FAQs
Q: Who can use the High Throughput Screening facility?
A: Both academia and industry investigators can request the service.
Q: What services does the HTS facility provide? What are the fees?
A: Please visit the "Available Services" page. Check here for the fees.
Q: How to request a service?
A: Please visit the "Fees and Make a Request" page.
Q: What is the status of your compound? what is the final DMSO concentration?
A: Our compounds are solubilized in 100% DMSO and reformated to be 1 mM stock in online 1536-well plate.
Q: Can I purchase the compounds from core facility?
A: The compounds have been reformatted in 384- and 1536-well plates. We can provide structure and provider information for the investigator to make a purchase. For special requests, please contact us.
Q: Screening service is so expensive.
A: Considering the number of tested samples and the usage of reagent, the cost of a screening service is economical.
Q: What concentration of compounds will be used in the screening? How many times?
A: Primary screening will be conducted ONE single concentration, 10 uM if not specified.
Q: High-throughput screening fails to find leads.
A: The hit-rate of a screening is usually 0.1%~0.3%. HTS is only the beginning of the hit-to-lead process, which requires combination efforts in a variety of areas.