2022 (8 papers)
Beta-cell mass expansion during puberty involves serotonin signaling and determines glucose homeostasis in adulthood Castell A-L et al JCI Insight 7:e160854, 2022
E2F1 transcription factor mediates a link between fat and islets to promote β-cell proliferation in response to acute insulin resistance Shirakawa J et al Cell Rep 41:111436, 2022
Glucose-dependent miR-125b is a negative regulator of β-cell function Cheung R and Pizza G et al Diabetes 71:1525, 2022
Uncoupling protein 2 and aldolase B impact insulin release by modulating mitochondrial function and Ca2+ release from the ER Inoue R et al iScience 25:104603, 2022
Calcium-dependent transcriptional changes in human pancreatic islet cells reveal functional diversity in islet cell subtypes Yoon JS et al Diabetologia 2022 Retracted on August 04, 2023
Disrupting the DREAM complex enables proliferation of adult human pancreatic beta cells Wang P et al J Clin Invest 32:e157086, 2022
Heterogenous impairment of α-cell function in type 2 diabetes is linked to cell maturation state Dai X-Q et al Cell Metab 34:256, 2022
Exendin-4 stimulates autophagy in pancreatic β-cells via the RAPGEF/EPAC-Ca2+-PPP3/calcineurin-TFEB axis Zummo FP et al Autophagy 2022 18:799, 2022