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DNA replication in prokaryotes: Replicons – models of DNA replication – origin and termination of replication – rolling circle replication – proof for semi conservative replication (Meselson and Stahl Experiment) – enzymes and proteins involved in DNA replication (nucleases, polymerases, ligases, helicases, gyrases, single strand binding protein, replisome and primosome) – mechanism of semi discontinuous replication.
DNA replication in prokaryotes: Replicons – models of DNA replication – origin and termination of replication – rolling circle replication – proof for semi conservative replication (Meselson and Stahl Experiment) – enzymes and proteins involved in DNA replication (nucleases, polymerases, ligases, helicases, gyrases, single strand binding protein, replisome and primosome) – mechanism of semi discontinuous replication.
Video Lectures (Watch the video files with headphone for audio clarity and note the points in course journal (CJ), and get it signed by the course teacher) To find the key points that should be there in CJ, click HERE
Video Lectures (Watch the video files with headphone for audio clarity and note the points in course journal (CJ), and get it signed by the course teacher) To find the key points that should be there in CJ, click HERE
To understand about the process of replication (includes Replicon - models of DNA replication - Bidirectional replication / theta model /Cairns model of DNA replication -
Lect 1A (Intro & three possible models of DNA replication) and
Lect 1B (Bidirectional/Cairns model or theta replication)
Overall steps in DNA replication explained in Tamil, click for Part-1 and Part-2 (Courtesy: Biology Simplified Tamil)
To understand, Rolling circle/sigma replication & linear DNA molecule replication in Eukaryotes - Lect 2; Rolling circle replication explained in Tamil, click HERE
Proof for Semi conservative replication (Meselson & Stahl Experiment) click HERE; for one more simple explanation click HERE; Meselson-Stahl experiment explained (in Tamil) click HERE
Introduction to enzymes & proteins involved in DNA replication, including Nucleases - Lect 3
- For an explnation in Tamil related to DNA replication related enzymes and proteins, click HERE
- The complete DNA replication explanation (in 5 min) in tamil click HERE
Enzymes & proteins involved in DNA replication viz. DNA Gyrases and Helicases - Lect 4
Enzymes & proteins involved in DNA replication viz. SSBP, Primases, Preprimosome & Primosome - Lect 5
Enzymes & proteins involved in DNA replication viz. DNA polymerases types - Lect 6
Enzymes & proteins involved in DNA replication viz. DNA poly -III, eukaryotic DNA polymerases, ligase & Replisome - Lect 7
Mechanism of semiconservative replication - Lect 8
For an explanation of semiconservative replication in Tamil click HERE
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