CV (and publications at the bottom)

Curriculum Vitae

Greg J. Hermann

PRESENT ADDRESS:
Department of Biology
Lewis and Clark College
615 S. Palatine Hill Rd.
Portland, Oregon 97219-7899
phone: (503) 768-7568
e-mail: hermann@lclark.edu

EDUCATION:
1998 Ph.D., Biology
University of Utah
Salt Lake City, Utah

1992 B.S., Biology, Magna Cum Laude
Gonzaga University
Spokane, Washington

PROFESSIONAL EXPERIENCE:
2013-present Professor
Department of Biology
Lewis and Clark College
Portland, Oregon

2016-2017, 2012-2014 Chair of Biology
Lewis & Clark College
Portland, OR

2010-2012 Director of Molecular Biology and Biochemistry Program
Lewis and Clark College
Portland, Oregon

2007-2013 Associate Professor
Department of Biology
Lewis and Clark College
Portland, Oregon

2001-2007 Assistant Professor
Department of Biology
Lewis and Clark College
Portland, Oregon

1998-2001 Postdoctoral research with Dr. James Priess
"Organogenesis of the Caenorhabditis elegans Intestine"
Division of Basic Sciences
Fred Hutchinson Cancer Research Center and Howard Hughes Medical Institute
Seattle, Washington

1993-1998 Graduate research with Dr. Janet Shaw
"Genetic Analysis of Mitochondrial Inheritance and Morphology in Yeast"
Department of Biology
University of Utah
Salt Lake City, Utah

1991-1992 Undergraduate research with Dr. Peter Pauw
"Role of the Na+-K+ ATPase During Muscle Development"
Department of Biology
Gonzaga University
Spokane, Washington

GRANTS/AWARDS:
2021-2024 National Science Foundation
“RUI: Investigating the pathways and regulation of lysosome-related organelle biogenesis”

2021-2024 co-PI National Science Foundation
"MRI: Acquisition of a benchtop cell sorter to advance undergraduate research and training in biology at Lewis & Clark College"

2016-2021 National Institutes of Health
“R15-AREA: Rab activation by ABC proteins during lysosome-related organelle biogenesis”

2016-2021 National Science Foundation
"RUI: Investigating the mechanisms regulating the formation of lysosome-related organelles"

2014 HOPES Award from American Society for Biochemistry & Molecular Biology
"Implementing an active learning module using RNAi in C. elegans" in collaboration with Amy Lindahl at Grant High School

2013-2016 co-PI National Science Foundation
“MRI: Acquisition of a laser scanning confocal microscope to advance research and training in biology, chemistry, and physics at Lewis & Clark College”

2012 Council on Undergraduate Research: Outstanding Biology Mentor Award

2011-2015 National Science Foundation
"RUI: Investigating the mechanism of GLO-1 Rab function in C. elegans lysosome-related organelle biogenesis"

2009-2012 National Science Foundation
"MRI: Acquisition of a fluorescence deconvolution microscope for research and training at Lewis & Clark College"

2007-2011 National Science Foundation
"RUI: Cellular and genetic analysis of lysosome and lysosom-related organelle biogenesis in C. elegans"

2005-2007 Murdock College Research Program for Life Sciences
"Investigating a monoclonal antibody that recognizes late-stage apoptotic cells in C. elegans"

2004-2006 Murdock Partners in Science Program "
Genetic analysis of lysosome assembly in C. elegans"

2003-2007 National Science Foundation
"RUI: Genetic and molecular analysis of lysosome assembly and stability in C. elegans"

2002-2004 Murdock College Research Program for Life Sciences
"Investigating the regulation of the Notch receptor, LIN-12, and the Delta ligand, APX-1, during left-right asymmetry in C. elegans organogenesis"

1999-2001 Runyon-Winchell Fellowship
Cancer Research Fund of the Damon Runyon-Walter Winchell Foundation

1998 Riser Dissertation Award
University of Utah

1995-1998 Predoctoral Genetics Training Grant
National Institutes of Health

1995-1996 Graduate Research Fellowship
University of Utah

INVITED SEMINARS:
2018 "Constructing cell-type specific organelles during embryogenesis" Department of Biochemistry and Molecular Biology, Colorado State University

2016 “Constructing cell type-specific organelles during embryogenesis” Department of Biology, Western Washington University

2014 "Roles for Rab GTPases and the HOPS complex during protein trafficking to C. elegans lysosome-related organelles", Department of Biochemistry, University of Washington

2014 "Lysosome related organelle biogenesis in C. elegans" Lysosome-Related Organelles, Zing Meeting, Nerja Spain

2012 "Not all lysosomes are created equal: Genetic analysis of lysosome-related organelle biogenesis in C. elegans" School of Biological Sciences; Victoria University of Wellington, New Zealand

2010 "Genetic analysis of lysosome-related organelle formation and size regulation in C. elegans" Department of Biology; Willamette University

2009 "Genetic analysis of lysosome biogenesis in C. elegans" Department of Cell & Developmental Biology; OHSU

2006 "Organogenesis of the C. elegans intestine: differentiation and biogenesis of specialized lysosomes" Biology Department Seminar; Portland State University

2005 "Genetic analysis of lysosome biogenesis in C. elegans" 15th International C. elegans Meeting; UCLA

2004 "Performing original research in an undergraduate teaching lab" West Coast C. elegans Meeting; UCSB

2003 "Teaching and research at a primarily undergraduate institution" Biosciences Career Symposium; University of Utah

2003 "Organogenesis of the C. elegans intestine: A new twist on Notch signaling" Biology Department Seminar; Reed College

2003 "Left-right asymmetry and organ placement" Natural Sciences Seminar Series; Western Oregon University

2000 "Notch Signaling Controls Left-Right Asymmetry of the C. elegans Intestine" Seattle Development Group; Fred Hutchinson Cancer Research Center

2000 "How Do You Build an Organ? Organogenesis of the Intestine in C. elegans" Gonzaga University

2000 "Left-right Asymmetry in C. elegans Intestine Organogenesis Involves a LIN-12/Notch Signaling Pathway" West Coast C. elegans Meeting; UCLA

INVITED REVIEWS:
Hermann, G.J. and Shaw, J.M. (1998) Mitochondrial dynamics in yeast. Annu. Rev. Cell Dev. Biol. 14:265-303.

PUBLICATIONS: (undergraduate co authors are underlined)
Pauw, P.G. and Hermann, G.J. (1994) Ouabain is a reversible inhibitor of myogenic fusion. In Vitro Cell. Dev. Biol., 30A, 9-11.

Hermann, G.J., King, E.J. and Shaw, J.M. (1997) The yeast gene, MDM20, is necessary for mitochondrial inheritance and organization of the actin cytoskeleton. J. Cell Biol. 137: 141-153.

Roeder, A.D., Hermann, G.J., Keegan, B.R., Thatcher, S.A., and Shaw, J.M. (1998) Mitochondrial inheritance is delayed in Saccharomyces cerevisiae cells lacking the serine/threonine phosphatase, PTC1. Mol. Biol. Cell 9: 917-930.

Otsuga, D., Keegan, B.R., Brisch, E., Thatcher, J.W., Hermann, G.J., Bleazard, W. and Shaw, J.M. (1998) The dynamin-related GTPase, Dnm1p, controls mitochondrial morphology in yeast. J. Cell Biol. 143:333-349.

Hermann, G.J., Thatcher, J.W., Mills, J.P., Hales, K.G., Fuller, M.T., Nunnari, J. and Shaw, J.M. (1998) Mitochondrial fusion in yeast requires the transmembrane GTPase Fzo1p. J. Cell Biol. 143:359-373.

Hermann, G.J., Leung, B. and Priess, J.P. (1999) Organogenesis of the C. elegans intestine. Dev. Biol. 216:114-134. pdf

Singer, J., Hermann, G.J. and Shaw, J.M. (2000) Suppressors of mdm20 in yeast identify new alleles of ACT1 and TPM1 predicted to enhance actin-tropomyosin interactions. Genetics. 156:523-534.

Hermann, G.J., Leung, B. and Priess, J.P. (2000) Left-right asymmetry in C. elegans intestine organogenesis involves a LIN-12/Notch signaling pathway. Development. 127:3429-3440. pdf

Starr, D.A., Hermann, G.J., Malone, C.J., Fixen, W., Priess, J.R., Horvitz, H.R., and Han, M. (2001) UNC-83 encodes a novel component of the nuclear envelope and is essential for proper nuclear migration. Development. 128:5039-5050.

Hermann, G.J., Schroeder, L.K., Hieb, C.A., Kershner, A.M., Rabbitts, B.M., Fonarev, P., Grant, B.D., and Priess, J.R. (2005) Genetic analysis of lysosomal trafficking in Caenorhabditis elegans. Mol. Biol. Cell 16:3273-3288. pdf

Eisenhut, R.J., Knox, D., and Hermann, G.J. (2005) Characterization of a conserved apoptotic marker expressed in Caenorhabditis elegans phagocytic cells. Biochem. Biophys. Res. Comm. 335:1231-1238. pdf

Schroeder, L.K., Kremer, S., Kramer, M.J., Currie, E., Kwan, E., Watts, J.L., Lawrenson, A.L., and Hermann, G.J. (2007) Function of the Caenorhabditis elegans ABC transporter PGP-2 in the biogenesis of a lysosome-related fat storage organelle. Mol. Biol. Cell 18:995-1008. pdf

Currie, E ., King, B., Lawrenson, A.L., Schroeder, L.K., Kershner, A.M., and Hermann, G.J. (2007) Role of the Caenorhabditis elegans multidrug resistance gene, mrp-4, in gut granule differentiation. Genetics 177:1569-1582. pdf

Rabbitts, B.M., Kokes, M., Miller, N.E., Kramer, M., Lawrenson, A.L., Levitte, S., Kremer, S., Kwan, E., Weis, A.M. and Hermann, G.J. (2008) glo-3, a novel Caenorhabditis elegans gene, is required for lysosome-related organelle biogenesis. Genetics 180:857-871. pdf

Levitte, S., Salesky, R., King, B., Coe Smith, S., Depper, M., Cole, M., Hermann, G.J., (2010) A C. elegans model of orotic aciduria reveals enlarged lysosome-related organelles in embryos lacking umps-1 function. FEBS J. 277:1420-1439. pdf

Hermann, G.J., Scavarda, E., Weis, A.M., Saxton, D.S., Thomas, L.L., Salesky, R., Somhegyi, H., Curtin, T.P., Barrett, A., Foster, O.K., Vine, A., Erlich, K., Kwan, E., Rabbitts, B.M., Warren, K. (2012) C. elegans BLOC-1 functions in trafficking to lysosome-related gut granules. PLoS ONE 7 (8): e43043.

Delahaye, J.L., Foster, O.K., Vine, A., Saxton, D.S., Curtin, T.P., Somhegyi, H., Salesky, R., Hermann, G.J. (2014) C. elegans HOPS and CCZ-1 mediate trafficking to lysosome-related organelles independently of RAB-7 and SAND-1. Mol. Biol. Cell 25:1073-1096. pdf

Barrett, A. and Hermann, G.J. (2016) A Caenorhabditis elegans homologue of LYST functions in endosome and lysosome-related organelle biogenesis. Traffic 17:515-535. pdf

Fridolfsson, H.N., Herrera, L.A., Brandt, J.N., Cain, N.E., Hermann, G.J. and Starr, D.A. (2018) Genetic analysis of nuclear migration and anchorage to study LINC complexes during development of Caenorhabditis elegans. In The LINC Complexes: Methods and Protocols. Methods in Molecular Biology, Springer. 1840:163-180. pdf

Morris, C., Foster, O.K., Handa, S., Peloza, K., Somhegyi, H., Jian, Y., Vo, M.V., Harp, M., Rambo, F.M., Yang, C., and Hermann, G.J. (2018) Function and regulation of the Caenorhabditis elegans Rab32 family member GLO-1 in lysosome-related organelle biogenesis. PLOS Genetics pgen.1007772.

Voss, L., Foster, O.K., Harper, L., Morris, C., Lavoy, S., Brandt, J.N., Peloza, K., Handa, S., Maxfield, A., Harp, M., King, B., Eichten, V., Rambo, F.M., and Hermann, G.J. (2020) An ABCG transporter functions in Rab localization and lysosome-related organelle biogenesis in Caenorhabditis elegans. Genetics 214:419-445. pdf

Brandt, J.N., Voss, L., Rambo, F.M., Nicholson, K., Thein, J.R., Fairchild, L., Seabrook, L., Lewis, D., Guevara-Hernandez, L., White, M.L., Sax, L., Eichten, V., Harper, L., and Hermann, G.J. (2022) Asymmetric organelle positioning during epithelial polarization of C. elegans intestinal cells. Developmental Biology 481:75-94. pdf

undergraduate co-authors