Embedded Files
Steps involved in translation of prokaryotes – role of proteasomes in protein degradation – mechanism of action of antibiotics on protein synthesis (puromycin, chloramphenicol and streptomycin). Regulation of gene expression in prokaryotes – polycistronic mRNA and operons (lac operon and trp operon and attenuation mechanism).
Steps involved in translation of prokaryotes – role of proteasomes in protein degradation – mechanism of action of antibiotics on protein synthesis (puromycin, chloramphenicol and streptomycin). Regulation of gene expression in prokaryotes – polycistronic mRNA and operons (lac operon and trp operon and attenuation mechanism).
portions shown in bold need to be self prepared as assignment
Video and Text Resources
To understand about the steps in translation click HERE, and a detailed information about translation click HERE
To know about the arrangement of the Shine-Dalgarno sequence and Kozak sequence click HERE; To know about aminoacyl tRNA synthetase activity click HERE and for the structure of tRNA Link 1 and Link 2
To know about the role of proteasome in protein degradation click HERE and to understand Ubiquitin proteasome pathway click HERE
A clear explanation on the mechanism of action of translation inhibiting antibiotics viz. Puromycin, chloramphenicol and Streptomycin click HERE
For an introductory lecture related to regulation of gene expression in prokaryotes (in Tamil) click HERE
To understand about the lac operon click HERE (simple video) for an detailed explanation click HERE and for an explanation (in Tamil) click HERE
To know about the Trp operon (repressor) click HERE and for the Trp attenuation explanation click HERE for another video explaining the Trp attenuation click HERE
# Scientific literatures reading is for your understanding and knowledge, may not be important from the examination point of view
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