGERPRINTING PATERNITY.mp4

Monday, April 30

Transformation Webquest

Tuesday, May 1 - Applications of Genetic Engineering

Applications of Genetic Engineering

Glow in the dark cat image taken from: https://www.qut.edu.au/institute-for-future-environments/about/news/news?news-id=125657