Macromolecular Library Screening

Provides assistance in screening using library of RNAi , CRISPR, antibody, or enzyme variants.

Screening using library of RNAi/CRISPR, antibody, or enzyme variants are useful tools in elucidation of molecular function of interested genes, identification of high-affinity antibodies, and improve function of enzymes, respectively. 

To increase the screening efficiency, the core facility can provide assistances in (1) plating the cells (after infection of expression library) into wells of 384- or 1536-well plates; (2) subsequent luciferase-based or enzymatic assay for functional screening.