Research in Dr. Storer’s lab will investigate the mechanisms of immunological stimuli on microglial cell activation and examine the ability of gonadal steroids (namely estradiol) to act as suppressors of this activation. Specifically, determination of effects on cytokine production and antigen-presentation abilities from these cells will be the main focus. Various molecular techniques will be utilized in Dr. Storer’s laboratory including nucleic acid spectrophotometry, colorimetric assays in association with nitrite response and viability assessment, end-point and real-time polymerase chain reaction (qPCR), and colorimetric ELISA. Molecular protocols will be using in conjunction with mammalian cell culture techniques. All-in-all, these studies will help contribute to the study of potential therapeutic strategies that target a vital facet of the pathological immune response in the central nervous system.
Dr. Storer is a member of Coe College's Biology Department pstorer@coe.edu