inDesign

  1. To apply the drop cap to a single paragraph, choose Drop CapsAnd Nested Styles from the Paragraph panel menu.
  2. To nest the character style in a paragraph style, double-click the paragraph style, and then click Drop Caps And Nested Styles.
  3. See more at https://helpx.adobe.com/indesign/using/drop-caps-nested-styles.html

-Version inDesign CC 2019, and 2020

Adding a drop cap: Go to the text tool , then choose the paragraph icon- choose the number of letters and rows that you want.