FAQs

Q: Who can use the High Throughput Screening facility?
A:  Both academia and industry investigators can request the service.

Q: What services does the HTS facility provide? What are the fees?

A: Please visit the "Available Services" page. Check here for the fees. 

Q: How to request a service?

A: Please visit the "Fees and Make a Request" page. 

Q: What is the status of your compound? what is the final DMSO concentration?
A: Our compounds are solubilized in 100% DMSO and reformated to be 1 mM stock in online 1536-well plate.

Q: Can I purchase the compounds from core facility?
A: The compounds have been reformatted in 384- and 1536-well plates. We can provide structure and provider information for the investigator to make a purchase. For special requests, please contact us.

Q: Screening service is so expensive.
A: Considering the number of tested samples and the usage of reagent, the cost of a screening service is economical. 

Q: What concentration of compounds will be used in the screening? How many times?
A: Primary screening will be conducted ONE single concentration, 10 uM if not specified. 

Q: High-throughput screening fails to find leads.
A: The hit-rate of a screening is usually 0.1%~0.3%. HTS is only the beginning of the hit-to-lead process, which requires combination efforts in a variety of areas.