2020 (7 papers)
γ‐aminobutyric acid stimulates β‐cell proliferation through the mTORC1/p70S6K pathway, an effect amplified by Ly49, a novel γ‐aminobutyric acid type A receptor positive allosteric modulator Untereiner A et al Diabetes Obes Metab 22:2021, 2020
The magnesium transporter NIPAL1 is a pancreatic islet-expressed protein that conditionally impacts insulin secretion Manialawy et al J Biol Chem 295:9879, 2020
Human islets contain a subpopulation of glucagon-like peptide-1 secreting α cells that is increased in type 2 diabetes Campbell SA et al Mol Metab 39:101014, 2020
Glucose-dependent partitioning of arginine to the urea cycle protects β-cells from inflammation Fu A et al Nat Metab 2:432, 2020
GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human beta cell regeneration Ackeifi C and Wang P et al Sci Transl Med 12:eaaw9996, 2020
Multimodal imaging probe development for pancreatic beta-cells: from fluorescence to PET Kang NY et al J Am Chem Soc 142:3430, 2020
Luseogliflozin increases beta cell proliferation through humoral factors that activate an insulin receptor- and IGF1 receptor-independent pathway Shirakawa J and Tajima K et al Diabetologia 63:577, 2020