2011 (11 papers)
Beta-cell uncoupling protein 2 regulates reactive oxygen species production, which influences both insulin and glucagon secretion Robson-Doucette CA et al Diabetes 60:2710, 2011
cMyc is a principal upstream driver of beta-cell proliferation in rat insulinoma cell lines and is an effective mediator of human beta-cell replication Karslioglu E et al Mol Endocrinol 25:1760, 2011
AEB071 (sotrastaurin) does not exhibit toxic effects on human islets in vitro, nor after transplantation into immunodeficient mice Merani S et al Islets 3:338, 2011
The caspase inhibitor IDN-6556 (PF3491390) improves marginal mass engraftment after islet transplantation in mice McCall M et al Surgery 150:48, 2011
Id3 upregulates BrdU incorporation associated with a DNA damage response, not replication, in human pancreatic β-cells Lee SH et al Islets 3:358, 2011
Recognition and killing of human and murine pancreatic beta cells by the NK receptor NKp46 Gur C et al J Immunol 187:3096, 2011
The Id3/E47 axis mediates cell-cycle control in human pancreatic ducts and adenocarcinoma Lee SH et al Mol Cancer Res 9:782, 2011
Glucose regulates cyclin D2 expression in quiescent and replicating pancreatic β-cells through glycolysis and calcium channels Salpeter SJ et al Endocrinology 152:2589, 2011
Human islet distribution program for basic research at a single center Kin T et al Transplant Proc 43:3195, 2011
The adult mouse and human pancreas contain rare multipotent stem cells that express insulin Smukler SR et al Cell Stem Cell 8:281, 2011
SUMOylation regulates insulin exocytosis downstream of secretory granule docking in rodents and humans Dai XQ et al Diabetes 60:838, 2011