2015 (10 papers)
The IRE1α/XBP1s pathway is essential for the glucose response and protection of β cells Hassler JR et al PLoS Biol 13:e1002277, 2015
Augmented Stat5 signaling bypasses multiple impediments to lactogen-mediated proliferation in human beta cells Chen H et al Diabetes 64:3784, 2015
Transcript expression data from human islets links regulatory signals from genome-wide association studies for type 2 diabetes and glycemic traits to their downstream effectors van de Bunt M and Manning Fox JE et al PLoS Genet 11:e1005691, 2015
Rp-cAMPS prodrugs reveal the cAMP dependence of first-phase glucose-stimulated insulin secretion Schwede F and Chepurny OG et al Mol Endocrinol 29:988, 2015
Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional beta cells Ferdaoussi M and Dai X et al J Clin Invest 125:3847, 2015
Characterization of zinc influx transporters (ZIPs) in pancreatic beta cells: roles in regulating cytosolic zinc homeostasis and insulin secretion Liu Y et al J Biol Chem 290:18757, 2015
Human islet function following 20 years of cryogenic biobanking Manning Fox JE et al Diabetologia 58:1503, 2015
A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication Wang P et al Nat Med 21:383, 2015
A prevascularized subcutaneous 'Device-Less' site for islet and cellular transplantation Pepper A et al Nat Biotechnol 33:518, 2015
Potential factors for the differentiation of ES/iPS cells into insulin-producing cells Tsugata T et al Cell Med 7:83, 2015