研究業績

原著論文

2009

1. Ishikawa, K., Akiyama, T., Ito, K., Semba, K., Inoue, J.: Independent stabilizations of polysomal Drg1/Dfrp1 complex and non-polysomal Drg2/Dfrp2 complex in mammalian cells. Biochem. Biophys. Res. Comm. 390 552-556 (2009)
2. Hattori, M., Iwase, N., Furuya, N., Tanaka, Y., Tsukazaki, T., Ishitani, R., Maguire, M.E., Ito, K*., Maturana, A*., Nureki, O*.: Mg2+-dependent gating of bacterial MgtE channel underlying Mg2+ homeostasis. EMBO J. 28 3602-3612 (2009)
3. Hattori M., Jin Y., Nishimasu H., Tanaka Y., Mochizuki M., Uchiumi T., Ishitani R., Ito K. and Nureki O.: Structural basis of novel interactions between the small-GTPase and GDI-like domains in prokaryotic FeoB iron transporter. Structure. 17: 1-11 (2009)
4. Tsuboi, M., Morita, H., Nozaki, Y., Akama, K., Ueda, T., Ito, K., Nierhaus, K.H., Takeuchi, N.: EF-G2mt is an Exclusive Recycling Factor in Mammalian Mitochondrial Protein Synthesis. Mol Cell. 35: 502-510 (2009)
5. Osawa, T., Ito, K., Inanaga, H., Nureki, O., Tomita, K., Numata, T.: Conserved Cysteine Residues of GidA Are Essential for Biogenesis of 5-Carboxymethylaminomethyluridine at tRNA Anticodon., Structure. 17 713-724 (2009)
6. Cheng, Z., Saito, K., Pisarev, A.V., Wada, M., Pisareva, V.P., Pestova, T.V., Gajda, M., Round, A., Kong, C., Lim, M., Nakamura, Y., Svergun, D.I., Ito, K.*, Song, H.*, Structural insights into eRF3 and stop codon recognition by eRF1, Genes and Development. 23 1106-1118 (2009)

2008

1. Thi Phuong Kim, O., Sakurai, A. Saito, K., Ito, K., Ikehara, K., Harumoto, T.: Ciliates use both variant and universal genetic codes: An evidence of omnipotent eRF1s in the class Litostomatea. Gene 417 51-58 (2008)

2007

1. Kodama, H., Ito, K., Nakamura, Y.: The role of N-terminal domain of translational release factor eRF3 for the control of functionality and stability in S. cerevisiae. Genes Cells. 5 639-650 (2007)
2. Motohashi, R., Yamazaki, T., Myouga, F., Ito, T., Ito, K., Satou, M., Kobayashi, M., Nagata, N., Yoshida, S., Nagashima, A., Tanaka, K., Takahashi, S., Shinozaki, K.: Chloroplast ribosome release factor 1 (AtcpRF1) is essential for chloroplast development. Plant Mol Biol. 64 481-497 (2007)
3. Li, X., Yokota, T., Ito, K., Nakamura, Y., Aiba, H.: Reduced action of polypeptide release factors induces mRNA cleavage and tmRNA tagging at stop codons in Escherichia coli. Mol Microbiol. 63: 116-126 (2007)

2006

1. Sato, H., Ito, K., Nakamura, Y.: Ribosomal protein L11 mutations in two functional domains equally affect release factors 1 and 2 activity. Mol Microbiol. 60, 108-120 (2006)

2005

1. Yamami, T., Ito, K., Fujiwara, T., Nakamura, Y.: Heterologous expression of Aquifex aeolicus ribosome recycling factor in Escherichia coli is dominant lethal by forming a complex that lacks functional co-ordination for ribosome disassembly. Mol Microbiol. 55, 150-161 (2005)

2004

1. Karamyshev, A.L., Karamysheva, Z.N., Yamami, T., Ito, K., Nakamura, Y.: Transient idling of posttermination ribosomes ready to reinitiate protein synthesis. Biochimie. 86: 933-938 (2004)
2. Fujiwara, T., Ito, K., Yamami, T., Nakamura, Y.: Ribosome recycling factor disassembles the post-termination ribosomal complex independent of the ribosomal translocase activity of elongation factor G. Mol Microbiol. 53: 517-28 (2004)
3. Kong, C., Ito, K., Walsh, M.A,, Wada, M., Liu, Y., Kumar, S., Barford, D., Nakamura, Y., Song, H.: Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe. Mol Cell 14: 233-245 (2004)

2003

1. Karamysheva. Z.N., Karamyshev, A.L., Ito, K., Yokogawa, T., Nishikawa, K., Nakamura. Y., Matsufuji, S.: Antizyme frameshifting as a functional probe of eukaryotic translational termination. Nucleic Acids Res 31: 5949-5956 (2003)
2. Polacek, N., Gomez, M.J., Ito, K., Xiong, L., Nakamura, Y., Mankin, A.: The Critical Role of the Universally Conserved A2602 of 23S Ribosomal RNA in the Release of the Nascent Peptide during Translation Termination. Mol. Cell 11: 103-112 (2003)

2002

1. Blake, B.K., Ito, K., Nakamura, Y., Alam, S.L.: Backbone 1H, 13C, and 15N assignments of the ribosome recycling factor from Thermus thermophillus. J Biomol NMR 24: 81-82 (2002)
2. Kervestin, S., Garnier, O.A., Karamyshev, A.L., Ito, K., Nakamura, Y., Meyer, E., Jean-Jean, O.: Isolation and expression of two genes encoding eukaryotic release factor 1 from Paramecium tetraurelia. J Eukaryot Microbiol 49:374-382 (2002)
3. Ito, K., Frolova, L., Seit-Nebi, A., Karamyshev, A., Kisselev, L., Nakamura, Y.: Omnipotent decoding potential resides in eukaryotic translation termination factor eRF1 of variant-code organisms and is modulated by the interactions of amino acid sequences within domain 1. Proc Natl Acad Sci USA 99: 8494-9499 (2002)
4. Ito, K., Fujiwara, T., Toyoda, T., Nakamura, Y.: Elongation factor G participates in ribosome disassembly by interacting with ribosome recycling factor at their tRNA-mimicry domains. Mol Cell 9:1263-1272 (2002)
5. Nakamura, Y., Ito, K.: A tripeptide discriminator for stop codon recognition. FEBS Lett. 514: 30-33 (2002)
6. Uno, M., Ito, K., Nakamura, Y.: Polypeptide release at sense and noncognate stop codons by localized charge-exchange alterations in translational release factors. Proc Natl Acad Sci USA 99: 1819-1824 (2002)

2001

1. Fujiwara, T., Ito, K., Nakamura, Y.: Functional mapping of ribosome-contact sites in the ribosome recycling factor: a structural view from a tRNA mimic. RNA 7: 64-70 (2001)
2. Gong F., Ito K., Nakamura Y., Yanofsky C.: The mechanism of tryptophan induction of tryptophanase operon expression: tryptophan inhibits release factor-mediated cleavage of TnaC-peptidyl-tRNA(Pro) Proc Natl Acad Sci USA 98: 8997-9001 (2001)

2000

1. Tin, O.F., Ryukonova, A.I., Muranova, T.A., Toyoda, T., Ito, K., Suzuki, T., Watanabe, K., Garber, M.B., Nakamura, Y.: Proteolytic fragmentation of polypeptide release factor 1 of thermus thermophilus and crystallization of the stable fragments. Biochimie. 82: 765-772 (2000)
2. Toyoda, T., Tin, O.F., Ito, K., Fujiwara, T., Kumasaka, T., Yamamoto, M., Garber, M.B., Nakamura, Y.: Crystal structure combined with genetic analysis of the Thermus thermophilus ribosome recycling factor shows that a flexible hinge may act as a functional switch. RNA 7: 1432-1444 (2000)
3. Wilson, K.S., Ito, K., Noller, H.F., Nakamura, Y.: Functional sites of interaction between release factor RF1 and the ribosome. Nat Struct Biol. 7: 866-870 (2000)
4. Ito, K., Uno, M., Nakamura, Y.: A tripeptide 'anticodon' deciphers stop codons in messenger RNA. Nature 403: 680-684 (2000)