DEC 4: Examining Tooth Metals & the Gut Microbiome in a Birth Cohort

posted Nov 26, 2018, 11:27 AM by Anna Cronenwett

Wayne County Health, Environment, Allergy & Asthma Longitudinal Study (WHEALS): 

Dec 4 | 12:00 pm | 3755 School of Public Health I  
Univ of MI Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD)
  • Andrea Cassidy-Bushrow, MPH, PhD (Associate Scientist, Dept. of Public Health Sciences, Henry Ford Health System) 
  • Sponsored by M-LEEaD's Integrated Health Sciences Core

Freida Blostein presents poster at MEEGID 2018

posted Nov 8, 2018, 8:30 AM by Anna Cronenwett   [ updated Nov 12, 2018, 1:41 PM ]

Doctoral student, Freida Blostein, presented her poster "Herpesvirus acquisition in infancy: association with the salivary microbiome?" at the 14th International Meeting on Molecular Epidemiology and Evolutionary Genetics of Infectious Diseases (MEEGID XIV), held at Melia Sitges, Sitges, Spain, 6-9 November 2018.

Elyse Davis Presents Poster at ACE Meeting 2018

posted Sep 25, 2018, 7:52 AM by Anna Cronenwett

MAC-EPID student, Elyse Davis, presented her poster about Vancomycin Resistant Enterococcus (VRE) on Monday at the American College of Epidemiology's (ACE) annual meeting.

Elyse is getting her MPH in Epidemiology. 

MAC-EPID has a paper published in the Journal of Global Antimicrobial Resistance

posted Apr 13, 2018, 9:00 AM by Anna Cronenwett   [ updated Nov 12, 2018, 1:45 PM ]


Journal of Global Antimicrobial Resistance

Volume 13, June 2018, Pages 81-84
Journal of Global Antimicrobial Resistance

Association of Escherichia coli ST131 lineage with risk of urinary tract infection recurrence among young women

Miriam D.Ismail1, IhsanAli2, SavannahHatt, Elizabeth A.Salzman, Anna W.Cronenwett, Carl F.Marrs, Alexander H.Rickard, Betsy Foxman
The Center for Molecular and Clinical Epidemiology of Infectious Diseases (MAC-EPID), Department of Epidemiology, University of Michigan, School of Public Health, Ann Arbor, MI 48109, USA

Dissertation Defense of Ting Luo, April 12th, 1pm, M1170 SPH II

posted Apr 10, 2018, 10:04 AM by Anna Cronenwett

The University of Michigan
Department of Epidemiology
Presents the
Dissertation Defense

Ting Luo, MPH
speaking on

Algorithms & Techniques for Studying In Vitro Oral Biofilms 
Thursday, April 12, 2018
1:00 – 2:00pm
Room M1170 SPH II
All interested persons are cordially invited

Dental caries and periodontal disease affects billions of people worldwide with an estimated global prevalence of 35% and 11%, respectively. Oral biofilms that develop on tooth surfaces and within gingival crevices are a major risk factor. Disease prevention efforts are focused on controlling the overgrowth of biofilms by removal (e.g., tooth brushing), antimicrobial-containing mouth rinses, and dentifrices. A number of laboratory (in vitro) models of biofilms are used to understand how biofilms develop and their response to mouth rinses and dentifrices.

However, there are two major limitations to currently available in vitro biofilm model systems. First, there is no biofilm model system validated for the development of representative dental plaque biofilms. Second, there is no standard approach to analyze biofilm images. Current techniques rely on thresholding algorithms that are not designed for fluorescent images. Combined, these limitations can lead to differences in quantification of biofilm outcomes and thus raise questions regarding the relevance of the model system to the real-world.

This dissertation seeks to bridge the gap between current laboratory techniques and software algorithms and provide investigators complementary protocols to conduct in vitro oral biofilm studies. First, we provided a review of existing model systems relevant to modern in vitro oral biofilm research. Second, we adapted the 24-well Bioflux, the most versatile of the reviewed systems, to reproducibly grow multi-species dental biofilms seeded from human saliva. Additionally, we devised an objective imaging strategy to capture all biofilm architectural features. From the analytical perspective, we designed a novel thresholding algorithm, the biovolume elasticity method (BEM) to threshold fluorescent signal. Finally, we built a software package called Biofilm Architecture Inference Tool (BAIT) to measure core architectural features of biofilms.

In summary, this dissertation describes the modification of a 24-well Bioflux system that facilitates the reproducible development of oral biofilms. The BAIT package, featuring the novel BEM thresholding technique, enables investigators to quickly quantify an array of biofilm architectural descriptors. Understanding change and continuity in biofilm architecture after treatment can identify potential new agents of biofilm control. The work presented here represents the outcome of a combinatorial approach to redefine techniques to study oral biofilms which may be relevant to the study and analysis of all biofilms that have been fluorescently labeled.


posted Apr 2, 2018, 10:21 AM by Anna Cronenwett   [ updated Apr 2, 2018, 10:36 AM ]

Applications due April 23, 2018

Washington Post cites Foxman about cranberries

posted Mar 29, 2018, 8:35 AM by Anna Cronenwett   [ updated Mar 29, 2018, 8:47 AM ]

"Big Cranberry Juice: We can stop UTIs. Science: Maybe." by Caitlin Dewey, March 16, 2018

Dr. Foxman's study "Preventing Urinary Tract Infection (UTI) Post Surgery (P.U.P.S.)" looked at the effect of cranberry capsules on the rate of UTI in women after gynecological surgery.  View study on

Vote for Michigan to win STAT Madness today!

posted Feb 28, 2018, 7:40 AM by Anna Cronenwett   [ updated Mar 29, 2018, 8:29 AM ]

Thank you to all who supported our team and got us so far!  ECU managed to take the win this time but what a ride! 
Here are some photos of the Michigan Medicine team.  GO BLUE!

updated Mar 22, 2018, 11:17 AM

We are slowly closing the gap (ECU 50%, UM 49%) but we only have until midnight tonight. 
Please VOTE to send us on to the semi-finals!

updated Mar 20, 2018, 1:49 PM

We need your help!  
We are falling behind East Carolina University in the 4th round (see below).  
Please vote often (you can vote again after 5 minutes).  
The round ends at midnight on Thursday, March 22.

updated Mar 13, 2018, 4:44 PM

That was close, thank you for voting!  We are in round 3 against North Carolina State University.  Remember, you can vote daily from each browser and computer!  Please vote often and help us win!

updated Mar 8, 2018, 12:53 PM

We are falling behind and need your help! Click on the image to vote by midnight tonight (you can vote daily, just click "vote again").

updated Mar 6, 2018, 8:33 AM

Thank you to all who voted, we beat NYU!  Next we're up against Texas.
Please click on the image to vote by midnight Thursday, March 8.

posted Feb 28, 2018, 10:40 AM 

"Network of microbial and antibiotic interactions drive colonization and infection with multidrug-resistant organisms" by MAC-EPID members Joyce Wang, Betsy Foxman, Lona Mody and Evan Snitkin was selected to represent University of Michigan in the STAT Madness tournament.  Set up similar to the NCAA tournament March Madness papers from each school go head to head until only one remains.  
We need your votes by midnight tomorrow (March 1) to win the first round against NYU.  
To view a summary of the papers being voted on hover over the school icon then click "View Matchup."  Click "Read More" to view full article.

ITiMS applications due Thursday

posted Feb 27, 2018, 11:17 AM by Anna Cronenwett

ITiMS apps due March 1! Come to info session Feb 20, 12-1:30

posted Feb 19, 2018, 2:04 PM by Anna Cronenwett

Applications to this integrated training program are due March 1, 2018.  Come to this information session put on by current ITiMS students to learn more about the program.  

The Integrated Training in Microbial Systems (ITiMS) program offers mentorship and financial support to University of Michigan doctoral students exploring the burgeoning field of microbiome studies. We aim to train future scientists who will design and implement novel prevention, diagnostic, and treatment strategies stemming from a deep understanding of the impact of microbial communities on human and environmental health.

While the program’s interdisciplinary workshops, trainings, and events are open to all master's and doctoral students, doctoral students are eligible to apply for an ITiMS traineeship (tuition and stipend). 

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